Protein

MIA_04336_1

Length
350 amino acids

Browser: contig05:1442761-1443845-

Protein function

EGGNOG:0PGBAPHO85Negative regulator of the PHO system
SGD closest match:S000005952PHO85Cyclin-dependent protein kinase PHO85
CGD closest match:CAL0000200290PHO85Cyclin-dependent serine/threonine-protein kinase

Protein alignments

%idAln lengthE-value
A0A0J9XGK4_GEOCN85.172%2900.0Similar to Saccharomyces cerevisiae YGR040W KSS1 Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response OS=Geotrichum candidum GN=BN980_GECA16s01341g PE=3 SV=1
MCA_03106_178.549%3170.0MCA_03106_1
A0A1E3PJF6_9ASCO80.743%2966.99e-177Negative regulator of the PHO system OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_42361 PE=3 SV=1
PHO85_YARLI80.137%2924.06e-174Negative regulator of the PHO system OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PHO85 PE=3 SV=1
UniRef50_K0L0C678.246%2856.24e-164Negative regulator of the PHO system n=14 Tax=Opisthokonta TaxID=33154 RepID=K0L0C6_WICCF
A0A1E4TCM4_9ASCO74.570%2917.16e-162Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_140099 PE=3 SV=1
A0A1D8PDA6_CANAL74.411%2973.68e-161Cyclin-dependent serine/threonine-protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PHO85 PE=3 SV=1
PHO85_YEAST66.779%2983.31e-143Cyclin-dependent protein kinase PHO85 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PHO85 PE=1 SV=2
A0A167FJB1_9ASCO79.747%2376.00e-141Cyclin-dependent serine/threonine-protein kinase PHO85 OS=Sugiyamaella lignohabitans GN=PHO85 PE=4 SV=1
A0A060T399_BLAAD72.400%2508.46e-137ARAD1C30976p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C30976g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0855

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 350

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. NON_CYTOPLASM... (N...)
  4. PIRSF000654 (ILK)
  5. SIGNAL_PEPTIDE (Sig...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SIGNAL_PEPTID... (S...)
  9. SignalP-noTM
  10. TMhelix

Protein sequence

>MIA_04336_1
MSTLSQYVYAVSLACFLFISMTSTNSILGSNNLPAHATSDSYRLEKLGEGTYATVYKGRNRATGQLVALKEITLDSEEGT
PSTAIREISLMKELRHANILRLYDVIHTDNKLNLVFEYMDRDLKKYMDTYGVKGALDPKIIKSFMFQLLKGVYFCHENRV
LHRDLKPQNLLINSRAQLKLADFGLARAFGIPVNTFSNEVVTLWYRAPDVLLGSRTYSTSIDIWSAGCILAEMFTGRPLF
AGNSNEDQLQRIFKIMGTPNEHTWPNISALPNYSASYPQYPPQDLRSIIPQIDPVGLDLLQHLLQLMPERRISAQQALQH
PWFAEYNAVPTTAAGSAVAEYNQQQQPAQY

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.