Protein

MIA_04418_1

Length
612 amino acids

Browser: contig05:1653442-1655281-

Protein function

EGGNOG:0PGEGGUT2Glycerol-3-phosphate dehydrogenase
SGD closest match:S000001417GUT2Glycerol-3-phosphate dehydrogenase, mitochondrial
CGD closest match:CAL0000181855GUT2Glycerol-3-phosphate dehydrogenase

Protein alignments

%idAln lengthE-value
MCA_01332_175.556%6300.0MCA_01332_1
A0A0J9X5P8_GEOCN74.953%5270.0Glycerol-3-phosphate dehydrogenase OS=Geotrichum candidum GN=BN980_GECA03s02771g PE=3 SV=1
UniRef50_A0A0J9XGN072.021%5790.0Glycerol-3-phosphate dehydrogenase n=9 Tax=Opisthokonta TaxID=33154 RepID=A0A0J9XGN0_GEOCN
Q6CEQ0_YARLI68.729%5820.0Glycerol-3-phosphate dehydrogenase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B13970g PE=3 SV=1
A0A167DSI3_9ASCO67.077%5680.0Glycerol-3-phosphate dehydrogenase OS=Sugiyamaella lignohabitans GN=GUT2 PE=3 SV=1
A0A060SZJ8_BLAAD65.961%5670.0Glycerol-3-phosphate dehydrogenase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C05346g PE=3 SV=1
A0A1E3PQP2_9ASCO62.395%5930.0Glycerol-3-phosphate dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48430 PE=3 SV=1
A0A1E4TKZ4_9ASCO54.610%5640.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30577 PE=4 SV=1
GPDM_YEAST47.504%6213.38e-175Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GUT2 PE=1 SV=2
A0A1D8PMP1_CANAL48.161%5981.98e-160Glycerol-3-phosphate dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GUT2 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9307
Predicted cleavage: 32

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 612

Detailed signature matches

  1. Family IPR000447
    FAD-dependent glycerol-3-phosphate dehydrogenase
    1. PR01001 (FADG3PDH)
    2. PS00978 (FAD_G3PDH_2)
    3. PS00977 (FAD_G3PDH_1)
  2. Domain IPR023753
    FAD/NAD(P)-binding domain
    1. G3DSA:3.50.50.60
    2. SSF51905 (FAD/NAD(P...)
  3. Domain IPR006076
    FAD dependent oxidoreductase
    1. PF01266 (DAO)
  4. Domain IPR031656
    Alpha-glycerophosphate oxidase, C-terminal
    1. PF16901 (DAO_C)
  5. SITE IPR006311
    Twin-arginine translocation pathway, signal sequence
    1. PS51318 (TAT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SSF54373 (FAD-linke...)
  7. TMhelix

Protein sequence

>MIA_04418_1
MFASRRSLVWTTSAAAAALAGAAIYNSTTRAHAQSKLLSYEDKHVIPPAPALAPPSRKDLLSKLNSEYDIVVVGGGATGT
GIAVDAASRGLKVALLERDDFSSGTSSRSTKLVHGGVRYLEKAVWNLDYNQYQLVREALHERKVFLDIAPHLSFALPIMI
PVYTWWQLPYFWVGTKCYDLLAGKQNLESSYLLTRSKALEAFPQLNSDTLKGAIVYYDGSHNDSRMNVSLAVTAAEMGAT
VLNHVEVTGLEKDAEGKIVGVKAKDLNGELAEEVSIRAKSVINATGPFTDAIRKFDEPSVREIVAPSSGVHIVLPGFYSP
KRMGLLDAATSDGRVIFFLPWQGSTIAGTTDSPSPISANPIPSEQDIEFILKEVSKYFEGKLDVRREDVLAAWSGIRPLV
RDPKAKNTESLVRNHLITVSDSGLLTIAGGKWTTYRQMAQEAVDEAITIGKLEPPVPKTATETLKLVGADQWSPLQYIHL
AQKYALDPEVARHLSENYGTRAYTIAESLKEANPPASSTHSVVTATRGTRLAAPYPFLAEEIGYAVKYEYAVTAVDFLAR
RCRLAFLDCRAAYEALPKVVEVMGNELHWSASRKHKEFEDGVEYLKGMGLRL

GO term prediction

Biological Process

GO:0006072 glycerol-3-phosphate metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004368 glycerol-3-phosphate dehydrogenase activity
GO:0016491 oxidoreductase activity

Cellular Component

GO:0009331 glycerol-3-phosphate dehydrogenase complex