Protein

MIA_04447_1

Length
1,064 amino acids


Browser: contig06:60156-63351-

Protein function

EGGNOG:0PGHVLOS1tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre- tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity)
SGD closest match:S000001688LOS1Exportin-T
CGD closest match:CAL0000200169LOS1Exportin-T

Protein alignments

%idAln lengthE-value
MCA_06358_160.916%11130.0MCA_06358_1
A0A0J9XJ75_GEOCN57.914%10740.0Similar to Saccharomyces cerevisiae YKL205W LOS1 Nuclear pore protein involved in nuclear export of pre-tRNA and in re-export of mature tRNAs after their retrograde import from the cytoplasm OS=Geotrichum candidum GN=BN980_GECA20s00923g PE=4 SV=1
UniRef50_A0A0J9XJ7557.914%10740.0Similar to Saccharomyces cerevisiae YKL205W LOS1 Nuclear pore protein involved in nuclear export of pre-tRNA and in re-export of mature tRNAs after their retrograde import from the cytoplasm n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJ75_GEOCN
A0A060SZE2_BLAAD47.589%10990.0ARAD1C06842p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06842g PE=4 SV=1
A0A1E3PDK1_9ASCO45.247%10940.0Xpo1-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53565 PE=4 SV=1
A0A167C7Y1_9ASCO42.463%10150.0Los1p OS=Sugiyamaella lignohabitans GN=LOS1 PE=4 SV=1
XPOT_YARLI38.038%10910.0Exportin-T OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=LOS1 PE=3 SV=1
A0A1E4TM73_9ASCO37.827%9573.07e-170Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_14808 PE=4 SV=1
XPOT_CANAL31.401%11211.78e-141Exportin-T OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LOS1 PE=3 SV=1
XPOT_YEAST26.736%11521.52e-90Exportin-T OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LOS1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0765

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1000 1064

Detailed signature matches

    1. SSF48371 (ARM repeat)
    1. PF08389 (Xpo1)

Protein sequence

>MIA_04447_1
MEDRLELAVNTALSGSSNLKQEAIEYCNLIKNSPDGWKTGLALFTDATTQRSDTARFFSLQIVDAALPTLQPSDLTSVKS
SIFSYIIKSLDSSLQSPSQPSPFGESFLRNKLAQTLSYLFILTYNSSIWPSFFDDLIATLSPPAFANSRAVDLYLRVLLA
VHAEIGDNLIVRDQETTKRNNILKDLIRDRAVSKLAQSWLQILQAYSKNDDKDSQTIKDSCLKVIGGWVSWIDITLIVNP
LYLQTIFSFLSNTSSHKLTTCDTLLEIISKKMKPADKLELLQLLDLKNIISQLSNNQDLELEERLAKLSNVVVIELVHIL
DGSTSTAARVPLTPDVSQKAEALLIEFMPTIIHYLSNEYDDTSSQVFPCIGEYLAFVRTESKQAKANVDTSKMQRNKDTG
YIADFPPDSTFISSTRREILQLLLSKIIVKMRYDTDASWTDDEDESETEFLDIRNRLKILQDQIASIDMDLYIDGIVSIV
TTSFVPSAVSSWQDVELGLFELSAYSESLRNGAVAVVKGVETRASRTLYELFFKMIESNVVLTNHPSIQLHYMELVNRHS
MFFSSSNSDALAKVLECFVSSFGIHNSTRRVQVRAWYLFFRFIKSVRGILRANVAEMVFTSIQSSLLQIKAEIPPKDDES
EVSGSEASGAGFFNSQLYLFELCGLLLSNHHKRDAAASSTNDEFSTVVDNKKQLLLTHSLLQPIYNDIEQNLSKPEDDTL
AALQVHHDIMAIGTFARGFNEVGTAASSNSDTVHNGMDAQVAEEFRTATRVVITSLERMGRAEVIRDGARFAISRLIPVL
GSSILNEVTRLISCLLELSKLEELADFLGFLGQLVHNFRQEPGVYDMFDTLMVPLFSRISSALTKADQEAVASGGSTDAR
ILKRELRRAYLTFLYNLLNNGMGSILFSPTNAPKIYEPVLQSLLIYSADVEGDSGSAKVAILCLNKMLQIWGTGENTQEG
KPVPGFKEFTLQHISRITWEIPTRLGFNTRDAQMRALLGDLALVQREIYSKYGDVYAQFLQTQYLPSIGLPGEYISEYIQ
NLQGQNIKQFKVFYIQMISALTNK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005488 binding

Cellular Component

None predicted.