Protein

MIA_04284_1

Length
1,041 amino acids

Browser: contig05:1303670-1307008+

Protein function

EGGNOG:0PHGZRGA2Rho-type gtpase-activating protein
SGD closest match:S000005653RGA1Rho-type GTPase-activating protein 1
CGD closest match:CAL0000179204RGA2Rga2p

Protein alignments

%idAln lengthE-value
MCA_05670_144.561%5709.23e-133MCA_05670_1
A0A0J9YHE0_GEOCN37.936%6591.26e-122Similar to Saccharomyces cerevisiae YOR127W RGA1 GTPase-activating protein for the polarity-establishment protein Cdc42p OS=Geotrichum candidum GN=BN980_GECA01s02991g PE=4 SV=1
UniRef50_A0A0J9YHE037.936%6592.58e-119Similar to Saccharomyces cerevisiae YOR127W RGA1 GTPase-activating protein for the polarity-establishment protein Cdc42p n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9YHE0_GEOCN
A0A060T1E4_BLAAD33.696%5525.29e-73ARAD1C15928p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C15928g PE=4 SV=1
A0A1E3PDK3_9ASCO33.453%5591.70e-71Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84163 PE=4 SV=1
A0A167D146_9ASCO59.296%1992.51e-68Rga1p OS=Sugiyamaella lignohabitans GN=RGA1 PE=4 SV=1
Q6CF51_YARLI38.757%3381.57e-59YALI0B10241p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B10241g PE=4 SV=1
A0A1E4TFU9_9ASCO38.384%2978.53e-49Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31537 PE=4 SV=1
Q5AMQ3_CANAL44.660%2067.99e-48Rga2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RGA2 PE=4 SV=1
RGA1_YEAST26.521%4111.84e-29Rho-type GTPase-activating protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RGA1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0445

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 1041

Detailed signature matches

  1. Domain IPR001781
    Zinc finger, LIM-type
    1. PF00412 (LIM)
    2. PS50023 (LIM_DOMAIN_2)
    3. PS00478 (LIM_DOMAIN_1)
    4. SM00132 (lim_4)
  2. Domain IPR008936
    Rho GTPase activation protein
    1. SSF48350 (GTPase ac...)
  3. Domain IPR000198
    Rho GTPase-activating protein domain
    1. SM00324 (RhoGAP_3)
    2. PF00620 (RhoGAP)
    3. PS50238 (RHOGAP)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.28...
  3. G3DSA:1.10.55...
  4. G3DSA:2.10.11...
  5. cd00159 (RhoGAP)
  6. cd09395 (LIM2_Rga)
  7. mobidb-lite (disord...)

Residue annotation

  1. Zn binding site cd...
  2. catalytic residue ...
  3. GTPase interaction...

Protein sequence

>MIA_04284_1
MSTDSADHTGDATAVDPASAAPNTDTNPKYPCKKCSQLIEEGQIYQLGPHRWHVECFRCSICNSLLRHDFNIHLLGNGSL
FCANCSYTCSVCNKIIDGMAVLTDDLAFCSSCFRCRNCKKKIDDTQYARTSQGTFCMKCHQALLARKKRAAALKATTSST
NTATDTTTANNNNATSNSNTPTKTSPTNSNIPTFQPLPPPPFASSGNHPPAFSLSGHASSPSLGQYSTMANHAPSPFKEK
SLPQLPTHEPPQDGQISPSSAPSSLNRTNSYNQALALSQGISPPPRPPPPLERIPPRVPLKTQPMSAKPALDPPLVSTSH
SSPTVSSTSFVFNNQESPLPALGSKFMPKRELPSPQEDSSSRKLASPELDFKSTPSRGGIYIDSALSSPNDFSDADLALR
LPKIEGVKLDLDNSSSSSSENLEKYMMERSALQAMSPNYNNIPQTPEDEIMNRLEPRAPSGHYRSASENRLSVVSPLTRD
LMDARKRIAELELQLRNSKNNNASLDSNINEKRKTVAGLEAKGEVAKMELGMLDEALAQKNNLQDVYPELIKRFVDEVSH
YKESLRAEIEELMLTRNRLEQKNAELAKMHEVWIEKNMGIEAENKQLLMLNSRLTRSVEEKVGPILDQHDAADDKKSGGR
RFWKRPTAAVAKGVKGFNKVFNQDQSQQLHAPLISTGPYSDLDGSITMISNNTVNSSESGEERSKRWFKTSTDAPLMAPT
VSTSSATSLMGMPIEKRIEYENTNIPQIVTRCVQEVEARGMEFEGIYRKSGARSQVSSIEEAFERAGGENVDDSVLDGDI
SGVTSALKQYLRYLPNPLVPFDVYEEFVEISREISKSPDYATDMLRALINGLPQPYKECLSYVVQHLVKVSQHADINLMT
TRNLAVVFAPTLVRHTTGEREIVDMQARNDGTQLLIDRYSTIFGDVFIRTDPPPIPTQASLNTSSSATNGIKIVTDINTD
KLDIDTEATMAAVAATNSNGVGDVSRDVETGSERSSVPTVSGSVHGAYEDMIVTHNDSALETTPVIPPVHYPMTLTSANV
I

GO term prediction

Biological Process

GO:0007165 signal transduction

Molecular Function

None predicted.

Cellular Component

None predicted.