Protein
MCA_02315_1
Length
369 amino acids
Gene name: SIS1
Description: HSP40 co-chaperone, DnaJ homolog
Browser: contigB:919298-920408-
RNA-seq: read pairs 1990, FPKM 66.5, percentile rank 71.4% (100% = highest expression)
Protein function
| Annotation: | SIS1 | HSP40 co-chaperone, DnaJ homolog | |
|---|---|---|---|
| KEGG: | K09510 | DNAJB4 | DnaJ homolog subfamily B member 4 |
| EGGNOG: | 0PKB4 | FG05133.1 | DnaJ domain protein |
| SGD closest match: | S000004952 | SIS1 | Protein SIS1 |
| CGD closest match: | CAL0000193586 | SIS1 | Type II HSP40 co-chaperone |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00845_1 | 64.63% | 393 | 5e-150 | MIA_00845_1 |
| A0A167FR71_9ASCO | 58.06% | 372 | 4e-120 | Type I HSP40 co-chaperone YDJ1 OS=Sugiyamaella lignohabitans GN=YDJ1 PE=4 SV=1 |
| A0A060T3K1_BLAAD | 55.15% | 379 | 1e-116 | ARAD1C34166p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C34166g PE=4 SV=1 |
| A0A0J9X7A0_GEOCN | 69.04% | 239 | 4e-108 | Similar to Saccharomyces cerevisiae YNL007C SIS1 Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p OS=Geotrichum candidum GN=BN980_GECA04s03189g PE=4 SV=1 |
| Q59V92_CANAL | 51.60% | 376 | 4e-107 | Type II HSP40 co-chaperone OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SIS1 PE=4 SV=1 |
| UniRef50_A0A1A0H9D8 | 53.51% | 370 | 5e-100 | DnaJ-domain-containing protein n=4 Tax=saccharomyceta TaxID=716545 RepID=A0A1A0H9D8_9ASCO |
| A0A1E4TF62_9ASCO | 49.75% | 394 | 8e-100 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2140 PE=4 SV=1 |
| Q6C608_YARLI | 55.17% | 232 | 4e-81 | YALI0E13508p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E13508g PE=4 SV=1 |
| A0A1E3PLX5_9ASCO | 52.96% | 253 | 3e-77 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_22403 PE=4 SV=1 |
| SIS1_YEAST | 44.58% | 249 | 5e-59 | Protein SIS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SIS1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1205
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
1
50
100
150
200
250
300
369
Detailed signature matches
no IPR
Unintegrated signatures
-
-
cd10747 (DnaJ_C)
-
mobidb-lite (disord...)
Residue annotation
-
HSP70 interaction ...
-
substrate binding ...
-
dimer interface cd...
Protein sequence
>MCA_02315_1 MVKETKLYDLLGVKPDASDNEIKKGYRKMALKYHPDKPTGDTEKFKEISEAFDILSNSDKRQVYDMYGLEAARHGGPMPD PDAGAAGGFPGGAGGAGGFPGGFPGGAGGNPFVFSTGGPGGAKTFSFSTSGGGGNPFHAFSANDAFNIFSHFTQSEGLGS DDDDIFSMPRSKSSFGGFGGSSGGGGARRQRSPPREKSTVKVNLPLSLEDLYSGTTKKMKIRRRLANGQSEERILNISVK PGWKAGTKITYPNEGDYQPDGSIQDVIFVVEEKPHPRFKRVDNNLEMDLRISFKEAMLGFSKIVETLDGKKIKIENKSPI SPGHVITYPGHGMPISKKPGTKGDLIITIKVDFPTKLTESQRKAIEENF
GO term prediction
Biological Process
GO:0006457 protein folding
Molecular Function
GO:0051082 unfolded protein binding
Cellular Component
None predicted.