Protein

MIA_04312_1

Length
523 amino acids

Browser: contig05:1394559-1396131-

Protein function

EGGNOG:0PFUITRM1N2,n2-dimethylguanosine tRNA methyltransferase
SGD closest match:S000002527TRM1tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial
CGD closest match:CAL0000179806TRM1tRNA (guanine(26)-N(2))-dimethyltransferase

Protein alignments

%idAln lengthE-value
MCA_01886_165.402%4480.0MCA_01886_1
A0A0J9X6B4_GEOCN54.219%5570.0tRNA (guanine(26)-N(2))-dimethyltransferase OS=Geotrichum candidum GN=BN980_GECA03s05389g PE=3 SV=1
A0A167C701_9ASCO50.735%5440.0tRNA (guanine(26)-N(2))-dimethyltransferase OS=Sugiyamaella lignohabitans GN=TRM1 PE=3 SV=1
UniRef50_A0A167C70150.735%5440.0tRNA (guanine(26)-N(2))-dimethyltransferase n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A167C701_9ASCO
A0A060T461_BLAAD51.969%5080.0tRNA (guanine(26)-N(2))-dimethyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C41756g PE=3 SV=1
A0A1E3PLC4_9ASCO48.289%5263.03e-166tRNA (guanine(26)-N(2))-dimethyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_32585 PE=3 SV=1
Q6C410_YARLI48.805%5021.74e-152tRNA (guanine(26)-N(2))-dimethyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E30723g PE=3 SV=1
TRM1_YEAST44.841%5332.69e-145tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRM1 PE=1 SV=1
Q5A863_CANAL41.941%5462.84e-132tRNA (guanine(26)-N(2))-dimethyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TRM1 PE=3 SV=1
A0A1E4THU9_9ASCO42.802%5145.93e-127tRNA (guanine(26)-N(2))-dimethyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_24269 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0518

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 523

Detailed signature matches

  1. Family IPR002905
    tRNA methyltransferase, Trm1
    1. PF02005 (TRM)
    2. TIGR00308
    3. PS51626 (SAM_MT_TRM1)
  2. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd02440 (AdoMet_MTases)
  3. mobidb-lite (disord...)

Residue annotation

  1. S-adenosylmethioni...

Protein sequence

>MIA_04312_1
MAKGLVSSPPAASGTAAAPIPEGMAVVAEGSASILMPKDKVFYNPVQQFNRDLSIVGIRAWSNLHLKARKRSATPKPAEP
DRQPKKARVDDEQDPARYLEILEALSASGLRAIRYAAEIPTAKSVLANDFSAAAVESIRSNAQFSNVAERVAPVHGDANV
LMYSRKTSPVHVVDLDPYGSATPFLDAAVQALVSDGLLLVTCTDLAVLAGNGYPEKCFALYGGQTLYSDARHESALRLVL
ATIANTAARYGLAIEPQLSLSIDFYVRLFVKVKRSPQTVKLNASKTISVAHCRGCGATFSQPLGKATPAAHGSGFKFGYA
RITAPGSECPHCRSSLVVAGPMWGAPIHNPAFIDEMLAVHGSISGDAAQAPLYGTLPRIQGMLSAARNELPEIPFYVNVQ
SLASTLRASSPPHKVFLSALCNAGYRVSYTHAQAGAIKTDAPHSVLLDIMKAWVIKDQEGKVSKNLKPGSPGYAIMQDPQ
PSQAINFEMHPRALELEEFRKSKLVRYQVNPTKNWGPKAKASG

GO term prediction

Biological Process

GO:0008033 tRNA processing

Molecular Function

GO:0003723 RNA binding
GO:0004809 tRNA (guanine-N2-)-methyltransferase activity

Cellular Component

None predicted.