Protein

MCA_03106_1

Length
320 amino acids


Gene name: PHO85

Description: Cyclin-dependent kinase; in S. cerevusiae involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle

Browser: contigB:3388785-3389888+

RNA-seq: read pairs 2399, FPKM 92.3, percentile rank 77.3% (100% = highest expression)

Protein function

Annotation:PHO85Cyclin-dependent kinase; in S. cerevusiae involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle
EGGNOG:0PGBAPHO85Negative regulator of the PHO system
SGD closest match:S000005952PHO85Cyclin-dependent protein kinase PHO85
CGD closest match:CAL0000200290PHO85Cyclin-dependent serine/threonine-protein kinase

Protein alignments

%idAln lengthE-value
PHO85_YARLI84.69%2940.0Negative regulator of the PHO system OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PHO85 PE=3 SV=1
A0A0J9XGK4_GEOCN83.06%3010.0Similar to Saccharomyces cerevisiae YGR040W KSS1 Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response OS=Geotrichum candidum GN=BN980_GECA16s01341g PE=3 SV=1
MIA_04336_178.55%3172e-177MIA_04336_1
A0A1E3PJF6_9ASCO82.59%2931e-175Negative regulator of the PHO system OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_42361 PE=3 SV=1
UniRef50_K0L0C677.89%2942e-163Negative regulator of the PHO system n=14 Tax=Opisthokonta TaxID=33154 RepID=K0L0C6_WICCF
A0A1E4TCM4_9ASCO75.17%2941e-165Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_140099 PE=3 SV=1
A0A1D8PDA6_CANAL77.85%2897e-163Cyclin-dependent serine/threonine-protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PHO85 PE=3 SV=1
PHO85_YEAST70.76%3011e-147Cyclin-dependent protein kinase PHO85 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PHO85 PE=1 SV=2
A0A167FJB1_9ASCO81.22%2457e-144Cyclin-dependent serine/threonine-protein kinase PHO85 OS=Sugiyamaella lignohabitans GN=PHO85 PE=4 SV=1
A0A060T399_BLAAD80.43%2356e-137ARAD1C30976p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C30976g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0892

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 320

Detailed signature matches

    1. SSF56112 (Protein k...)
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
    1. PS00107 (PROTEIN_KI...)
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures

Protein sequence

>MCA_03106_1
MSTSSQFQQLEKLGEGTYATVYKGKNKSTGQLVALKEINLDSEEGTPSTAIREISLMKELKHPNIVRLYDVIHTENKLNL
VFEYMDKDLKKYMDTTGKRGALDAPTVKHFMYQLLKGILFCHDNRVLHRDLKPQNLLINSRGHLKLADFGLARAFGIPVN
TFSNEVVTLWYRAPDVLLGSRTYSTSIDIWSAGCILAEMFTGRPLFAGNSNDDQLQKIFKIMGTPNEATWPGISQLPNYN
PSFPQYAPQDLRVIIPQIDSQALDLLQALLRMKPESRISAGEALQHPWFAEYNQQQVQYPMANNMGVQGEYQQQVMQPQY

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.