Protein

MIA_04420_1

Length
1,004 amino acids

Browser: contig05:1657936-1660951+

Protein function

EGGNOG:0PHKGMNL1hydrolase family 47 protein
SGD closest match:S000001247MNL1ER degradation-enhancing alpha-mannosidase-like protein 1
CGD closest match:CAL0000199621orf19.834alpha-1,2-Mannosidase

Protein alignments

%idAln lengthE-value
MCA_00755_156.015%7980.0MCA_00755_1
A0A0J9X2U9_GEOCN50.066%7550.0alpha-1,2-Mannosidase OS=Geotrichum candidum GN=BN980_GECA01s05653g PE=3 SV=1
UniRef50_A0A0J9X2U950.066%7550.0alpha-1,2-Mannosidase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X2U9_GEOCN
A0A167E7G0_9ASCO60.941%4890.0alpha-1,2-Mannosidase OS=Sugiyamaella lignohabitans GN=MNL1 PE=3 SV=1
A0A060TEE6_BLAAD55.750%5130.0alpha-1,2-Mannosidase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D14608g PE=3 SV=1
A0A1E3PNG0_9ASCO57.500%4800.0alpha-1,2-Mannosidase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_8473 PE=3 SV=1
A0A1E4TLJ1_9ASCO50.216%4629.50e-162alpha-1,2-Mannosidase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1221 PE=3 SV=1
Q6C995_YARLI49.160%4761.45e-155alpha-1,2-Mannosidase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D12925g PE=3 SV=1
MNL1_YEAST43.542%4801.00e-128ER degradation-enhancing alpha-mannosidase-like protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MNL1 PE=1 SV=1
A0A1D8PH01_CANAL42.661%5114.61e-118alpha-1,2-Mannosidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.834 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0499

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 1004

Detailed signature matches

  1. Family IPR001382
    Glycoside hydrolase family 47
    1. PR00747 (GLYHDRLASE47)
    2. PF01532 (Glyco_hydr...)
    3. SSF48225 (Seven-hai...)
  2. Domain IPR015943
    WD40/YVTN repeat-like-containing domain
    1. G3DSA:2.130.1...
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. G3DSA:1.50.10.10
  4. NON_CYTOPLASM... (N...)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)
  7. mobidb-lite (disord...)

Protein sequence

>MIA_04420_1
MRVPPLVYHGIYVVMAVLVASTAAAASVAASFMDFTPDTLDQLAAGARDMFYHGWSNYLRNAFPDDELRPLTCDGLSRDE
ADPTNIGVNDVLGAYSVTLIDALDMFPILGDQQGFERNVERVRKYVSFNVSSTVQVFETTIRAMGGLLSAHLYASTPRLG
HKIPNYDGFLLDLAYDLAERLLPSFNSPSGIPYPRINLKYGLQPKIYPGNITETCTSGAGSLVLEFGLLSRLTGDYRFEI
AAKRAFFALWQRRSNLDLVPMAVDAESGVWLAPMTGVGASIDSYYEYAIKYHVLFTSPDFLSVFNRAHHALLSHSFDGWL
FHNVNFERGSTVTSWIDSLAAFYPSIMVLGGDLENAVRAHLAYYKIWNTYSAIPERWYAIPRVYSSRFTAESAVNLEWYP
LRPEFIESNYYIYKATKDPLFLQIGKSAMEDLQLRNKVECGYAGTQNVKTGQLSNRMESFFLSETTKYLYLLFNQSHPLN
KEYSNSVFSTEAHPFWYDKDIMEHAGAQNFELLRRVWNKNHSPPATKPDITKEQAKLLREMLDNEDMPWYKKMSLSMLWG
DYRNSFEKRHHKSLLVRIMRKLLYYIKTINYRIDSYIMPRFIDYITKKNEQSTQQQRQQHQRILATLPIKPTKVPVSNIH
KASGVKNQHQHLHTRPPAYFYNNQCEVWRPYSVMYSDSSVRAGMASALQIQTGMYSPIASSPQFFQLDRMYMYKRPRHLR
KYISFENRAGFWDRYVIPEGQCLAQTAEAPALGPPAQNAGEVEIMFMLQEGTQRGSVLLRYANGTVEATNLNGMRIKLRE
RGSEEEEMEKEKDIECKEDEIYNEEDENNDENDEDNEEIGDQDQNYINDKFDGQEEEEGDDDDEDNDDDYDYDDDDDDDD
DDDDDDDDDEDNDDNDNDNNNDNNNNNNNNNDNNNDNNNDDNEDDDGDDDEEDEDYQIQSSTKNIPSPASPLYDIVVIDG
IRIPKRLRLQNLWLSRGVIELTSHGRVRIQNFTIENLDVTNLYS

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding

Cellular Component

GO:0016020 membrane