Protein
MIA_04353_1
Length
240 amino acids
Browser: contig05:1489304-1490157+
Protein function
EGGNOG: | 0PNXJ | TIM21 | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix |
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SGD closest match: | S000003265 | TIM21 | Mitochondrial import inner membrane translocase subunit TIM21 |
CGD closest match: | CAL0000180033 | TIM21 | Mitochondrial import inner membrane translocase subunit TIM21 |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_04615_1 | 66.279% | 172 | 1.49e-79 | MCA_04615_1 |
A0A0J9X4R4_GEOCN | 56.742% | 178 | 5.02e-67 | Similar to Saccharomyces cerevisiae YGR033C TIM21 Nonessential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex) OS=Geotrichum candidum GN=BN980_GECA02s06940g PE=4 SV=1 |
UniRef50_A0A0J9X4R4 | 56.742% | 178 | 1.03e-63 | Similar to Saccharomyces cerevisiae YGR033C TIM21 Nonessential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X4R4_GEOCN |
A0A060T7W4_BLAAD | 50.867% | 173 | 2.76e-51 | ARAD1C31262p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C31262g PE=4 SV=1 |
A0A167DBI7_9ASCO | 51.744% | 172 | 1.23e-48 | Tim21p OS=Sugiyamaella lignohabitans GN=TIM21 PE=4 SV=1 |
A0A1E3PFM4_9ASCO | 41.758% | 182 | 6.07e-40 | TIM21-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84351 PE=4 SV=1 |
A0A1E4TH17_9ASCO | 41.481% | 135 | 3.56e-33 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31812 PE=4 SV=1 |
TIM21_YARLI | 38.194% | 144 | 8.06e-30 | Mitochondrial import inner membrane translocase subunit TIM21 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=TIM21 PE=3 SV=1 |
TIM21_CANAL | 36.517% | 178 | 5.05e-26 | Mitochondrial import inner membrane translocase subunit TIM21 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TIM21 PE=3 SV=1 |
TIM21_YEAST | 34.857% | 175 | 3.72e-24 | Mitochondrial import inner membrane translocase subunit TIM21 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TIM21 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9995
Predicted cleavage: 79
Protein family membership
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
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mobidb-lite (disord...)
Protein sequence
>MIA_04353_1 MPATILNTCLLRSSRLLATPCVHRQIGYRSITSTTGYLRPLLAYPRPTTRSFTASTSRRSSSKSSSRGSGIVNGISRAVS FSFYACLIVGGIGTLGIVGYLFVSEILLPSSDVALYNKTFSIIEKDPVCLEVLGDRIKAHGEEQSNKWARSRPIAANRGF DKYQREHMWMQFHVQGEKNSGLVRLEMVRDPHGSNTFEYRYLVLEVPGFERIYLIDKTPQPARKTASGLFWGIKWGKKQD
GO term prediction
Biological Process
GO:0030150 protein import into mitochondrial matrix
Molecular Function
None predicted.
Cellular Component
GO:0005744 mitochondrial inner membrane presequence translocase complex