Protein

MCA_00802_1

Length
589 amino acids


Gene name: RTT109

Description: Histone acetyltransferase RTT109

Browser: contigA:2501696-2503466-

RNA-seq: read pairs 965, FPKM 20.2, percentile rank 41.7% (100% = highest expression)

Protein function

Annotation:RTT109Histone acetyltransferase RTT109
KEGG:K11309RTT109 regulator of Ty1 transposition protein 109
EGGNOG:0PIQJRTT109DNA damage response protein
SGD closest match:S000003925RTT109Histone acetyltransferase RTT109
CGD closest match:CAL0000176178RTT109Histone acetyltransferase RTT109

Protein alignments

%idAln lengthE-value
MIA_04513_140.00%4401e-101MIA_04513_1
A0A0J9XJJ8_GEOCN39.16%4294e-88Similar to Saccharomyces cerevisiae YLL002W RTT109 Histone acetyltransferase critical for cell survival in the presence of DNA damage during S phase OS=Geotrichum candidum GN=BN980_GECA19s01198g PE=4 SV=1
UniRef50_A0A0J9XJJ839.16%4298e-85Similar to Saccharomyces cerevisiae YLL002W RTT109 Histone acetyltransferase critical for cell survival in the presence of DNA damage during S phase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJJ8_GEOCN
A0A060SYU9_BLAAD35.59%3548e-58ARAD1C03762p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C03762g PE=4 SV=1
A0A167EUD1_9ASCO34.63%3611e-54H3 histone acetyltransferase RTT109 OS=Sugiyamaella lignohabitans GN=RTT109 PE=4 SV=1
Q6C1H1_YARLI31.31%3137e-36YALI0F16313p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F16313g PE=4 SV=1
A0A1E4TCH6_9ASCO27.24%3235e-31Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_139735 PE=4 SV=1
A0A1E3PKW3_9ASCO31.85%3142e-28Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82926 PE=4 SV=1
RT109_YEAST38.37%1726e-28Histone acetyltransferase RTT109 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RTT109 PE=1 SV=1
RT109_CANAL32.40%1792e-17Histone acetyltransferase RTT109 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RTT109 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0320

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF08214 (HAT_KAT11)
    2. SM01250 (KAT11_2)
    1. PS51728 (RTT109_HAT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_00802_1
MTEKKEPSFAYEVLTEELLKCLPKTDLPFNVLFYKTNPVKCRRPLIYRKPPKKTRPKDYNVADDTDYLTTYFVVLTYNNL
MIYAIEILVYDYPKHEQTLFVSKADTTGHYGLENADSERSQSLNKDVKPTSTNPNEQSNKDDEIKTEEKEEEEKKFKDIK
MNSQPPKVSFAAVTQAILKTIIRCFIDPSRPLHLNLFARAEKHYLFPYSADDKRKHVQTGAELVKWWINVLDNVCAPPTD
EDDDNSIIEKVERARLQIPGSEAPRIRSYFPDRQKPYITNKTLTEKELKRRNDFFTWQVGDIFWPDNDPNLAAVRCVPRF
FDDPLTRYIEFLAEEKRATKTTQRIFWIELETRQEFRLSIVVGVIGIECKVCEKRSLYKKLNSKKRSNNDNNNNNNNNSD
IQSITQWDMKSIHDYITTLDYGDVKMNTAATKMLLQMANIPSKEKRSISLAENDKKEDEEEKSKTRNSESVFKIKSNWGS
KLEIYGQYVKQDDGLPKNDNNNNPDGKTSAENIITVTTTDNKPINMLNTGMMVRKKPKRANVTTISSSSPSSFSASNNVT
TDKSTNTTQQEGVTTLNSNLIRKKPKLNN

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated
GO:0016573 histone acetylation
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress

Molecular Function

GO:0004402 histone acetyltransferase activity
GO:0010484 H3 histone acetyltransferase activity

Cellular Component

GO:0005634 nucleus