Protein

MIA_04518_1

Length
374 amino acids


Browser: contig06:232227-233352+

Protein function

EGGNOG:0PKB4FG05133.1DnaJ domain protein
SGD closest match:S000004952SIS1Protein SIS1
CGD closest match:CAL0000193586SIS1Type II HSP40 co-chaperone

Protein alignments

%idAln lengthE-value
A0A1E3PLX5_9ASCO36.364%1761.30e-31Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_22403 PE=4 SV=1
A0A0J9X7A0_GEOCN37.500%1761.19e-28Similar to Saccharomyces cerevisiae YNL007C SIS1 Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p OS=Geotrichum candidum GN=BN980_GECA04s03189g PE=4 SV=1
MCA_02315_135.429%1754.73e-28MCA_02315_1
A0A167FR71_9ASCO34.857%1753.48e-27Type I HSP40 co-chaperone YDJ1 OS=Sugiyamaella lignohabitans GN=YDJ1 PE=4 SV=1
A0A060T3K1_BLAAD36.571%1757.70e-27ARAD1C34166p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C34166g PE=4 SV=1
Q59V92_CANAL33.143%1751.49e-26Type II HSP40 co-chaperone OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SIS1 PE=4 SV=1
UniRef50_Q0991236.000%1751.67e-22Protein psi1 n=7 Tax=Ascomycota TaxID=4890 RepID=PSI1_SCHPO
Q6C608_YARLI35.795%1761.46e-25YALI0E13508p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E13508g PE=4 SV=1
A0A1E4TF62_9ASCO31.429%1753.40e-21Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2140 PE=4 SV=1
SIS1_YEAST31.250%1761.24e-19Protein SIS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SIS1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0175

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 374

Detailed signature matches

    1. PF00226 (DnaJ)
    2. SM00271 (dnaj_3)
    3. PS50076 (DNAJ_2)
    4. SSF46565 (Chaperone...)
    5. cd06257 (DnaJ)
    6. PR00625 (JDOMAIN)
    1. SSF49493 (HSP40/Dna...)
    1. PF01556 (DnaJ_C)
    1. PS00636 (DNAJ_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd10747 (DnaJ_C)
  2. mobidb-lite (disord...)

Residue annotation

  1. HSP70 interaction ...
  2. substrate binding ...
  3. dimer interface cd...

Protein sequence

>MIA_04518_1
MSRHTDLYRILNLDPDASQDDIKRAYKTLVRIYHPDRNTSSSSHEEFIRIRGAYDTLSNVNTRALYDLYGRVVEPRRQES
EEEQEYDNRPQYNGTTAAPTPETPRTSTQYSYTFNSPRESRRTSTGSSSRGSTSYSYTFSHGEGNTYDPRPPSSRYSETF
SSSRSSPQSMSSDQTSPTSNQNTNQNSNNSPPSTNTQQLVTLKLTLAELYNGCTRVEQVERRDHRGTTTQYPFRIEIKPG
TKSGTTVIFKQAGSYNSSMGTWQDLVFVCAEEDGGPTALFSRQNNDLHMSLVVSLRAAMTGIDRVITLPGGKEHQIKVDT
PVQTGHKVKYLGLGFVKDPLMQVQERGNLIVHFKVKKPSELTPAQRKAIEKHFE

GO term prediction

Biological Process

GO:0006457 protein folding

Molecular Function

GO:0051082 unfolded protein binding

Cellular Component

None predicted.