Protein

MIA_04800_1

Length
380 amino acids


Browser: contig06:1030178-1031321-

Protein function

EGGNOG:0PGYSMSW1Tryptophanyl-tRNA synthetase
SGD closest match:S000002676MSW1Tryptophan--tRNA ligase, mitochondrial
CGD closest match:CAL0000182517MSW1Tryptophan--tRNA ligase

Protein alignments

%idAln lengthE-value
MCA_03055_170.332%3910.0MCA_03055_1
A0A0J9X5Z4_GEOCN68.602%3790.0Similar to Saccharomyces cerevisiae YDR268W MSW1 Mitochondrial tryptophanyl-tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA02s07061g PE=3 SV=1
A0A167DEB1_9ASCO59.737%3801.11e-168Tryptophan--tRNA ligase MSW1 OS=Sugiyamaella lignohabitans GN=MSW1 PE=3 SV=1
A0A060T057_BLAAD57.632%3802.09e-162ARAD1C13970p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C13970g PE=3 SV=1
Q6CBI6_YARLI54.424%3731.07e-138YALI0C18425p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C18425g PE=3 SV=1
A0A1E3PI03_9ASCO52.895%3808.94e-138Tryptophanyl-tRNA synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_42344 PE=3 SV=1
Q5AG80_CANAL50.667%3755.39e-130Tryptophan--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MSW1 PE=3 SV=1
UniRef50_A3LVM549.307%3611.05e-124Mitochondrial tryptophanyl-tRNA synthetase n=43 Tax=Saccharomycetales TaxID=4892 RepID=A3LVM5_PICST
SYWM_YEAST45.550%3821.81e-118Tryptophan--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSW1 PE=1 SV=2
A0A1E4TK09_9ASCO42.938%3542.02e-97Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_643 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5633

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 380

Detailed signature matches

    1. PF00579 (tRNA-synt_1b)
    1. cd00806 (TrpRS_core)
    2. PR01039 (TRNASYNTHTRP)
    1. PS00178 (AA_TRNA_LI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF52374 (Nucleotid...)

Residue annotation

  1. active site cd00806
  2. HIGH motif cd00806
  3. dimer interface cd...
  4. KMSKS motif cd00806

Protein sequence

>MIA_04800_1
MSAAAVRSAKSTVLDLAATVLPAKSTVFSMIQPTGVFHVGNYLGAVKSWVDIQNQTAAAFPNSNDPSAPRLLFGIADLHA
LTIPKDPKVLRFTRSQAVASMLATGIDPSRCIVFQQSQVPEHTQLYWLLSTITGMGYLNRMTQWKSKAQLDESISLTDAS
ESALSKLHLGLFAYPCLQAADILLYKSSYVPVGEDQSQHLELTRHICAAFNKKYPGANKAPIFPEPKTIFAPFKKISSLR
DPSKKMSKSDPDQTACIYIPDPPARIQKAIRRAVTDSQQGPITYDPVARPGIANLLEMASGILQTTPQQVLDDMAPKDHK
ELKDGVAQVIAEGLAPVRTEYERLMKDLDYVDDVARRGSLRAREIAAVTMAEVNRAVGLN

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006436 tryptophanyl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004830 tryptophan-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm