Protein

MIA_04765_1

Length
578 amino acids

Browser: contig06:933700-935601+

Protein function

EGGNOG:0PFFSADA2SAGA complex subunit Ada2
SGD closest match:S000002856ADA2Transcriptional adapter 2
CGD closest match:CAL0000192402ADA2Transcriptional adapter 2

Protein alignments

%idAln lengthE-value
MCA_04088_172.595%5510.0MCA_04088_1
A0A0J9XJ81_GEOCN75.641%3123.74e-174Transcriptional adapter 2 OS=Geotrichum candidum GN=BN980_GECA18s01770g PE=4 SV=1
Q6C1P9_YARLI68.269%3123.96e-158Transcriptional adapter 2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F14443g PE=4 SV=1
UniRef50_Q6C1P968.269%3129.17e-155Transcriptional adapter 2 n=4 Tax=Saccharomycetales TaxID=4892 RepID=Q6C1P9_YARLI
A0A060T7U3_BLAAD66.562%3201.89e-154Transcriptional adapter 2 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B22770g PE=4 SV=1
A0A1E4TJV2_9ASCO66.026%3122.28e-147Transcriptional adapter 2 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_80929 PE=4 SV=1
ADA2_CANAL61.613%3102.17e-139Transcriptional adapter 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADA2 PE=3 SV=2
A0A1E3PDK8_9ASCO67.254%2843.03e-135Transcriptional adapter 2 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_43807 PE=4 SV=1
ADA2_YEAST59.486%3112.95e-130Transcriptional adapter 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADA2 PE=1 SV=1
A0A167E8F6_9ASCO68.302%2652.65e-120Transcriptional adapter 2 OS=Sugiyamaella lignohabitans GN=ADA2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0052

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 578

Detailed signature matches

  1. Family IPR016827
    Transcriptional adaptor 2
    1. PIRSF025024 (Txn_ad...)
  2. Domain IPR000433
    Zinc finger, ZZ-type
    1. PF00569 (ZZ)
    2. PS01357 (ZF_ZZ_1)
    3. PS50135 (ZF_ZZ_2)
    4. SM00291 (zz_5)
  3. Domain IPR009057
    Homeobox domain-like
    1. SSF46689 (Homeodoma...)
  4. Domain IPR001005
    SANT/Myb domain
    1. PF00249 (Myb_DNA-bi...)
    2. SM00717 (sant)
  5. Domain IPR007526
    SWIRM domain
    1. PF04433 (SWIRM)
    2. PS50934 (SWIRM)
  6. Domain IPR017884
    SANT domain
    1. PS51293 (SANT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.10.60
  2. SSF57850 (RING/U-box)
  3. cd00167 (SANT)
  4. cd02335 (ZZ_ADA2)
  5. mobidb-lite (disord...)

Residue annotation

  1. zinc cluster 1 cd0...
  2. Zinc-binding sites...
  3. putative charged b...
  4. putative hydrophob...
  5. zinc cluster 2 cd0...
  6. DNA binding site c...

Protein sequence

>MIA_04765_1
MYIYTPLSLTTDPHLYEKQPHAHANSQLVERLLSNVCVWFHCDACSCDCTNLVRIRCAECPDYDLCVLCFSQGKSSGNHK
PWHDYRIVEQHAYPIFDEDWGADEELFLIEGMKSHGVGNWQDIADHIGGRSKEEVEQHYKKIYLESDTYPVPNLKRKFNI
DPSEFAERRRQRIEDRRAKSRKLLPPKQKPTASVPSCHEVQGYMPGRLEFETEYENEAEMSVKDMVFDPEDNETEVELKL
TVLDIYNSRLTSRAERKRVMLEHGLLEYRKNVALDKKRSKEEKDILNSRIRVFARLLTPEDYQQFATSVLTELQCRRRIA
ELQEYRRNGLRTFSDAQKYETDKAVRLATLSLTASHGGNGGNGGSGGGLGGSGGGGGGGSRYTANSMAAASSSRYAAGLG
GSGRAHHGATSGHIDLHATNHHHFIYGSNGRSGATTPHLSSRHSSVPVSAAAAAAANGRGGSVTPVPGSVGPDPDEIAAA
TAARLASLSARLFRKPAANPLDISKAADVELLSPEEQMLCSQLRILPKPYLAIKETLFRELLKSGGVLKKRTARELIKID
VNKTARIYEFFRSQRWIS

GO term prediction

Biological Process

GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0035065 regulation of histone acetylation

Molecular Function

GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008270 zinc ion binding

Cellular Component

None predicted.