Protein

MIA_04395_1

Length
785 amino acids


Browser: contig05:1594228-1596586-

Protein function

EGGNOG:0PG4HSTE11kinase kinase kinase
SGD closest match:S000004354STE11Serine/threonine-protein kinase STE11
CGD closest match:CAL0000193264STE11Mitogen-activated protein kinase kinase kinase

Protein alignments

%idAln lengthE-value
A0A0J9X317_GEOCN41.395%6453.41e-138Similar to Saccharomyces cerevisiae YLR362W STE11 Signal transducing MEK kinase involved in pheromone response and pseudohyphal/invasive growth pathways, and the high osmolarity response pathway OS=Geotrichum candidum GN=BN980_GECA02s01352g PE=4 SV=1
UniRef50_A0A0J9X31741.395%6456.97e-135Similar to Saccharomyces cerevisiae YLR362W STE11 Signal transducing MEK kinase involved in pheromone response and pseudohyphal/invasive growth pathways, and the high osmolarity response pathway n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X317_GEOCN
MCA_04938_162.242%3391.81e-131MCA_04938_1
A0A167BWF7_9ASCO62.989%2814.94e-110Mitogen-activated protein kinase kinase kinase STE11 OS=Sugiyamaella lignohabitans GN=STE11 PE=4 SV=1
B5BLP7_BLAAD61.189%2866.74e-109Serine/threonine-protein kinase Aste11p OS=Blastobotrys adeninivorans GN=aste11 PE=4 SV=1
A0A1E3PRS4_9ASCO61.172%2732.40e-102Pkinase-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81184 PE=4 SV=1
F2Z643_YARLI57.840%2872.66e-95YALI0F13629p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13629g PE=4 SV=1
A0A1E4TLQ6_9ASCO56.727%2751.26e-92Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30775 PE=4 SV=1
STE11_YEAST47.869%3052.06e-83Serine/threonine-protein kinase STE11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STE11 PE=1 SV=3
A0A1D8PGY4_CANAL52.650%2834.49e-82Mitogen-activated protein kinase kinase kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=STE11 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0318

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 785

Detailed signature matches

    1. SSF47769 (SAM/Point...)
    1. PF00536 (SAM_1)
    2. PS50105 (SAM_DOMAIN)
    3. SM00454 (SAM_4)
    1. SM01304 (Ras_bdg_2_2)
    2. PF14847 (Ras_bdg_2)
    1. SSF56112 (Protein k...)
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
    1. PS00107 (PROTEIN_KI...)
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd09534 (SAM_Ste11_...)
  2. mobidb-lite (disord...)

Residue annotation

  1. putative heterodim...
  2. heterodimer interf...
  3. homodimer interfac...

Protein sequence

>MIA_04395_1
MDSFLPPPEPLSPLRSSFDMDDEPERPTGLSTPSSSPPGSSGNNTTAPHNNPASTPVSAWTRHHVRDWLEDLGCGAYVRL
FDENHIAGDILLEVDEAALQEIGVARVGDRIRLGLSLEAMRRAYAQAEVAALQQQRDLAAQQYAQQNAQHAQQIAQMAQL
RLRHGSYAGSTLTPGGHQAAAPSPVESFFTPSTGESLLGGLKTEKQPPATFINYKGQCLQVNVSKYFDAGPVKKRVIKKF
QQKGMALWEGEEKVRSDSVVMYVTDEQGSPRAIEGIELISYCQTQEYKERDRILVCVRGHSPTAIQLATARQIVRQQHKQ
QQMKQKQQIHPRSKLDGFRPKSQDISRNLQSLQEFFPEAGTQALRKTIRNSQMYTKRMSRLSRVSNRSSIAMYLHDSDGE
EASPPVPVLEDYLPTGGSAEARAIAGTAGAIGVSASPSPSAVTSPFSLVLPTGKERPVSFMSTASASSSSSSSSVEEKTL
PPVPATLVMMDTADIPESEEEFAKLFQREQSGPSKWIRGKEIGAGSFGKVYLGLNSITGELMAVKQVELPSSAKEQDQRR
RALMVEALQREMSLLRDLEHPNIVQYLGSNCENNVLNVFLEYVPGGSVASKMRSRESGVFEEQEVRRVVRQILEGLKYLH
SRSIIHRDIKGANVLMDDDGLVKISDFGISKKLEEEKTNARTSIQGSPFWMAPEVARQKPYTFKTDIWSLGCLIVEMFTG
SHPFPHFMSLQALYNMAKETPILPAIPQGISASAQDFLAQAFEIDYNKRPTAAEMLEHPFVKGNF

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding

Cellular Component

None predicted.