Protein
MIA_04568_1
Length
626 amino acids
Browser: contig06:381783-383748-
Protein function
EGGNOG: | 0PHQG | FG00460.1 | SIR2 family histone deacetylase |
---|---|---|---|
SGD closest match: | S000002599 | HST4 | NAD-dependent histone deacetylase HST4 |
CGD closest match: | CAL0000186930 | HST3 | NAD-dependent histone deacetylase HST3 |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_03974_1 | 63.846% | 390 | 4.25e-169 | MCA_03974_1 |
A0A0J9XBY8_GEOCN | 63.333% | 300 | 3.33e-145 | Similar to Saccharomyces cerevisiae YDR191W HST4 Member of the Sir2 family of NAD(+)-dependent protein deacetylase OS=Geotrichum candidum GN=BN980_GECA08s03321g PE=4 SV=1 |
UniRef50_A0A0J9XBY8 | 63.333% | 300 | 6.82e-142 | Similar to Saccharomyces cerevisiae YDR191W HST4 Member of the Sir2 family of NAD(+)-dependent protein deacetylase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XBY8_GEOCN |
A0A167CEB9_9ASCO | 53.804% | 368 | 1.21e-126 | Hst4p OS=Sugiyamaella lignohabitans GN=HST4 PE=4 SV=1 |
A0A060T5F6_BLAAD | 54.217% | 332 | 5.99e-123 | ARAD1B10868p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10868g PE=4 SV=1 |
Q6CB00_YARLI | 47.912% | 407 | 3.20e-115 | YALI0C23034p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C23034g PE=4 SV=1 |
A0A1E4TKK8_9ASCO | 48.344% | 302 | 1.22e-92 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_16213 PE=4 SV=1 |
HST4_YEAST | 45.695% | 302 | 1.02e-88 | NAD-dependent histone deacetylase HST4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HST4 PE=1 SV=1 |
A0A1E3PPR1_9ASCO | 35.000% | 280 | 6.26e-51 | NAD-dependent deacetylase HST3 (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_7079 PE=4 SV=1 |
HST3_CANAL | 33.007% | 306 | 5.07e-48 | NAD-dependent histone deacetylase HST3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HST3 PE=3 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0293
Protein family membership
- Sirtuin family (IPR003000)
Domains and repeats
-
Domain
1
100
200
300
400
500
626
Detailed signature matches
no IPR
Unintegrated signatures
-
-
mobidb-lite (disord...)
Protein sequence
>MIA_04568_1 MSSLPDTTPTETGATPLTSGLSTPLASVAAPTTSISRKPALPKRTLDAPDVFDMFDALHDETSHQYDRNKLRNIIHFRKP KKRPEQVSEEYDSDEEIPEEVLMASYKQDIALLHHTLRHARRIVVISGAGISVAAGIPDFRSTTGLFRLLRNEFRLKGGV SSGQQMFDASHVFSNQQALDNFHTTVCDLHSLCQKCQPTPFHELMDSISQDNRLLRLYTQNIDGLDTGLPHLGTKHPLVE PWPKTVQLHGTITSMICSKCSWTADFDPNVDNETVIEVPVTPECPECIELDGVRAVAGKRSQGVGTLRPKIVLYNEPNPD AEAIGQITEQDLLKKPDALVVVGTSLKIPGVRRMVREMSQAVHAARGCSVWMNIDDPSALSGREFESCFDLIVKGDCQIL PQMLSDYEEERRLYEEEKQAQRRTKAEARAIRQKLALEKQVATAAALIAEEDRSDSSVASRSMSEGSAASSRLTSLEPMG EVPTGATASSASTAGTGAMIAGRSKSTGVLSKRSGSRGAAAGAKRVCGGAAAAKKPRRVLGTGRKEGGAAGAKRSGKTES ARKTEPTKPALVKAGRSQSAKAGKTQSLQSGKAVKDGPSKRRKKAVPPLDEKSPNTTVPLSISVDS
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0070403 NAD+ binding
Cellular Component
None predicted.