Protein

MCA_04088_1

Length
550 amino acids

Gene name: ADA2

Description: Transcriptional adapter 2; protein with ZZ type Zinc finger, SANT/Myb and SWIRM domains

Browser: contigC:1981098-1982807+

RNA-seq: read pairs 1492, FPKM 33.5, percentile rank 55.7% (100% = highest expression)

Protein function

Annotation:ADA2Transcriptional adapter 2; protein with ZZ type Zinc finger, SANT/Myb and SWIRM domains
KEGG:K11314TADA2A transcriptional adapter 2-alpha
EGGNOG:0PFFSADA2SAGA complex subunit Ada2
SGD closest match:S000002856ADA2Transcriptional adapter 2
CGD closest match:CAL0000192402ADA2Transcriptional adapter 2

Protein alignments

%idAln lengthE-value
MIA_04765_173.38%5410.0MIA_04765_1
A0A0J9XJ81_GEOCN76.25%3202e-175Transcriptional adapter 2 OS=Geotrichum candidum GN=BN980_GECA18s01770g PE=4 SV=1
A0A1E4TJV2_9ASCO64.39%3372e-155Transcriptional adapter 2 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_80929 PE=4 SV=1
Q6C1P9_YARLI68.27%3121e-154Transcriptional adapter 2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F14443g PE=4 SV=1
UniRef50_Q6C1P968.27%3123e-151Transcriptional adapter 2 n=4 Tax=Saccharomycetales TaxID=4892 RepID=Q6C1P9_YARLI
A0A060T7U3_BLAAD65.38%3122e-148Transcriptional adapter 2 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B22770g PE=4 SV=1
ADA2_CANAL60.65%3101e-134Transcriptional adapter 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADA2 PE=3 SV=2
A0A1E3PDK8_9ASCO59.64%3371e-133Transcriptional adapter 2 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_43807 PE=4 SV=1
ADA2_YEAST58.01%3122e-124Transcriptional adapter 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADA2 PE=1 SV=1
A0A167E8F6_9ASCO68.05%2664e-115Transcriptional adapter 2 OS=Sugiyamaella lignohabitans GN=ADA2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0236

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 550

Detailed signature matches

  1. Family IPR016827
    Transcriptional adaptor 2
    1. PIRSF025024 (Txn_ad...)
  2. Domain IPR000433
    Zinc finger, ZZ-type
    1. PF00569 (ZZ)
    2. PS01357 (ZF_ZZ_1)
    3. PS50135 (ZF_ZZ_2)
    4. SM00291 (zz_5)
  3. Domain IPR009057
    Homeobox domain-like
    1. SSF46689 (Homeodoma...)
  4. Domain IPR001005
    SANT/Myb domain
    1. PF00249 (Myb_DNA-bi...)
    2. SM00717 (sant)
  5. Domain IPR007526
    SWIRM domain
    1. PS50934 (SWIRM)
    2. PF04433 (SWIRM)
  6. Domain IPR017884
    SANT domain
    1. PS51293 (SANT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.10.60
  2. SSF57850 (RING/U-box)
  3. cd00167 (SANT)
  4. cd02335 (ZZ_ADA2)
  5. mobidb-lite (disord...)

Residue annotation

  1. zinc cluster 1 cd0...
  2. Zinc-binding sites...
  3. putative charged b...
  4. putative hydrophob...
  5. zinc cluster 2 cd0...
  6. DNA binding site c...

Protein sequence

>MCA_04088_1
MTVVNRTNAPANPLKAGEPGQKFHCDVCACDCSNLVRIRCAECTDYDLCVICFSKGKSSGNHKPWHKYMIVEQHAYPIFD
EDWGADEELLLIEGMKTFGVGNWQDIADHIGGRSKEEVEEHYKRVYLESETYPVPNLKRKFNIDPSEFIEKRRRRIEDRR
ANAMKLLPPKQKPTASVPSCHEVQGYMPGRLEFESEYENEAEMLVKDMIFEPEDNETEIELKLTVLDIYNSRLTSRAERK
RVMIQHGLLDYRKNVALDKKRSKEEKDLLNTRLRVFARLMTPQDFNNFQTSVLAELYFRKRIAELQEYRRNGIRSFADAQ
KYETDKAVRMATLNISGGGSGSSGLSSSPLSSHHVGSSRHTATSWAAASSRYAGNLAVQAKAAAAAAAAGHADLHSTNHH
HFTYTGSGTVTPQLQITVGGTSGASTPSRSLSVPPTDETDSANNTPESIAQATAARLATLNAKLFRKPVANPLDISHAPD
VELLSPEEQMLCSQLRILPKPYLAIKETLFRELLRNGGTLKKRTARELLKIDVNKTARIYEFFQSQRWIS

GO term prediction

Biological Process

GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0035065 regulation of histone acetylation

Molecular Function

GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008270 zinc ion binding

Cellular Component

None predicted.