Protein

MCA_01319_1

Length
784 amino acids

Gene name: PMS1

Description: ATP-binding mismatch repair protein

Browser: contigA:4145861-4148286-

RNA-seq: read pairs 253, FPKM 4.0, percentile rank 15.8% (100% = highest expression)

Protein function

Annotation:PMS1ATP-binding mismatch repair protein
KEGG:K10864PMS1 DNA mismatch repair protein PMS1
EGGNOG:0PMDGDNA mismatch repair protein
SGD closest match:S000004025MLH2DNA mismatch repair protein MLH2
CGD closest match:CAL0000197853PMS1ATP-binding mismatch repair protein

Protein alignments

%idAln lengthE-value
MIA_04678_139.94%3482e-76MIA_04678_1
A0A0J9XAS6_GEOCN37.47%4272e-67Similar to Saccharomyces cerevisiae YLR035C MLH2 Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic recombination OS=Geotrichum candidum GN=BN980_GECA07s03662g PE=4 SV=1
UniRef50_A0A0J9XAS637.47%4275e-64Similar to Saccharomyces cerevisiae YLR035C MLH2 Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic recombination n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XAS6_GEOCN
A0A060TCK7_BLAAD26.43%3673e-27ARAD1B17160p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B17160g PE=4 SV=1
MLH2_YEAST37.63%1944e-24DNA mismatch repair protein MLH2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MLH2 PE=1 SV=1
A0A167E383_9ASCO38.85%1579e-23Mismatch repair ATPase MLH1 OS=Sugiyamaella lignohabitans GN=MLH1 PE=4 SV=1
Q6C6B8_YARLI27.69%3252e-20YALI0E10769p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E10769g PE=4 SV=1
A0A1D8PII6_CANAL27.14%4205e-20ATP-binding mismatch repair protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMS1 PE=4 SV=1
A0A1E4TDN3_9ASCO37.24%1458e-20Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147756 PE=4 SV=1
A0A1E3PP95_9ASCO25.33%3833e-19DNA mismatch repair protein MutL OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49690 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0995

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 784

Detailed signature matches

  1. Domain IPR003594
    Histidine kinase-like ATPase, C-terminal domain
    1. G3DSA:3.30.56...
    2. SSF55874 (ATPase do...)
  2. Domain IPR020568
    Ribosomal protein S5 domain 2-type fold
    1. SSF54211 (Ribosomal...)
  3. Domain IPR014721
    Ribosomal protein S5 domain 2-type fold, subgroup
    1. G3DSA:3.30.23...
  4. Domain IPR013507
    DNA mismatch repair protein, C-terminal
    1. SM01340 (DNA_mis_re...)
    2. PF01119 (DNA_mis_re...)
  5. SITE IPR014762
    DNA mismatch repair, conserved site
    1. PS00058 (DNA_MISMAT...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PF13589 (HATPase_c_3)
  2. cd00075 (HATPase_c)
  3. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. Mg2+ binding site ...
  3. G-X-G motif cd00075

Protein sequence

>MCA_01319_1
MLRASVIITTPVSIVKELVENSLDAQSSHIYVQIDSTTIGDIIVKDNGSGIDPEDRPLLAIANTTSKIKSFEDIQNTKSF
GFRGEALSAIADVAESGSNHRMVITTRTKDEKIGTVWSVDRNGEPILPYKPIAIPVGTTIKLSNLFARYPVRKKILLKEA
SKSCKAIKELLLVYSLANNQCSFELVIVSATLTRTKQVYLGHSLIQKLSNFYGIKATKHLFEGKYKDPESNKGEGVWEWE
YALPYEAYSSPMTILFNAFCINGGPMNPKNPVIRKVISKINGIVKSSVIWYISLRVPFEYYDINIEPSKDDVQFTDCDLV
MAKLELFLDRALVLRNRKLGQSEKAKVETILPTNINYLPTPDTSFEIDNEKEDDQENAGANKQEKEQGTKTFQLYKSGRI
SASINDWKTMDVLSVQPSLALNSYGMDAKEASCFLIDQHTNKNNISDAKIRKELDKIEKQEIKSNNKLENSSNCRIDQNT
KPVYMEKPSDDLYETRLIAYSPIYNYAVTAVKPALPEKPNQQSGTCIRFPLESSSSSSSFTNNVQIGKKRSSKFLENFKS
PMIDETSKLKQSRRSFSTNSFTSVNKGRVLNLTFEEISKNKTIFDFYSRKRVQQNDEYHENKALKSKQIKVNNKNDGEKF
FNIREMPPKLQINDDDDDKNNGLFNIQKWAMVANTRELRQQIETATTTTTEFRDYTRLHAKTCNITISLEKFTKYRQVTK
EAIIVRNDYKSNNNDQERAEIEKEKEKELVDVVYEMLVSKVGIFKPIREIRRHDEEKWARIEFV

GO term prediction

Biological Process

GO:0006298 mismatch repair

Molecular Function

GO:0005524 ATP binding
GO:0030983 mismatched DNA binding

Cellular Component

None predicted.