Protein

MIA_04785_1

Length
774 amino acids

Browser: contig06:975756-978081-

Protein function

EGGNOG:0PIR2DBP6ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs (By similarity)
SGD closest match:S000005321DBP6ATP-dependent RNA helicase DBP6
CGD closest match:CAL0000190599DBP6ATP-dependent RNA helicase DBP6

Protein alignments

%idAln lengthE-value
MCA_05066_155.571%7180.0MCA_05066_1
A0A0J9X9Z5_GEOCN45.455%6714.20e-153Similar to Saccharomyces cerevisiae YNR038W DBP6 Essential protein involved in ribosome biogenesis OS=Geotrichum candidum GN=BN980_GECA06s03596g PE=3 SV=1
UniRef50_A0A0J9X9Z545.455%6718.60e-150Similar to Saccharomyces cerevisiae YNR038W DBP6 Essential protein involved in ribosome biogenesis n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X9Z5_GEOCN
A0A161HIR3_9ASCO46.107%4886.67e-107Dbp6p OS=Sugiyamaella lignohabitans GN=DBP6 PE=3 SV=1
A0A1E3PPN0_9ASCO37.964%6193.65e-97p-loop containing nucleoside triphosphate hydrolase protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_14658 PE=3 SV=1
A0A060T2Q6_BLAAD40.377%5305.10e-86ARAD1C30096p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C30096g PE=3 SV=1
DBP6_CANAL37.983%4664.92e-66ATP-dependent RNA helicase DBP6 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DBP6 PE=3 SV=2
DBP6_YARLI37.872%4702.05e-65ATP-dependent RNA helicase DBP6 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DBP6 PE=3 SV=1
A0A1E4TL13_9ASCO37.365%4631.57e-65Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12107 PE=3 SV=1
DBP6_YEAST34.450%4181.00e-49ATP-dependent RNA helicase DBP6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DBP6 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0045

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 774

Detailed signature matches

  1. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  2. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  5. SITE IPR000629
    ATP-dependent RNA helicase DEAD-box, conserved site
    1. PS00039 (DEAD_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd00079 (HELICc)
  3. mobidb-lite (disord...)

Residue annotation

  1. nucleotide binding...
  2. ATP-binding site c...

Protein sequence

>MIA_04785_1
MPVTDHKKRKRSADTEDDAPKSVTMEDIQLPDYSNDEDSSDDDLSNDSSDDVSDDDSSDDSGDSDDESESDSKDKPLSKT
SPTETPAAQPTETADQEPSQPQEKPKIDTRFAEFYKRFQSAARNIALSAYNVDQEKDEFGNVKAVKALPMDAVEDAEADK
EVRAVMQRREAAAVPQGLVPLPVPEIDPFENDEEADADGVMDESGTPDLAQLRKKLARPGADGGVGGALPPWLAHPIHVS
STVVIPFDHIEGLSDNLKKSIKSGLGYQDAFAVQATLLPPLLAATADISPDPRPDILVNAATGSGKTLAYTIPIVQALST
RVVPQLRAVVLLPTRPLITQVVHVFRTLAASASTKLHITSLHGDHTLRSEQERLLKTTPDIIVSTPGRLVDHLRLGTISL
SHLQYLVVDEADRLLSDSFNEWATVVTRTIDEASETTLDDTPNTSLLKNLRVRKWSRPAQKLIFSATLTRDPGKLAMLRI
RDPQVYIIGGETGSDESSATKSSITGTPASTDGKEFTVPRTLTERLVPIKSISVKPLRLMQLISLHQGHSKGIQDSSMKS
HVLVFVNSNELAARLARLLTLLDEEVFHLGLVYQRCSSEQPAAVRRRVLRAFAATSTATQSSSEEGPINVLVCTDLVARG
IDISSVRNVINYDIPRGPRDYVHRVGRTARAGQAGTAWSFAADRRDHGRFWRGISDHIFREGKEPAPGSSADTDGDVGMG
AEGEEDKPEKEASSAVEKYELEELVPQEGTRDYERVEEGYGRALQRLGKEVHGN

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0005524 ATP binding

Cellular Component

None predicted.