Protein

MIA_04809_1

Length
769 amino acids


Browser: contig06:1044864-1047174+

Protein function

EGGNOG:0PIBCCOG6Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity)
SGD closest match:S000004986COG6Conserved oligomeric Golgi complex subunit 6
CGD closest match:CAL0000198191COG6Conserved oligomeric Golgi complex subunit 6

Protein alignments

%idAln lengthE-value
MCA_05158_159.761%7530.0MCA_05158_1
A0A0J9X8L3_GEOCN48.660%7460.0Similar to Saccharomyces cerevisiae YNL041C COG6 Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking OS=Geotrichum candidum GN=BN980_GECA05s06940g PE=4 SV=1
UniRef50_A0A0J9X8L348.660%7460.0Similar to Saccharomyces cerevisiae YNL041C COG6 Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X8L3_GEOCN
A0A060SZ79_BLAAD38.535%7371.43e-155ARAD1C06182p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06182g PE=4 SV=1
A0A167EXA4_9ASCO35.255%7466.99e-130Cog6p OS=Sugiyamaella lignohabitans GN=COG6 PE=4 SV=1
A0A1E3PL83_9ASCO34.465%7663.00e-118Oligomeric complex COG6 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50122 PE=4 SV=1
Q6C1G5_YARLI29.778%7221.56e-88YALI0F16467p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F16467g PE=4 SV=1
A0A1E4TDN1_9ASCO25.338%5926.57e-45Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4440 PE=4 SV=1
COG6_CANAL25.309%4861.90e-37Conserved oligomeric Golgi complex subunit 6 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=COG6 PE=3 SV=2
COG6_YEAST23.644%4611.10e-22Conserved oligomeric Golgi complex subunit 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COG6 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0096

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. SM01087 (COG6_2)
    2. PF06419 (COG6)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_04809_1
MASLDASFISGTDDLTTATATLSITPESTPLSRPDNAFSQKIASILSTSYTDPSVRQAITSLDSRVRENTGYARRHLRYN
TEAEIIAANGLALKDYSKLIDKLETIGSTITQLTQSFNDMQTKTTTANVTTEPLLTEANKLIEERDSIKVKQVLLDAFKA
KFVISESEIQILTQSSHPINEDFFKALQRVRKTHSDCQALLSTEDDEQMGLDIMQKMTQYLDKAYDRLFFAVQRDLKVAV
SGSKYTGLYKDETTMRKQLSQSLAVLSERPNLFQSALQSLAESRNKVLSTKFVDALTTDTRVEKAIDFYAYDPLRYLGDM
LAYVHAEIVNERETLTSLFEYSYQYHKQHEELQDTDPDLEAIALEGLIDPEETVSQLLDKITSSMIKPLKTRVENVIVSE
TRIPLVYKLIDKLRFYETMYNKAFFAKNNMGVTTTPTTITKNSAPEIMKALEGLVQYGWRQFSKCLEEVIGDIKDRLLVG
SSDLQPPEFLSEAMGNLKEVLQAYEASMVTGTGIVFNSGDKTSEGKESGEESEENGLIDPGNIQKIIQDMTEPFLECCNR
IASDLPDNESELFTINCLDAVKLVLQFYDTICLVKIKQLDGRIEEISDVLVERQHRKFLEESGILPLMPKVHEYYELTTT
RLKQQQQQEKSEEENGKLISRIAELKVAMQDGPLSKEKLAELSFGLDNFLPSATMESLSFLFRLASPRLAQSITMRASQK
FAADFSELERLVLDIYSLEDSKIYFPRTYKDVCVLLAIVDDTMSIRSVR

GO term prediction

Biological Process

GO:0006891 intra-Golgi vesicle-mediated transport

Molecular Function

None predicted.

Cellular Component

GO:0017119 Golgi transport complex