Protein

MCA_01886_1

Length
605 amino acids

Gene name: TRM1

Description: tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial

Browser: contigA:5775141-5777039+

RNA-seq: read pairs 781, FPKM 15.9, percentile rank 35.4% (100% = highest expression)

Protein function

Annotation:TRM1tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial
KEGG:K00555TRMT1 tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
EGGNOG:0PFUITRM1N2,n2-dimethylguanosine tRNA methyltransferase
SGD closest match:S000002527TRM1tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial
CGD closest match:CAL0000179806TRM1tRNA (guanine(26)-N(2))-dimethyltransferase

Protein alignments

%idAln lengthE-value
A0A0J9X6B4_GEOCN57.79%5780.0tRNA (guanine(26)-N(2))-dimethyltransferase OS=Geotrichum candidum GN=BN980_GECA03s05389g PE=3 SV=1
MIA_04312_165.40%4480.0MIA_04312_1
A0A167C701_9ASCO53.83%5740.0tRNA (guanine(26)-N(2))-dimethyltransferase OS=Sugiyamaella lignohabitans GN=TRM1 PE=3 SV=1
UniRef50_A0A167C70153.83%5740.0tRNA (guanine(26)-N(2))-dimethyltransferase n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A167C701_9ASCO
A0A060T461_BLAAD54.73%4444e-169tRNA (guanine(26)-N(2))-dimethyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C41756g PE=3 SV=1
A0A1E3PLC4_9ASCO49.21%4452e-147tRNA (guanine(26)-N(2))-dimethyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_32585 PE=3 SV=1
Q6C410_YARLI51.04%4335e-137tRNA (guanine(26)-N(2))-dimethyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E30723g PE=3 SV=1
TRM1_YEAST45.45%4511e-128tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRM1 PE=1 SV=1
Q5A863_CANAL43.76%4732e-122tRNA (guanine(26)-N(2))-dimethyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TRM1 PE=3 SV=1
A0A1E4THU9_9ASCO43.22%4722e-121tRNA (guanine(26)-N(2))-dimethyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_24269 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0606

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 605

Detailed signature matches

  1. Family IPR002905
    tRNA methyltransferase, Trm1
    1. PF02005 (TRM)
    2. TIGR00308
    3. PS51626 (SAM_MT_TRM1)
  2. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd02440 (AdoMet_MTases)
  3. mobidb-lite (disord...)

Residue annotation

  1. S-adenosylmethioni...

Protein sequence

>MCA_01886_1
MTTIASNSNDSVKLEETSSSAPETTTANLPTGASKTYDENMEMTVVTEGSASILFPKGNEVFYNPVQQFNRDISTVAIRA
WSNIYSQRMKELKNKKKLNKGKNKREASSPRASDSKKICLEDGESTEKTESATTEKTEKLTHTEESKSEESKEQTSATDT
TKPTEEQSPKRFVEIIEALSASGLRAIRYASEIPTAKVVYANDFSESAVKSIKHNAEYSKVSSLIVPNQGDANMFMYTHK
PAKENVHVVDLDPYGSATPFIDAALQCVKDDGLLLVTCTDLSVLAGNGYPEKCFAQYGGQTLYSDACHESALRLVLGMIS
NTAARYGMAIEPLLSLSIDFYVRLFIRVKKSPATVKFNASKTMIVYQCTGCGATANQPLGKAVMKNNQPKFGYAQLPQQD
SIIDGPSASNTGKNTCVHCHSPIVVAGPMWGAHLHDHSFIDEMLSIHKTLDPSIYGTLPRIQGMLTLAKEELLDVPFFVN
VQSVASKLKASSPPHRQMISAICNLGYRASYTHAQPGAIKTDAPYGVLLDIMKAWIKQEQNGVVSKNLKQGSAGYRVLQD
LEPKVKVSFEDHPRALELETFRKSKLLRFQINPTKNWGPKPKASG

GO term prediction

Biological Process

GO:0008033 tRNA processing

Molecular Function

GO:0003723 RNA binding
GO:0004809 tRNA (guanine-N2-)-methyltransferase activity

Cellular Component

None predicted.