Protein

MIA_04713_1

Length
537 amino acids

Browser: contig06:797199-798813-

Protein function

EGGNOG:0PFG2SUB8serine protease
SGD closest match:S000000786PRB1Cerevisin
CGD closest match:CAL0000175297orf19.7196Proteinase B

Protein alignments

%idAln lengthE-value
Q6CED6_YARLI41.176%4931.13e-99YALI0B16500p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B16500g PE=3 SV=1
A0A0J9XFX0_GEOCN37.361%5387.22e-98Similar to Saccharomyces cerevisiae YOR003W YSP3 Putative to the subtilisin-like protease III OS=Geotrichum candidum GN=BN980_GECA14s01814g PE=3 SV=1
UniRef50_W1QEH538.104%5385.67e-92Cerevisin n=16 Tax=saccharomyceta TaxID=716545 RepID=W1QEH5_OGAPD
A0A170QYI2_9ASCO37.885%5204.66e-95Proteinase B OS=Sugiyamaella lignohabitans GN=PRB1 PE=3 SV=1
MCA_03016_138.306%5438.69e-94MCA_03016_1
A0A060T675_BLAAD37.882%4912.03e-92ARAD1B09218p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B09218g PE=3 SV=1
A0A1D8PRH0_CANAL38.289%4914.14e-90Proteinase B OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7196 PE=3 SV=1
PRTB_YEAST41.935%4032.20e-87Cerevisin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRB1 PE=1 SV=1
A0A1E3PKP3_9ASCO43.325%3975.62e-87Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82571 PE=3 SV=1
A0A1E4THC1_9ASCO38.734%3953.91e-63Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_65053 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0691
Predicted cleavage: 35

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 500 537

Detailed signature matches

  1. Family IPR015500
    Peptidase S8, subtilisin-related
    1. PR00723 (SUBTILISIN)
  2. Domain IPR010259
    Peptidase S8 propeptide/proteinase inhibitor I9
    1. G3DSA:3.30.70.80
  3. Domain IPR000209
    Peptidase S8/S53 domain
    1. PF00082 (Peptidase_S8)
    2. G3DSA:3.40.50...
    3. SSF52743 (Subtilisi...)
  4. Domain IPR034193
    Proteinase K-like catalytic domain
    1. cd04077 (Peptidases...)
  5. SITE IPR023827
    Peptidase S8, subtilisin, Asp-active site
    1. PS00136 (SUBTILASE_ASP)
  6. SITE IPR022398
    Peptidase S8, subtilisin, His-active site
    1. PS00137 (SUBTILASE_HIS)
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SignalP-noTM

Residue annotation

  1. calcium binding si...
  2. active site cd04077
  3. catalytic triad cd...
  4. calcium binding si...

Protein sequence

>MIA_04713_1
MKLPSLIYLVWLATATTAAYIPHHQLQLEQPRRIHPVPLLAAAKPPSDSSNEDPVIEHSYIVVFDTSALKSVPPDEINNM
VQDHLAWVTRARELHLASLALDSPQSNQKEYPHQQLLSSPSSSHIFTTPLQPFSIHNNTLLGYTGYLPPETLALIRSSAF
FSFPAGMLGGPQQLPIAYIEPNARVFASKLVTQTYAPWGLARISNREQLTASTFSKYRYDDRGGAGVTAYVVDSGIYVEH
DDFEGRAEWGVVTVEEGDQNAGGNKGASDGDGEPGYRGLVYQDLNGHGTHCAGIIAGKAYGVAKKTRLVAVKVLAADGSG
SIESVLRGLEWVVNNHRNQSAALSSLSDDDKNRNSSRGAIVNLSLGCGYSASLNAAVAAVAAAGLHAVVSAGNDNGDACE
YSPASSQAALTVGASTFEDTRAWFSNEGACVDLFAPGTDVWSDFIDAPDAAARRSGTSMAAPYVGGLMAYFLALQPLEED
DGHGGVRAVAPVTPAQMRENVRRFATHNALYGVANGTSNLLAYNGGGMRDLDDFWRV

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004252 serine-type endopeptidase activity

Cellular Component

None predicted.