Protein

MIA_04523_1

Length
547 amino acids

Browser: contig06:243081-244800+

Protein function

EGGNOG:0PGCVADE4Glutamine phosphoribosylpyrophosphate amidotransferase
SGD closest match:S000004915ADE4Amidophosphoribosyltransferase
CGD closest match:CAL0000174536ADE4Amidophosphoribosyltransferase

Protein alignments

%idAln lengthE-value
MCA_05514_184.924%5240.0MCA_05514_1
A0A0J9YHC0_GEOCN79.350%5230.0Amidophosphoribosyltransferase OS=Geotrichum candidum GN=BN980_GECA01s02199g PE=3 SV=1
A0A167FB25_9ASCO74.095%5250.0Amidophosphoribosyltransferase OS=Sugiyamaella lignohabitans GN=ADE4 PE=3 SV=1
Q6CEI8_YARLI74.953%5350.0Amidophosphoribosyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B15304g PE=3 SV=1
A0A1E4TA99_9ASCO65.597%5610.0Amidophosphoribosyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3330 PE=3 SV=1
A0A1D8PE37_CANAL67.286%5380.0Amidophosphoribosyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADE4 PE=3 SV=1
A0A1E3PP73_9ASCO67.800%5000.0Amidophosphoribosyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_73867 PE=3 SV=1
A0A060T7B6_BLAAD71.047%4870.0Amidophosphoribosyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20152g PE=3 SV=1
PUR1_YEAST66.796%5150.0Amidophosphoribosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADE4 PE=1 SV=2
UniRef50_P4139058.989%5340.0Amidophosphoribosyltransferase n=263 Tax=root TaxID=1 RepID=PUR1_SCHPO

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0225

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 500 547

Detailed signature matches

  1. Family IPR005854
    Amidophosphoribosyltransferase
    1. PIRSF000485 (Pur1)
    2. MF_01931 (PurF)
    3. TIGR01134
  2. Domain IPR029055
    Nucleophile aminohydrolases, N-terminal
    1. G3DSA:3.60.20.10
    2. SSF56235 (N-termina...)
  3. Domain IPR017932
    Glutamine amidotransferase type 2 domain
    1. PS51278 (GATASE_TYPE_2)
  4. Domain IPR035584
    Amidophosphoribosyltransferase, N-terminal
    1. cd00715 (GPATase_N)
  5. Domain IPR029057
    Phosphoribosyltransferase-like
    1. SSF53271 (PRTase-like)
  6. Domain IPR000836
    Phosphoribosyltransferase domain
    1. cd06223 (PRTases_typeI)
    2. PF00156 (Pribosyltran)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. NON_CYTOPLASM... (N...)
  3. PF13522 (GATase_6)
  4. SIGNAL_PEPTIDE (Sig...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SignalP-noTM
  9. TMhelix

Residue annotation

  1. tetramer interface...
  2. active site cd00715
  3. active site cd06223

Protein sequence

>MIA_04523_1
MIGNKYVLTVISLLCGILGLLLADPNGTASGELLEGTHFLQHRGQDAAGIVTCGPRGRFYQCKGNGMARDVFTQARVSLL
AGNMGIGHLRYPTAGSFANSEAQPFYVNSPYGIALSHNGNLVNAPALRTYLDEEVHRHINTDSDSELLLNVFAAELQNTN
KSRVNDEDIFHALAGVYERVRGAYACTAMIAGYGILGFRDPNGIRPLVMGKRTNADGTKDYMFSSESVVLQTLGFKEWFD
VKPGQAIIIPKATMEPVIRQVVPQISYTPDIFEYVYFARPDSVMDGISVYRSRLAMGDRLATNIINRFKSRHEMAKEIDV
VIPVPDTSRTSALECAVRLGIPFREGFVKNRYVGRTFIMPNQTERRSSVRRKLNAMALEFSGQNVLLVDDSIVRGTTSKE
IVQMAREAGAKKVYFASCAPPIRHNHIYGIDLADTKALVAYNKTEEEISKAIGADAVYYQTLEDLVKACSSPGDEETGTP
KINEFEVGVFTGEYVTGVEQSYLDYLETIRGQNQRLKEQERHGIASILEDPKAEVDIGLFNHGDIVV

GO term prediction

Biological Process

GO:0009113 purine nucleobase biosynthetic process
GO:0009116 nucleoside metabolic process

Molecular Function

GO:0004044 amidophosphoribosyltransferase activity

Cellular Component

None predicted.