Protein

MIA_04751_1

Length
810 amino acids

Browser: contig06:895838-898271-

Protein function

EGGNOG:0PG0YMDL1ATP-dependent permease
SGD closest match:S000006191MDL2ATP-dependent permease MDL2, mitochondrial
CGD closest match:CAL0000191535MDL1ATP-binding cassette permease

Protein alignments

%idAln lengthE-value
MCA_05098_182.820%6170.0MCA_05098_1
A0A0J9X7R2_GEOCN77.832%6180.0Similar to Saccharomyces cerevisiae YLR188W MDL1 Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter OS=Geotrichum candidum GN=BN980_GECA04s05543g PE=4 SV=1
A0A060T128_BLAAD66.875%6400.0ARAD1C13288p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C13288g PE=4 SV=1
A0A167FDS2_9ASCO62.722%6760.0ATP-binding cassette permease MDL2 OS=Sugiyamaella lignohabitans GN=MDL2 PE=4 SV=1
UniRef50_A0A167FDS262.722%6760.0ATP-binding cassette permease MDL2 n=14 Tax=Ascomycota TaxID=4890 RepID=A0A167FDS2_9ASCO
Q6C7H1_YARLI57.977%7020.0YALI0E00880p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E00880g PE=4 SV=1
A0A1E3PT16_9ASCO61.626%6150.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_20529 PE=4 SV=1
A0A1E4TC77_9ASCO53.356%5960.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_138899 PE=4 SV=1
MDL2_YEAST51.575%6030.0ATP-dependent permease MDL2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDL2 PE=1 SV=3
Q5A951_CANAL49.169%6022.30e-173ATP-binding cassette permease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MDL1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9978
Predicted cleavage: 112

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 810

Detailed signature matches

  1. Domain IPR011527
    ABC transporter type 1, transmembrane domain
    1. PS50929 (ABC_TM1F)
    2. PF00664 (ABC_membrane)
    3. SSF90123 (ABC trans...)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR003439
    ABC transporter-like
    1. PF00005 (ABC_tran)
    2. PS50893 (ABC_TRANSP...)
  4. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
  5. SITE IPR017871
    ABC transporter, conserved site
    1. PS00211 (ABC_TRANSP...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. G3DSA:1.20.15...
  4. G3DSA:3.40.50...
  5. NON_CYTOPLASM... (N...)
  6. TMhelix
  7. TRANSMEMBRANE (Tran...)
  8. cd03249 (ABC_MTABC3...)
  9. mobidb-lite (disord...)

Residue annotation

  1. Walker A/P-loop cd...
  2. ATP binding site c...
  3. Q-loop/lid cd03249
  4. ABC transporter si...
  5. Walker B cd03249
  6. D-loop cd03249
  7. H-loop/switch regi...

Protein sequence

>MIA_04751_1
MRPSASCSAAALPLLPRILQHGQSKLLSLRMRPPAAPSPASTHPSASSAISSLLPRPARARLYSCAVKQSPINPPQHTII
PRSHLIPPFPSLQYLPNASFRRCLSTSPDSDPPPVPSKQPPSDSFEKSERAKQASQVNLSARLSPRDTSNKAAGLKEIGR
LFSLARREVKPLFFAVLLLVLSSAVTLTLPMTIGKILDAANADTAEKLVFGLPLPTFYAGVAALFVVGAAANFGRVVLLR
VIGERLVARLRVTLFKKTVSQDAEFFDANRVGDLISRLSSDANIVAKSLTQNVSDGLRSSLSAVFGIGMMAYVSLKLTSL
IVLVIPPIFLGSVIYGRKVRQLSRELQASIGELTKVSEERLSNVRTAQSFAGEIQEIHRYSDKIRDVFRIGRSEAIAAAS
FFASTGFAGNLTVLGLLAIGSQMVSSGEMTLGALTSFTMYTGYAGSSAFGLSSFYSELMKGAGAASRLFELMDREPSIKP
TVGKKLVQARETISFDHVKFSYPTRPAVPIFNDLTFQIPSGSNVCVVGPSGSGKSTITSLLLRFYDPTGGAIRIGNDDIR
DLNLKSLRRQIGVVSQEPVLFSGTIAENISYGRPDASRAEIFMAAKRANCGFISDFPEGLDTAVGARGAQLSGGQKQRIA
IARALIKNPSILILDEATSALDSESEAAVNEALVNLMDQKNTTTISIAHRLSTIKRSDQIIVVGSNGTVAEVGSFHELIV
DPNSALSQLLKAQAKDVLEEYEPVALEKHEEDDKISGVVGGVPEEIALANNGESETFVEEQVDEDLARQESEQEDKDVSA
GINIKKISNF

GO term prediction

Biological Process

GO:0006810 transport
GO:0055085 transmembrane transport

Molecular Function

GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances

Cellular Component

GO:0016021 integral component of membrane