Protein

MIA_04437_1

Length
639 amino acids

Browser: contig06:545-2635+

Protein function

EGGNOG:0QDZFReverse transcriptase (RNA-dependent DNA polymerase)
SGD closest match:S000007354TY2B-OR1Transposon Ty2-OR1 Gag-Pol polyprotein
CGD closest match:CAL0000201372orf19.2372Uncharacterized protein

Protein alignments

%idAln lengthE-value
UniRef50_A0A0J7MUL538.034%2343.61e-43Retrovirus-related pol polyprotein from transposon tnt 1-94 (Fragment) n=1 Tax=Lasius niger TaxID=67767 RepID=A0A0J7MUL5_LASNI
MCA_01665_152.941%1024.19e-27MCA_01665_1
A0A161HJI4_9ASCO28.571%1961.43e-16Gag-pol fusion protein OS=Sugiyamaella lignohabitans GN=AWJ20_4398 PE=4 SV=1
YO21B_YEAST26.190%2523.36e-13Transposon Ty2-OR1 Gag-Pol polyprotein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TY2B-OR1 PE=3 SV=1
A0A1D8PR73_CANAL28.571%1051.41e-07Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2372 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6688
Predicted cleavage: 13

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 639

Detailed signature matches

  1. Domain IPR012337
    Ribonuclease H-like domain
    1. SSF53098 (Ribonucle...)
    2. G3DSA:3.30.42...
  2. Domain IPR001584
    Integrase, catalytic core
    1. PF00665 (rve)
    2. PS50994 (INTEGRASE)
  3. Domain IPR013103
    Reverse transcriptase, RNA-dependent DNA polymerase
    1. PF07727 (RVT_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)
  5. mobidb-lite (disord...)

Protein sequence

>MIA_04437_1
MRRLLGRQSNIIAVHWYHGKSHSTVGITCVGLERTSCCYPVGHRYVLTIMDFYSRYSYVELLVKKSDASLAIRNYIARCE
SYFSGDSRGNRVSYFHSDNGGEYISKDLEQFFVSKGIKHTFTVPHTPQQNGVAERLNRTLFEKAKSMLLYSHAPDYLWGE
AVKCANYLRNRLPSRTTGGVCLLQLWTGKPPSYQHMRVFGCRANVVVADAKRESKLSSNIDPGVFVGYSLDRTAYRVLVD
SSIVEARDVYFDESQFPFMKNDKELSSNGSGIAFGIGCGSGSMSGPRADCNDSVRVLVLGLVGLYLTSLLVLDLVLVRLA
HLVLLVPLRLVRRRRRCRRLRRCLRLSFFVSLVVHKPRSVRRILPSSSAPLESPTLPSLPSSPILPTSDQDPSVSSPIGP
SRSDLLQVGSPAGESDNSGDSGIRNEGRVSVDTKDDTQAILPKSRSRVVAVRLPSVTPAKRPSSHDFVAPPSKHRCDDSA
KLAASSVVPAKRRAEEESISYRRLKSLRFEYDDVALLVFTDPTTFEQAMSSEDAEFWLEACVLEMSSLKRNRTWDLVDLP
PGRKAINSKWVFKIKRKADGSIERYKARLVCIGFSQVEGIDYTETFAPVVRYETVRIVLAIAAQFGFQVHHMDVETVEL

GO term prediction

Biological Process

GO:0015074 DNA integration

Molecular Function

GO:0003676 nucleic acid binding

Cellular Component

None predicted.