Protein
MIA_04403_1
Length
257 amino acids
Browser: contig05:1614009-1614815+
Protein function
| EGGNOG: | 0PPTW | DFR1 | dihydrofolate reductase |
|---|---|---|---|
| CGD closest match: | CAL0000177250 | DFR1 | Dihydrofolate reductase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_05491_1 | 34.167% | 120 | 3.78e-14 | MCA_05491_1 |
| A0A1E3PD95_9ASCO | 36.441% | 118 | 7.29e-13 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53532 PE=3 SV=1 |
| A0A060T4G3_BLAAD | 35.965% | 114 | 5.49e-13 | ARAD1A17072p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A17072g PE=3 SV=1 |
| UniRef50_A0A060T4G3 | 35.965% | 114 | 1.36e-09 | ARAD1A17072p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T4G3_BLAAD |
| A0A167FPM6_9ASCO | 34.211% | 114 | 1.34e-11 | Dihydrofolate reductase OS=Sugiyamaella lignohabitans GN=DFR1 PE=3 SV=1 |
| Q6CC38_YARLI | 71.429% | 35 | 1.59e-11 | YALI0C12771p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C12771g PE=3 SV=1 |
| A0A0J9XJB7_GEOCN | 32.231% | 121 | 1.45e-09 | Similar to Saccharomyces cerevisiae YOR236W DFR1 Dihydrofolate reductase OS=Geotrichum candidum GN=BN980_GECA18s02342g PE=3 SV=1 |
| Q5A5E0_CANAL | 52.941% | 34 | 1.35e-06 | Dihydrofolate reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DFR1 PE=3 SV=1 |
| A0A1E4TIE2_9ASCO | 58.621% | 29 | 4.70e-06 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_18002 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2500
Predicted cleavage: 69
Protein family membership
- Dihydrofolate reductase (IPR012259)
Domains and repeats
-
Domain
1
50
100
150
200
257
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MIA_04403_1 MSGTPPPTLTLILAASVPHLGIGLNGALPWRLSRELKYFKQRRARSPPAAEPQRARPAALPPSPAARPAALPEHDQNVVG SPPLHAPDAAAARAHQRRANARDPQRADAGARSARRRSSARSTGARAQQRAATHARRVFVIGGAQVYAAALRSPRASRIL LTEVVRDGDQPLADSGAIECDTFLGPEEGFTWYPHGEPGVEAPEGALWRRASVSELRRSLPADQVDLPEATDEYPELVEN GFRYRFTLWTKVEQKID
GO term prediction
Biological Process
GO:0006545 glycine biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0004146 dihydrofolate reductase activity
GO:0050661 NADP binding
Cellular Component
None predicted.