Protein

MIA_04678_1

Length
370 amino acids

Browser: contig06:713235-714430-

Protein function

EGGNOG:0PMDGDNA mismatch repair protein
SGD closest match:S000004025MLH2DNA mismatch repair protein MLH2
CGD closest match:CAL0000197853PMS1ATP-binding mismatch repair protein

Protein alignments

%idAln lengthE-value
MCA_01319_137.644%3481.25e-58MCA_01319_1
A0A0J9XAS6_GEOCN34.986%3632.40e-49Similar to Saccharomyces cerevisiae YLR035C MLH2 Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic recombination OS=Geotrichum candidum GN=BN980_GECA07s03662g PE=4 SV=1
UniRef50_A0A0J9XAS634.986%3634.91e-46Similar to Saccharomyces cerevisiae YLR035C MLH2 Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic recombination n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XAS6_GEOCN
A0A060T8K1_BLAAD29.720%2865.30e-22ARAD1D12122p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D12122g PE=4 SV=1
A0A167FC59_9ASCO35.135%2226.47e-22Pms1p OS=Sugiyamaella lignohabitans GN=PMS1 PE=4 SV=1
A0A1D8PII6_CANAL29.646%2265.85e-19ATP-binding mismatch repair protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMS1 PE=4 SV=1
A0A1E3PGR0_9ASCO31.193%2181.48e-16DNA mismatch repair protein MutL OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53089 PE=4 SV=1
MLH2_YEAST33.014%2094.88e-16DNA mismatch repair protein MLH2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MLH2 PE=1 SV=1
A0A1E4TDN3_9ASCO29.577%2848.54e-12Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147756 PE=4 SV=1
Q6CCE6_YARLI29.487%1565.68e-11YALI0C10032p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C10032g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0559

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 370

Detailed signature matches

  1. Domain IPR003594
    Histidine kinase-like ATPase, C-terminal domain
    1. G3DSA:3.30.56...
    2. SSF55874 (ATPase do...)
  2. Domain IPR020568
    Ribosomal protein S5 domain 2-type fold
    1. SSF54211 (Ribosomal...)
  3. Domain IPR014721
    Ribosomal protein S5 domain 2-type fold, subgroup
    1. G3DSA:3.30.23...
  4. Domain IPR013507
    DNA mismatch repair protein, C-terminal
    1. SM01340 (DNA_mis_re...)
    2. PF01119 (DNA_mis_re...)
  5. SITE IPR014762
    DNA mismatch repair, conserved site
    1. PS00058 (DNA_MISMAT...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PF13589 (HATPase_c_3)
  2. cd00075 (HATPase_c)
  3. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. Mg2+ binding site ...
  3. G-X-G motif cd00075

Protein sequence

>MIA_04678_1
MLRASVIITSAVAVIKELVENALDAGATSVQITMDHTTLGSISVADNGSGIAKRDRGLAAAANATSKIRTYDDIETTNTL
GFRGEALAAIADIAGGSAGGMTMTTRVAKEQVAVQWRVDRGGRFQAGSLTFVAAPVGTTVKVEGLFARYPVRRRILLAER
AQTIRNASQLVLEYALVYPHVRVEFCVRASGGSGRNQSHEIIKVYSGGKTALERLASAFGARAVQHLISGEVIDGAGEDA
WKWRYVIPAGEGVKHGREEGEQSKTKPMVNVFAINGRPMRGKHGHAARLMKKINQTLREGRVWVVWVDVPVGWVDVNVEP
GKDDIVFRDLEEAEARVGSFLGRAYAQEGEASRQYQESDTITNASGTGGS

GO term prediction

Biological Process

GO:0006298 mismatch repair

Molecular Function

GO:0005524 ATP binding
GO:0030983 mismatched DNA binding

Cellular Component

None predicted.