Protein

MCA_01332_1

Length
627 amino acids

Gene name: GUT2

Description: Glycerol-3-phosphate dehydrogenase, mitochondrial

Browser: contigA:4169222-4171106-

RNA-seq: read pairs 38423, FPKM 756.0, percentile rank 95.8% (100% = highest expression)

Protein function

Annotation:GUT2Glycerol-3-phosphate dehydrogenase, mitochondrial
KEGG:K00111glpA glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
EGGNOG:0PGEGGUT2Glycerol-3-phosphate dehydrogenase
SGD closest match:S000001417GUT2Glycerol-3-phosphate dehydrogenase, mitochondrial
CGD closest match:CAL0000181855GUT2Glycerol-3-phosphate dehydrogenase

Protein alignments

%idAln lengthE-value
MIA_04418_175.56%6300.0MIA_04418_1
A0A0J9XGN0_GEOCN69.27%6280.0Glycerol-3-phosphate dehydrogenase OS=Geotrichum candidum GN=BN980_GECA13s02507g PE=3 SV=1
UniRef50_A0A0J9XGN069.27%6280.0Glycerol-3-phosphate dehydrogenase n=9 Tax=Opisthokonta TaxID=33154 RepID=A0A0J9XGN0_GEOCN
Q6CEQ0_YARLI66.43%5720.0Glycerol-3-phosphate dehydrogenase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B13970g PE=3 SV=1
A0A060SZJ8_BLAAD64.01%5780.0Glycerol-3-phosphate dehydrogenase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C05346g PE=3 SV=1
A0A167DSI3_9ASCO60.89%6290.0Glycerol-3-phosphate dehydrogenase OS=Sugiyamaella lignohabitans GN=GUT2 PE=3 SV=1
A0A1E3PQP2_9ASCO58.79%6260.0Glycerol-3-phosphate dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48430 PE=3 SV=1
A0A1E4TKZ4_9ASCO52.46%5890.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30577 PE=4 SV=1
GPDM_YEAST46.80%6099e-178Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GUT2 PE=1 SV=2
A0A1D8PMP1_CANAL47.75%5992e-166Glycerol-3-phosphate dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GUT2 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7375
Predicted cleavage: 17

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 627

Detailed signature matches

  1. Family IPR000447
    FAD-dependent glycerol-3-phosphate dehydrogenase
    1. PR01001 (FADG3PDH)
    2. PS00978 (FAD_G3PDH_2)
    3. PS00977 (FAD_G3PDH_1)
  2. Domain IPR023753
    FAD/NAD(P)-binding domain
    1. SSF51905 (FAD/NAD(P...)
  3. Domain IPR006076
    FAD dependent oxidoreductase
    1. PF01266 (DAO)
  4. Domain IPR031656
    Alpha-glycerophosphate oxidase, C-terminal
    1. PF16901 (DAO_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.9.10
  2. G3DSA:3.40.50...
  3. NON_CYTOPLASM... (N...)
  4. SIGNAL_PEPTIDE (Sig...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SSF54373 (FAD-linke...)

Protein sequence

>MCA_01332_1
MFAARKRILSLAAVSSATVGLTAYSLINNKASANTQIDYELKHPHPQAPAPLPPSRKSHLERLKSATPDKPENVYDILVI
GGGATGTGIAVDAASRGLKVALVERDDFASGTSSRSTKLVHGGVRYLEKAVWNLDYNQYQLVKEALHERKVFLDIAPHLS
FALPIMIPVYKWWQLPYFWIGTKCYDLLAGKQNLQSSYLLTRSKALEAFPQLNPDTIKGAIVYYDGSHNDARMNVSLAVT
AAEMGATVLNHVEVVGLQKDAVTGSITGIVAKDLESSDNADHSIPVTAKTVINATGPFTDSIRKFDEFSVKEIVAPSSGV
HVILPGFYCPKNMGLLDAATSDGRVIFFLPWQGSTIAGTTDNPTNISANPIPSEEDIQFILNEVSKYFEGNLDVRREDVL
AAWSGIRPLVRDPKAKNTESLVRNHLITVSDSGLLTIAGGKWTTYRQMAKEAVDEAIKLGKLNPPIPETKTEELMLVGAE
KWDPLLYIHLAQKYNIDPQIAKHLSDNYGTRAYTIAETLAAERAKIMTPEYKKTHSLATSTVGSQLAAPYPFLAEEIDYA
VKYEYATTAVDFLARRTRLAFLDCKAAYQALPTVVDKMAKELNWNHSRRKKEYEDGVEFLKGMGLQL

GO term prediction

Biological Process

GO:0006072 glycerol-3-phosphate metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004368 glycerol-3-phosphate dehydrogenase activity
GO:0016491 oxidoreductase activity

Cellular Component

GO:0009331 glycerol-3-phosphate dehydrogenase complex