MCA_02886_1

Protein

Length

1,841 amino acids

RNA-seq: read pairs 10644, FPKM 71.4, percentile rank 73.1% (100% = highest expression)

Protein function

KEGG:	K05727	DOCK3	dedicator of cytokinesis protein 3
EGGNOG:	0PFQZ	FG06016.1	domain protein
SGD closest match:	S000004414	YLR422W	DOCK-like protein YLR422W
CGD closest match:	CAL0000181698	DCK1	Dck1p

Protein alignments

	%id	Aln length	E-value
MIA_04554_1	77.68%	1868	0.0	MIA_04554_1
A0A0J9X7G6_GEOCN	76.10%	1845	0.0	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA04s04201g PE=3 SV=1
A0A060T669_BLAAD	58.95%	1737	0.0	ARAD1B13552p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B13552g PE=3 SV=1
UniRef50_A0A060T669	58.95%	1737	0.0	ARAD1B13552p n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A060T669_BLAAD
A0A1E3PFD1_9ASCO	42.63%	1785	0.0	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53100 PE=3 SV=1
Q6CDN9_YARLI	39.10%	1752	0.0	YALI0B22484p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B22484g PE=3 SV=1
A0A167DHR6_9ASCO	39.94%	1267	0.0	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_1212 PE=3 SV=1
A0A1D8PH11_CANAL	29.68%	1836	0.0	Dck1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DCK1 PE=3 SV=1
YL422_YEAST	24.47%	1900	9e-111	DOCK-like protein YLR422W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YLR422W PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3177

Protein family membership

None predicted.

Domains and repeats

Domain
170 - 503
Dedicator of cytokinesis, N-terminal domain (IPR032376)
1,335 - 1,736
DHR-2 domain (IPR027357)
Domain
1,403 - 1,726
Dedicator of cytokinesis, C-terminal (IPR010703)

1 200 400 600 800 1000 1200 1400 1600 1841

Detailed signature matches

IPR032376

Dedicator of cytokinesis, N-terminal domain
1. PF16172 (DOCK_N)
  
  170 - 503
  
  Pfam
  PF16172 (DOCK_N)
IPR027357

DHR-2 domain
1. PS51651 (DHR_2)
  
  1,335 - 1,736
  
  PROSITE profiles
  PS51651 (DHR_2)
IPR010703

Dedicator of cytokinesis, C-terminal
1. PF06920 (DHR-2)
  
  1,403 - 1,726
  
  Pfam
  PF06920 (DHR-2)

no IPR

Unintegrated signatures

cd11684 (DHR2_DOCK)

1,342 - 1,727

CDD
cd11684 (DHR2_DOCK)
mobidb-lite (disord...)

1,810 - 1,841

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

dimer interface cd...

1,425K

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)

1,436L

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)

1,438F

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)

1,439K

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)

1,441L

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)

1,442A

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)

1,445T

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)

1,446R

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)

1,448L

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)

1,449A

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)

1,452Y

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)

1,453E

dimer interface
1,425K, 1,436L, 1,438F, 1,439K, 1,441L, 1,442A, 1,445T, 1,446R, 1,448L, 1,449A, 1,452Y, 1,453E
CDD
cd11684 (DHR2_DOCK)
Rac/Cdc42 binding ...

1,464Q

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,466F

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,490A

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,493K

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,494L

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,495E

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,496S

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,498H

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,499E

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,512S

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,513N

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,514E

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,526V

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,527T

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,528T

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,562F

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,563S

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,564R

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,565P

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,571S

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,572P

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,575L

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,577V

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,614L

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,615L

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,618K

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,640S

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,641R

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,643D

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,644L

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,647S

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,648G

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,649A

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,652S

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,653P

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,654V

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,657G

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,658I

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,661Y

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,690Y

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,711P

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,712L

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)

1,715S

Rac/Cdc42 binding site
1,464Q, 1,466F, 1,490A, 1,493K, 1,494L, 1,495E, 1,496S, 1,498H, 1,499E, 1,512S, 1,513N, 1,514E, 1,526V, 1,527T, 1,528T, 1,562F, 1,563S, 1,564R, 1,565P, 1,571S, 1,572P, 1,575L, 1,577V, 1,614L, 1,615L, 1,618K, 1,640S, 1,641R, 1,643D, 1,644L, 1,647S, 1,648G, 1,649A, 1,652S, 1,653P, 1,654V, 1,657G, 1,658I, 1,661Y, 1,690Y, 1,711P, 1,712L, 1,715S
CDD
cd11684 (DHR2_DOCK)
nucleotide sensor ...

1,652S

nucleotide sensor
1,652S, 1,653P, 1,654V, 1,657G
CDD
cd11684 (DHR2_DOCK)

1,653P

nucleotide sensor
1,652S, 1,653P, 1,654V, 1,657G
CDD
cd11684 (DHR2_DOCK)

1,654V

nucleotide sensor
1,652S, 1,653P, 1,654V, 1,657G
CDD
cd11684 (DHR2_DOCK)

1,657G

nucleotide sensor
1,652S, 1,653P, 1,654V, 1,657G
CDD
cd11684 (DHR2_DOCK)

Protein sequence

>MCA_02886_1
MATATSSVTTLARDQNQEWSPLPKIGRGVVVGKHVASPNRKNDITINLGDEVYVFESHISGKWYRGYVISPPSAHAAFNQ
PLPRGTKINNAALKALDPNVRSGIFPAPLIHLHEYLDLSPSDASKASSLSAAKDRFSTLAGSTDYDMESFVSGHNGISQL
GLKSKPPPIPSLRLGTEVPTVPGEPLVDDIVAVINEWYNTYVYHHYLFGNYELVNTINGIIQELYFIRRKLIYGLLTANE
RILARKKAVWQISRVINILNRGHVVRDAKTGEIMAGKEGPVKLAQEQILIALAPNYPDHSLIGDVHQEATNPKHILVDFK
SCLGQNYGHGLSVYFQLRTKSARLTEPFSIKIKPDMMVTDLSAVLFRDLPLSITRGDVILNAELYEDVPLKSKTPTSISV
ILGGKSYLPVSGKPSKKVGRRGVASGSADISRLFRIEDKGESPFTIRMYASYFGPDEPNKENRGWGELFERIVRGRPRGV
AVTPRAEQVVCTVKEFEAPTVKNIEHLQNQDSNSAIGMARSLHVTSLSGERNDIYVTLGSISLANVTSTISDFLLVSMSS
SSGKALFANSANSLAQHSWDSLATYNNEVIGEMVQITNFEKNEIVNFSLYVAGEYVAQASIPLWHGTKVWSGHKTVTFTR
ENDTIATLKIAVDFVGNVYNTDVAIEKLLHWRVVYDAHGIEELNTTLLKFKTIESKEFVKRFHDIMDALLEMLSSFLKSD
RNDLLLNIFYALIHTLEKTTSRSNDYLYLANDYMSNRFNFAGLSEILLALTDQTLQIDTSTGRDHDILIRLFKVSDFLSQ
LIAASAAIDSDRGRDAQQMVISTTRKHVKRLTETIKHVLARQDKEFVDLQMVIVQNIFSWYSNLRLYVPPDDQVQMIIEM
TDSIRNDNDKINTQRLLLIKKLSSSWHYQQSKYRPHITAYTIKWTLPFWLDPREFNQERKDQIRLLSGIFANQFHVLWPV
RHKEIDVCKRYGQLLPVGAKIYNELLSQFESNKKRSRKVFSPLFPDTYPFETRPIDSLVTDAVFDETLIELGIVLTLIVN
ISHFNGQQIIDNSLSNSQYSELAFNILQACNAMLHSVSFPKLWISLFAVHHETVLGCLSYLSILMKNQFIPLPENAEDFN
SSLWYSFLSCLLQLAGSEAIAVEHLPEQKRKAVWKISGDIRGKAAELLQTMWDAIGWPAAEEDRTRFDLDVFGGFQVQMF
GGETSLVRDVLNLCLVRHPGAQKAAIHVLRSMIVSEWTLNEDLTGLQREIIASLDDIFQSRGFLPEEQEKTSFSNLLRGS
FYNLDREDVASPYINALLDDIEEFLDLLLDLYNVPPGDAYNDDRIFHALNVLNFLKDIDRVEIFSRYVNDIAEWNRSRLH
YTQAGLALKLLGSAYDWSYDQKLSASEHPSFPAQTGFERKEAIYEDIIQCFSRGKAFENAIEATKELISAYENVSLDFKK
LANATRILAKLYESIDTVERLSPQYFRVAYVGNGFPRSLRNRLFIFEGNAWEKLESIHERLHKTYPGATIVSNESQAKQD
GQYLFVTTVEPDPENKLDLKHVHPTPGAKEYQYRLNLKRFSFSRPLPGNTSPLDLWVEKTTYETYQAFPTIVKRSEVKSV
KVVKLSPLENALQLLQGKTNDLVDFEATFKSGKTDQGNISRLDLVLSGAVDSPVNGGIQLYRAFLEDENLRSEPKSAPFV
AALENAFLDYAAAIQRCLVIHGKVVPATLKPLHLSLVELFNRNFAPELATLGEGISYAEQLRNGSLARRVSLSTNFNYNK
SGNTNGSGSMSTGTVNNDYDDTESQANLDSLLGNAIAASDILIRGSEFRDNRSVSSDGSNKRNTVIVKQNRQDTYARPIF
N

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MCA_02886_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component