Protein

MIA_04513_1

Length
416 amino acids

Browser: contig06:223949-225200-

Protein function

EGGNOG:0PIQJRTT109DNA damage response protein
SGD closest match:S000003925RTT109Histone acetyltransferase RTT109
CGD closest match:CAL0000176178RTT109Histone acetyltransferase RTT109

Protein alignments

%idAln lengthE-value
MCA_00802_139.773%4401.98e-97MCA_00802_1
A0A0J9XJJ8_GEOCN44.324%3702.87e-94Similar to Saccharomyces cerevisiae YLL002W RTT109 Histone acetyltransferase critical for cell survival in the presence of DNA damage during S phase OS=Geotrichum candidum GN=BN980_GECA19s01198g PE=4 SV=1
UniRef50_A0A0J9XJJ844.324%3705.86e-91Similar to Saccharomyces cerevisiae YLL002W RTT109 Histone acetyltransferase critical for cell survival in the presence of DNA damage during S phase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJJ8_GEOCN
A0A060SYU9_BLAAD36.250%4006.58e-69ARAD1C03762p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C03762g PE=4 SV=1
A0A167EUD1_9ASCO33.744%4066.82e-56H3 histone acetyltransferase RTT109 OS=Sugiyamaella lignohabitans GN=RTT109 PE=4 SV=1
Q6C1H1_YARLI37.201%2934.96e-39YALI0F16313p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F16313g PE=4 SV=1
A0A1E4TCH6_9ASCO32.759%2321.98e-33Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_139735 PE=4 SV=1
A0A1E3PKW3_9ASCO31.128%2577.75e-29Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82926 PE=4 SV=1
RT109_YEAST24.854%3422.32e-24Histone acetyltransferase RTT109 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RTT109 PE=1 SV=1
RT109_CANAL23.385%3251.76e-17Histone acetyltransferase RTT109 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RTT109 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0314

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

  1. Family IPR013178
    Histone acetyltransferase Rtt109/CBP
    1. PF08214 (HAT_KAT11)
    2. SM01250 (KAT11_2)
  2. Family IPR016849
    Histone acetyltransferase Rtt109
    1. PS51728 (RTT109_HAT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)

Protein sequence

>MIA_04513_1
MKNTRQAILEELAAGLPEAVDKFDVIWYQTRPAKVRPLVYRRPKRTKAQGGAATPAYAQYSAKSDPDLSSRALVVVMYRG
LIIYAIEMFLYAMPGDQGMQTLFVSKADTTGHYVLTETDGDKPRPKLSYAKLTEGILRGVLRSYVDPKAPVRLCLFARAE
KHYLFPYSGDAAAVAAGRKHVATGSELVRWWVRVLDEVCRDTRVVAKVGRARVQIPGAEAARIRGGYLPKRPEGVEWQVG
DVFWPEGRGDLGAIRCVPRFPDDPLTRYVDDLVTAGRSTRTGQRVFWAELEARQEFRLGIVVGVIGVELWVNGESSVYGS
NEGDIPETSMWELNRVYEYISTLDYAETEMNGAAAKYLLGQTADEGSSAPSRHLVVKGTLRVEEKKQGSDGVESGSVSTP
NVLGGMLIRKKKKKKV

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated
GO:0016573 histone acetylation
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress

Molecular Function

GO:0004402 histone acetyltransferase activity
GO:0010484 H3 histone acetyltransferase activity

Cellular Component

GO:0005634 nucleus