Protein

MIA_04702_1

Length
543 amino acids

Browser: contig06:761941-763573-

Protein function

EGGNOG:0PFG2SUB8serine protease
SGD closest match:S000000786PRB1Cerevisin
CGD closest match:CAL0000175297orf19.7196Proteinase B

Protein alignments

%idAln lengthE-value
A0A0J9XFX0_GEOCN72.996%4740.0Similar to Saccharomyces cerevisiae YOR003W YSP3 Putative to the subtilisin-like protease III OS=Geotrichum candidum GN=BN980_GECA14s01814g PE=3 SV=1
MCA_03016_173.207%4740.0MCA_03016_1
Q6CED6_YARLI67.209%4300.0YALI0B16500p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B16500g PE=3 SV=1
A0A170QYI2_9ASCO65.429%4310.0Proteinase B OS=Sugiyamaella lignohabitans GN=PRB1 PE=3 SV=1
A0A1E3PKP3_9ASCO65.376%4390.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82571 PE=3 SV=1
A0A060T675_BLAAD62.212%4347.81e-170ARAD1B09218p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B09218g PE=3 SV=1
A0A1D8PRH0_CANAL63.256%4307.30e-168Proteinase B OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7196 PE=3 SV=1
UniRef50_W1QEH562.005%4293.35e-163Cerevisin n=16 Tax=saccharomyceta TaxID=716545 RepID=W1QEH5_OGAPD
PRTB_YEAST59.633%4361.10e-153Cerevisin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRB1 PE=1 SV=1
A0A1E4THC1_9ASCO53.333%4501.04e-124Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_65053 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0748

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 400 450 500 543

Detailed signature matches

  1. Family IPR015500
    Peptidase S8, subtilisin-related
    1. PR00723 (SUBTILISIN)
  2. Domain IPR010259
    Peptidase S8 propeptide/proteinase inhibitor I9
    1. PF05922 (Inhibitor_I9)
    2. G3DSA:3.30.70.80
  3. Domain IPR009020
    Protease propeptides/proteinase inhibitor I9
    1. SSF54897 (Protease ...)
  4. Domain IPR000209
    Peptidase S8/S53 domain
    1. PF00082 (Peptidase_S8)
    2. G3DSA:3.40.50...
    3. SSF52743 (Subtilisi...)
  5. Domain IPR034193
    Proteinase K-like catalytic domain
    1. cd04077 (Peptidases...)
  6. SITE IPR022398
    Peptidase S8, subtilisin, His-active site
    1. PS00137 (SUBTILASE_HIS)
  7. SITE IPR023828
    Peptidase S8, subtilisin, Ser-active site
    1. PS00138 (SUBTILASE_SER)
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SignalP-noTM

Residue annotation

  1. calcium binding si...
  2. active site cd04077
  3. catalytic triad cd...
  4. calcium binding si...

Protein sequence

>MIA_04702_1
MKVAVVAASLLPLAANVANAIYIPTDPEMLAQLSRLEHGKKAPVPAVPAVPVAQPPSSPDHIIMPLAPFATSEHAKKNLV
EDSYIIIFNDNVDDALISQHLVWLSDAHAEAVSALHKRDSQHPFLVAGEGEEALATGGLKHVYSLPTGLKGYSGRFLPET
IEAIRTHSSLVKFVEHDSRVFASEFATEKDAPWGLARISHKRPLSLSTFNKYLYDDDGGEGVTSYVIDTGTNIDHVDFGG
RASWGKTIPSGDSDSDGNGHGTHCSGTIAGEKYGVAKKANIVAVKVLRSNGSGTMSDVLKGVEWAASAHIAAVKADKKGF
KGSTANMSLGGGKSPSLDLAVNAAVKAGIHFAVAAGNDNADACNYSPAAAADAVTVGASDISDVRAYFSNYGKCVDIFGP
GVNIQSTYIGSKYAVATLSGTSMASPHVAGILSYFLSLQPASDSEYAVAGAVTPAQLKKNLISYSTSGILEDIPADTPNK
LIFNGAGGNITDFWSHGAAAAAADAASDAEQSFRISEELKRVSDDIGGFLDGLRDRLLKGVNY

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004252 serine-type endopeptidase activity

Cellular Component

None predicted.