Protein
MCA_06358_1
Length
1,096 amino acids
Gene name: LOS1
Description: Exportin-T
Browser: contigD:3981121-3984503-
RNA-seq: read pairs 2573, FPKM 29.0, percentile rank 51.7% (100% = highest expression)
Protein function
| Annotation: | LOS1 | Exportin-T | |
|---|---|---|---|
| KEGG: | K14288 | XPOT | exportin-T |
| EGGNOG: | 0PGHV | LOS1 | tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre- tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity) |
| SGD closest match: | S000001688 | LOS1 | Exportin-T |
| CGD closest match: | CAL0000200169 | LOS1 | Exportin-T |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04447_1 | 59.71% | 1112 | 0.0 | MIA_04447_1 |
| A0A0J9XJ75_GEOCN | 52.98% | 1106 | 0.0 | Similar to Saccharomyces cerevisiae YKL205W LOS1 Nuclear pore protein involved in nuclear export of pre-tRNA and in re-export of mature tRNAs after their retrograde import from the cytoplasm OS=Geotrichum candidum GN=BN980_GECA20s00923g PE=4 SV=1 |
| UniRef50_A0A0J9XJ75 | 52.98% | 1106 | 0.0 | Similar to Saccharomyces cerevisiae YKL205W LOS1 Nuclear pore protein involved in nuclear export of pre-tRNA and in re-export of mature tRNAs after their retrograde import from the cytoplasm n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJ75_GEOCN |
| A0A060SZE2_BLAAD | 46.39% | 1123 | 0.0 | ARAD1C06842p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06842g PE=4 SV=1 |
| A0A1E3PDK1_9ASCO | 43.01% | 1116 | 0.0 | Xpo1-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53565 PE=4 SV=1 |
| XPOT_YARLI | 34.11% | 1120 | 0.0 | Exportin-T OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=LOS1 PE=3 SV=1 |
| A0A167C7Y1_9ASCO | 46.13% | 568 | 2e-148 | Los1p OS=Sugiyamaella lignohabitans GN=LOS1 PE=4 SV=1 |
| A0A1E4TM73_9ASCO | 35.12% | 991 | 2e-140 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_14808 PE=4 SV=1 |
| XPOT_CANAL | 34.39% | 695 | 9e-89 | Exportin-T OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LOS1 PE=3 SV=1 |
| XPOT_YEAST | 24.24% | 1192 | 2e-77 | Exportin-T OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LOS1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0268
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
1
100
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300
400
500
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700
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1096
Detailed signature matches
no IPR
Unintegrated signatures
-
mobidb-lite (disord...)
Protein sequence
>MCA_06358_1 MEDKLEIAVNTALSGSNDLKQEAIQFCNSIKDSPDGWKTGLSLLVQGSKRSDPSRFFSLQVVDSWLPRLSQSDLDVAKTS LFNYISSTTSSDDVASFGEPFLRNKLAQTLSYVFILTYESTWSSFFNDFLSLLSTAQGGPVSNAKAVDIYLRVLNNIHVE IGDTLILRDTDTIKRNNVLKDLIRDRDISKLTDSWQQILVYYSQQQNSSSANQRSISEIIDNCLKVIGGWVLWVDITLIV NPSYLNSIFSFFQSPDHRLSTCDTILEIISKKMKPADKLDLIKLLDLGNISASSDDPEFEERVAKLCNAVAIEIIHILDG STSASSKVPVTQDIFESAEAFLVNFFPKIIYFLSNEFDDTSCQVLPCISEYLGFVRMQSKQAKDQYDTSQLKRHRETGTF LDFPPDSQFIPATRMEILSTLLSQVIRKMKYDPDSDWTGGEDESESEFLDIRAKLKVIQDQIASIDMDLYTDGIASVVTS SLSNPSSWQDAELGLYELSAFSESLKNGAISVIKGIESRPSKVLYELFFKMIESNIVVMNHPSIQLHYMELVNRHCMFFS SSNMEALGKVFEAFVSPLGIHNGNTRVQVRSWYLFYRFVKSVRSLLRPDIIETIYTSVQPLLQIKAELPEKDEDEEEISG EKAAGAGTFDSQLYLFELCGLLLSNHRVSSATTNTSDVNSNGGNKNKSLMNSSNNDPNNDKNNNNTNNNTHSQTLLSPQI QLQLMQGLLQPIYRDVEAILQNGSLDQLASLQVHHDLMAIGTFSRGFNDISTNVSSNSDSISNAVNMDPQIANEFNIATQ VVITSLERMGRAEVIRDAARFSISRIIPVLGAKILPDVTRLISCLLESSKLHEWVDFWGFLGQLAHNFKREAGIYDMFDT LMTPLFAKATDVLKQAESEASGGSTDAIILKRSLRKGFLALLYNLLNNGLGALLFSKNNISIYEPILELLLVYSADVQAD SDSAKVAILILNKMLLVWGNGTVKEDQYQAGASVPGFEQFTLQHISRITWEIPTKPNFNPRDAQMRGILGDLATVQQAIQ NVYKDMYVQFLAEQYLPSIGLPQEYINEYLNKLSNANPKQFKSFYIQLITSLVSKN
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0005488 binding
Cellular Component
None predicted.