MCA_05098_1
Gene name: MDL1
Description: ATP-binding cassette (ABC) transporter, mitochondrial
Browser: contigD:352698-355110-
RNA-seq: read pairs 3670, FPKM 56.4, percentile rank 68.0% (100% = highest expression)
Protein function
| Annotation: | MDL1 | ATP-binding cassette (ABC) transporter, mitochondrial | |
|---|---|---|---|
| KEGG: | K02021 | ABC.MR | putative ABC transport system ATP-binding protein |
| EGGNOG: | 0PG0Y | MDL1 | ATP-dependent permease |
| SGD closest match: | S000004178 | MDL1 | ATP-dependent permease MDL1, mitochondrial |
| CGD closest match: | CAL0000191535 | MDL1 | ATP-binding cassette permease |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04751_1 | 82.69% | 618 | 0.0 | MIA_04751_1 |
| A0A0J9X7R2_GEOCN | 77.15% | 617 | 0.0 | Similar to Saccharomyces cerevisiae YLR188W MDL1 Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter OS=Geotrichum candidum GN=BN980_GECA04s05543g PE=4 SV=1 |
| A0A060T128_BLAAD | 69.32% | 616 | 0.0 | ARAD1C13288p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C13288g PE=4 SV=1 |
| A0A167FDS2_9ASCO | 64.62% | 619 | 0.0 | ATP-binding cassette permease MDL2 OS=Sugiyamaella lignohabitans GN=MDL2 PE=4 SV=1 |
| UniRef50_A0A167FDS2 | 64.62% | 619 | 0.0 | ATP-binding cassette permease MDL2 n=14 Tax=Ascomycota TaxID=4890 RepID=A0A167FDS2_9ASCO |
| Q6C7H1_YARLI | 62.44% | 615 | 0.0 | YALI0E00880p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E00880g PE=4 SV=1 |
| A0A1E3PT16_9ASCO | 60.78% | 617 | 0.0 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_20529 PE=4 SV=1 |
| MDL1_YEAST | 55.80% | 595 | 0.0 | ATP-dependent permease MDL1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDL1 PE=1 SV=2 |
| A0A1E4TC77_9ASCO | 52.60% | 597 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_138899 PE=4 SV=1 |
| Q5A951_CANAL | 47.76% | 603 | 0.0 | ATP-binding cassette permease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MDL1 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9955
Predicted cleavage: 82
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
Detailed signature matches
no IPR
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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PIRSF002773 (ABC_pr...)
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TRANSMEMBRANE (Tran...)
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cd03249 (ABC_MTABC3...)
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mobidb-lite (disord...)
Residue annotation
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Walker A/P-loop cd...
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ATP binding site c...
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Q-loop/lid cd03249
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ABC transporter si...
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Walker B cd03249
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D-loop cd03249
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H-loop/switch regi...
Protein sequence
>MCA_05098_1 MSTPTLIQRQALRLAGVASKVNSIGSINPYHIPITTVSPLIRNCSKRTFISISIVKSHTQPTKHFKFQNLSSSFSTYTGR LNSQKTHNLSSKTSENTKPIEQEQKPEEQENSNEPPHQFEKSEKAMAASKVNLSARLSRRDAPPAGGFKEIMRLFSLAKR EAKPLFLAISLLFISSAVTLTLPMTIGKILDVSTSSGPAEEKLVFGLQLPYFYTAVASLFVIGALANFGRVVMLRIIGER LVARLRVHLFKKTISQDAEFFDANRVGDLISRLSSDANIVAKSLTQNVSDGLRSSLSAFFGIAMMAYVSLKLTSMIVLVV PPIFLGSYIYGKKVRQLSRELQAAVGDLTKVSEERLSNVKTSQAFAGEIQEIHRYSEKIRSVFRIGKSEAIAAASFFAST GLAGNLTVLSLLAIGSGMVSSGEMTLGALTSFTMYTGYAGSSAFGLSSFYSELMKGAGAASRLFELMDREPSIKPTVGRK LISAKDLPISFEHVKFAYPTRPAVDIFQDLTFTITPGSNVCVVGPSGGGKSTITSLLLRFYDPTSGAVKIGDTDIRELNL KSLRRQIGVVSQEPVLFGGTIAENIAYAKPDATRQEIYDAARRANCGFISDFPDGLDTYVGARGAQLSGGQKQRIAIARA LIKQPAILILDEATSALDSESESAVNEALVRLMDERNTTTISIAHRLSTIKRSDQLIVLGSDGRVAEVGHFNELISNPNS ALSKLLQAQAKDLLDSSASMSAGSADAVSPTEEINIMEVGRDCVDEEPEEILEREVEEELQQQEEEQEKRDVSGIDLNIP RRP
GO term prediction
Biological Process
GO:0006810 transport
GO:0055085 transmembrane transport
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Cellular Component
GO:0016021 integral component of membrane