MIA_04554_1

Protein

Length

1,900 amino acids

Protein function

EGGNOG:	0PFQZ	FG06016.1	domain protein
SGD closest match:	S000004414	YLR422W	DOCK-like protein YLR422W
CGD closest match:	CAL0000181698	DCK1	Dck1p

Protein alignments

	%id	Aln length	E-value
MCA_02886_1	76.927%	1868	0.0	MCA_02886_1
A0A0J9X7G6_GEOCN	70.027%	1885	0.0	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA04s04201g PE=3 SV=1
A0A060T669_BLAAD	56.561%	1768	0.0	ARAD1B13552p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B13552g PE=3 SV=1
UniRef50_A0A060T669	56.561%	1768	0.0	ARAD1B13552p n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A060T669_BLAAD
A0A1E3PFD1_9ASCO	43.918%	1562	0.0	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53100 PE=3 SV=1
Q6CDN9_YARLI	39.405%	1581	0.0	YALI0B22484p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B22484g PE=3 SV=1
A0A167DHR6_9ASCO	39.082%	1264	0.0	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_1212 PE=3 SV=1
A0A1D8PH11_CANAL	29.654%	1676	0.0	Dck1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DCK1 PE=3 SV=1
YL422_YEAST	24.619%	1706	2.63e-106	DOCK-like protein YLR422W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YLR422W PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0172

Protein family membership

None predicted.

Domains and repeats

Domain
201 - 533
Dedicator of cytokinesis, N-terminal domain (IPR032376)
1,433 - 1,760
Dedicator of cytokinesis, C-terminal (IPR010703)
Domain
1,366 - 1,771
DHR-2 domain (IPR027357)

1 200 400 600 800 1000 1200 1400 1600 1800 1900

Detailed signature matches

IPR032376

Dedicator of cytokinesis, N-terminal domain
1. PF16172 (DOCK_N)
  
  201 - 533
  
  Pfam
  PF16172 (DOCK_N)
IPR027357

DHR-2 domain
1. PS51651 (DHR_2)
  
  1,366 - 1,771
  
  PROSITE profiles
  PS51651 (DHR_2)
IPR010703

Dedicator of cytokinesis, C-terminal
1. PF06920 (DHR-2)
  
  1,433 - 1,760
  
  Pfam
  PF06920 (DHR-2)

no IPR

Unintegrated signatures

G3DSA:2.30.30.40

44 - 133

GENE3D
G3DSA:2.30.30.40 (G3DSA:2.30.30.40)
cd11684 (DHR2_DOCK)

1,373 - 1,762

CDD
cd11684 (DHR2_DOCK)
mobidb-lite (disord...)

1,867 - 1,900

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 30

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

dimer interface cd...

1,456K

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)

1,467Y

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)

1,469F

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)

1,470K

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)

1,472L

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)

1,473A

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)

1,476T

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)

1,477R

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)

1,479L

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)

1,480A

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)

1,483Y

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)

1,484D

dimer interface
1,456K, 1,467Y, 1,469F, 1,470K, 1,472L, 1,473A, 1,476T, 1,477R, 1,479L, 1,480A, 1,483Y, 1,484D
CDD
cd11684 (DHR2_DOCK)
Rac/Cdc42 binding ...

1,495Q

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,497F

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,521A

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,524K

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,525L

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,526G

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,527S

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,529H

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,530E

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,543S

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,544N

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,545E

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,557V

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,558S

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,559T

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,595Y

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,596S

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,597R

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,598P

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,604S

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,605P

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,608L

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,610I

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,647M

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,648L

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,651K

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,675S

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,676R

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,678D

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,679L

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,682S

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,683G

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,684A

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,687S

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,688P

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,689V

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,692G

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,693I

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,696Y

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,725Y

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,746P

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,747L

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)

1,750S

Rac/Cdc42 binding site
1,495Q, 1,497F, 1,521A, 1,524K, 1,525L, 1,526G, 1,527S, 1,529H, 1,530E, 1,543S, 1,544N, 1,545E, 1,557V, 1,558S, 1,559T, 1,595Y, 1,596S, 1,597R, 1,598P, 1,604S, 1,605P, 1,608L, 1,610I, 1,647M, 1,648L, 1,651K, 1,675S, 1,676R, 1,678D, 1,679L, 1,682S, 1,683G, 1,684A, 1,687S, 1,688P, 1,689V, 1,692G, 1,693I, 1,696Y, 1,725Y, 1,746P, 1,747L, 1,750S
CDD
cd11684 (DHR2_DOCK)
nucleotide sensor ...

1,687S

nucleotide sensor
1,687S, 1,688P, 1,689V, 1,692G
CDD
cd11684 (DHR2_DOCK)

1,688P

nucleotide sensor
1,687S, 1,688P, 1,689V, 1,692G
CDD
cd11684 (DHR2_DOCK)

1,689V

nucleotide sensor
1,687S, 1,688P, 1,689V, 1,692G
CDD
cd11684 (DHR2_DOCK)

1,692G

nucleotide sensor
1,687S, 1,688P, 1,689V, 1,692G
CDD
cd11684 (DHR2_DOCK)

Protein sequence

>MIA_04554_1
MSSSAYSVEHPTQLPLMDPPTPSPNPSIASSKALPEWSALPRIGRGVVIAKHAASPTRKNDLALNLGDEVYVFESHVSKK
WYRGYVVSPPSAHSAFNQPLPRGTKINNAALKELEPNVRIGIFPAPLVHIHEYFDLSASDAKSSLADLAKDRFSTLGGSN
LGGASDYDLEAFISGNGASASGIGASFSQLSLKSKPPPIPSIRLGNEAPTIPGEPLVDDIVSIINEWYNTYVYHHYLFGN
YELVNTINGIIQELYMIRRKLIYGLLTSNERILARKKVVWQISRVVNILNRGHVVRDAKTGDIMAGKEGPVKLAQQQILI
ALAPNYPDHSLIGDSYPEAKNPKHILVDFKSCVGQGYGHGLTVYFQLRTKSARLTEPFSIKVKPHMLVSDLSAVLFRDLP
LNITRGDVILNAELYEDVSLRSKTPTPLAIIIGKPSFTSTSNKLPKKHGRRGVASGAADVSRLFRLEDKGETPFTIRMYA
SYFSNEEPNKENRGWGELFERIVRGRPRGVAVTPRAEQVVCTVKEFEAPTVKNIEHLQNKDSHDAIGMARSLHVTSLNGE
RNDVYLTLGTISLTHIDATIPDYLLVSMTSSSGKALFSNSSNSSSYHSWDSLATYNNEVVGEMIKITDFEKSEIITFDLY
VGGEYVAQSSFPLWHGTKVWSGHKTISFVRDGDNTVATLKISVDFVGNVYNTDVAIEKILHWRMVYDSHGADELISALKK
FKTIDSKEFVKRFHGILDALLELLTTFLKSDQSELLLSIFHAIIYTLEKITNKNKDYIYLINDYLSNHLNFTGLVDLIIL
SEQALQIDTSSGRDHDIIIKMFKISEYLSQIVATSATIASGRGREAQQMIISTTRKNLKRFTETMKQVLVRQDPQFLELQ
MTIVQNIFYWYTNLRTFVPPDDELQMIIELTDSIRSDNDKLNTQRLLLIKKISASWHYQQSKYRPHITAYTIKWTLPFWL
DNREFTQERKDQIRLLSSIFATQFHTLWPVRLKEIDVCKRYGQLLPVGAKIYNELLNQFEGSANNGGRKVFSPLFPDTYP
FESRPIDSLVHNAVFDETLIELGIVLTLIVNISYNNGQQVIDNSLSTSQYSDLAFNIIHACNAMLHSVSFPKLWISLFAV
HHETVLGCLGYLSVLMKSHFIPLPEHAEDFNSGLWFSFLSCLLQLAGSEAIAVEHLPVQKRKAVWRISGDIRGRAAELLN
SMWDAIGWRSTPEDAARFDLSVFGGFQVQMFGGETSLVRDVLNLCLVRHTGAQKVAIHILHSMIVSEWTLNEDLTVIQRE
IISSLDDIFQSRGFLPEEQEKSSFSSLLRASFYSIDREDVAYPYINSLLDDVEEFLDLLLDLYNVPPGDAYNDDRIFHAL
NVLNFLKVVERVEIFSRYVNDIAEWNRSRMNYTQAGLALKLLATAYEWSYDQQLPASEYPNFPAQSGFERKEEIYEDIIQ
CFSQGKAFENAIEATKELVYAYENVSYDFKKLANTTRILAKLYDNIDTVERLAPQYFRVAYIGSGFPRSLRNRMFIFEGN
AWEKLGSIHERLHKTYPGATIVSNESQAKSEGQYLFVSTVEPDPEAKLELKYSKVKPTPGAKEYKYRLNLKRFSYSRPLP
GNTSPLDLWIEKTTYETYQSFPTIVKRSEVKNISIVKLSPLENALDMLQAKTSDLIDLETTLNSNKKGDQSSSVSRLDLV
LSGAVDSPVNGGIQLYRAFLEDEGLRADPKSAGLVASLENSFLTYASAIQRCLVIHGRVVPPTLKPLHLSLVELFHRNFA
PELTTLNDGISYIDQFRSGSLTRRVSLSAGMSLSKSGAGHRNGMIDPYGMQGHLSGGAEGGADGIRGIGIGLTEADLDDD
ESKANLDNLLGNAIAASDILIKGSDVRGDNSSLSSDGSKRSTMLMKHITRQDPSNRQIFN

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MIA_04554_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component