MIA_04264_1

Protein

Length

1,813 amino acids

Protein function

EGGNOG:	0PFP0	FG05990.1	Histidine kinase
SGD closest match:	S000001409	SLN1	Osmosensing histidine protein kinase SLN1
CGD closest match:	CAL0000187540	NIK1	Histidine protein kinase NIK1

Protein alignments

	%id	Aln length	E-value
A0A0J9X3J1_GEOCN	53.77%	928	0.0	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA01s09998g PE=4 SV=1
UniRef50_A0A0J9X3J1	53.77%	928	0.0	Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X3J1_GEOCN
A0A060T425_BLAAD	47.99%	921	0.0	ARAD1C01232p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C01232g PE=4 SV=1
A0A1E3PSB7_9ASCO	55.46%	467	7e-159	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48401 PE=4 SV=1
Q6C775_YARLI	40.19%	214	3e-34	YALI0E03168p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E03168g PE=4 SV=1
NIK1_CANAL	42.19%	192	2e-33	Histidine protein kinase NIK1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NIK1 PE=1 SV=3
MCA_02755_1	38.21%	212	4e-33	MCA_02755_1
A0A167E0V0_9ASCO	39.25%	214	3e-33	Sln1p OS=Sugiyamaella lignohabitans GN=SLN1 PE=4 SV=1
A0A1E4TFT3_9ASCO	38.42%	203	9e-33	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31477 PE=4 SV=1
SLN1_YEAST	34.07%	135	1e-11	Osmosensing histidine protein kinase SLN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLN1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0050

Protein family membership

None predicted.

Domains and repeats

Domain
893 - 1,012
PAS domain (IPR000014)
PAS fold-3 (IPR013655)
1,027 - 1,155
PAS domain (IPR000014)
1,161 - 1,241
Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (IPR003661)
1,245 - 1,470
Histidine kinase-like ATPase, C-terminal domain (IPR003594)
1,682 - 1,812
CheY-like superfamily (IPR011006)
Signal transduction response regulator, receiver domain (IPR001789)
Domain
1,181 - 1,462
Histidine kinase domain (IPR005467)
Domain
1,331 - 1,345
Signal transduction histidine kinase-related protein, C-terminal (IPR004358)
1,422 - 1,440
Signal transduction histidine kinase-related protein, C-terminal (IPR004358)
1,446 - 1,459
Signal transduction histidine kinase-related protein, C-terminal (IPR004358)
Repeat
967 - 1,009
PAC motif (IPR001610)
1,112 - 1,154
PAC motif (IPR001610)

1 200 400 600 800 1000 1200 1400 1600 1813

Detailed signature matches

IPR000014

PAS domain
1. SSF55785 (PYP-like ...)
  
  1,032 - 1,155
  
  SUPERFAMILY
  SSF55785 (PYP-like sensor domain (PAS domain))
  
  900 - 1,012
  
  SUPERFAMILY
  SSF55785 (PYP-like sensor domain (PAS domain))
2. PS50112 (PAS)
  
  893 - 963
  
  PROSITE profiles
  PS50112 (PAS)
3. cd00130 (PAS)
  
  1,049 - 1,151
  
  CDD
  cd00130 (PAS)
  
  916 - 1,006
  
  CDD
  cd00130 (PAS)
4. SM00091 (pas_2)
  
  1,027 - 1,093
  
  SMART
  SM00091 (pas_2)
  
  895 - 961
  
  SMART
  SM00091 (pas_2)
IPR013655

PAS fold-3
1. PF08447 (PAS_3)
  
  920 - 1,002
  
  Pfam
  PF08447 (PAS_3)
IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain
1. cd00082 (HisKA)
  
  1,172 - 1,235
  
  CDD
  cd00082 (HisKA)
2. SSF47384 (Homodimer...)
  
  1,161 - 1,241
  
  SUPERFAMILY
  SSF47384 (Homodimeric domain of signal transducing histidine kinase)
3. SM00388 (HisKA_10)
  
  1,174 - 1,239
  
  SMART
  SM00388 (HisKA_10)
4. PF00512 (HisKA)
  
  1,174 - 1,239
  
  Pfam
  PF00512 (HisKA)
IPR005467

Histidine kinase domain
1. PS50109 (HIS_KIN)
  
  1,181 - 1,462
  
  PROSITE profiles
  PS50109 (HIS_KIN)
IPR003594

Histidine kinase-like ATPase, C-terminal domain
1. G3DSA:3.30.56...
  
  1,245 - 1,470
  
  GENE3D
  G3DSA:3.30.565.10 (G3DSA:3.30.565.10)
2. PF02518 (HATPase_c)
  
  1,286 - 1,364
  
  Pfam
  PF02518 (HATPase_c)
3. SSF55874 (ATPase do...)
  
  1,277 - 1,361
  
  SUPERFAMILY
  SSF55874 (ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase)
  
  1,418 - 1,468
  
  SUPERFAMILY
  SSF55874 (ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase)
4. SM00387 (HKATPase_4)
  
  1,286 - 1,462
  
  SMART
  SM00387 (HKATPase_4)
IPR004358

Signal transduction histidine kinase-related protein, C-terminal
1. PR00344 (BCTRLSENSOR)
  
  1,422 - 1,440
  
  PRINTS
  PR00344 (BCTRLSENSOR)
  
  1,331 - 1,345
  
  PRINTS
  PR00344 (BCTRLSENSOR)
  
  1,446 - 1,459
  
  PRINTS
  PR00344 (BCTRLSENSOR)
IPR011006

CheY-like superfamily
1. SSF52172 (CheY-like)
  
  1,682 - 1,812
  
  SUPERFAMILY
  SSF52172 (CheY-like)
IPR001789

Signal transduction response regulator, receiver domain
1. PS50110 (RESPONSE_R...)
  
  1,684 - 1,812
  
  PROSITE profiles
  PS50110 (RESPONSE_REGULATORY)
2. PF00072 (Response_reg)
  
  1,685 - 1,807
  
  Pfam
  PF00072 (Response_reg)
3. cd00156 (REC)
  
  1,686 - 1,812
  
  CDD
  cd00156 (REC)
4. SM00448 (REC_2)
  
  1,683 - 1,808
  
  SMART
  SM00448 (REC_2)
IPR001610

PAC motif
1. SM00086 (pac_2)
  
  1,112 - 1,154
  
  SMART
  SM00086 (pac_2)
  
  967 - 1,009
  
  SMART
  SM00086 (pac_2)

no IPR

Unintegrated signatures

Coil

1,151 - 1,171

COILS
Coil (Coil)
G3DSA:1.10.28...

1,173 - 1,235

GENE3D
G3DSA:1.10.287.130 (G3DSA:1.10.287.130)
G3DSA:3.30.45...

1,026 - 1,172

GENE3D
G3DSA:3.30.450.20 (G3DSA:3.30.450.20)

894 - 1,025

GENE3D
G3DSA:3.30.450.20 (G3DSA:3.30.450.20)
G3DSA:3.40.50...

1,669 - 1,813

GENE3D
G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
cd00075 (HATPase_c)

1,291 - 1,457

CDD
cd00075 (HATPase_c)
mobidb-lite (disord...)

437 - 508

MobiDB Lite
mobidb-lite (disorder_prediction)

211 - 233

MobiDB Lite
mobidb-lite (disorder_prediction)

1,659 - 1,681

MobiDB Lite
mobidb-lite (disorder_prediction)

367 - 424

MobiDB Lite
mobidb-lite (disorder_prediction)

776 - 832

MobiDB Lite
mobidb-lite (disorder_prediction)

853 - 885

MobiDB Lite
mobidb-lite (disorder_prediction)

281 - 310

MobiDB Lite
mobidb-lite (disorder_prediction)

1,374 - 1,403

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative active si...

921V

putative active site
921V, 925V, 931Q, 944I, 945H, 946P, 972L, 977G
CDD
cd00130 (PAS)

925V

putative active site
921V, 925V, 931Q, 944I, 945H, 946P, 972L, 977G
CDD
cd00130 (PAS)

931Q

putative active site
921V, 925V, 931Q, 944I, 945H, 946P, 972L, 977G
CDD
cd00130 (PAS)

944I

putative active site
921V, 925V, 931Q, 944I, 945H, 946P, 972L, 977G
CDD
cd00130 (PAS)

945H

putative active site
921V, 925V, 931Q, 944I, 945H, 946P, 972L, 977G
CDD
cd00130 (PAS)

946P

putative active site
921V, 925V, 931Q, 944I, 945H, 946P, 972L, 977G
CDD
cd00130 (PAS)

972L

putative active site
921V, 925V, 931Q, 944I, 945H, 946P, 972L, 977G
CDD
cd00130 (PAS)

977G

putative active site
921V, 925V, 931Q, 944I, 945H, 946P, 972L, 977G
CDD
cd00130 (PAS)
heme pocket cd00130

941Y

heme pocket
941Y, 944I, 952F, 955L, 956L, 984Y, 986C
CDD
cd00130 (PAS)

944I

heme pocket
941Y, 944I, 952F, 955L, 956L, 984Y, 986C
CDD
cd00130 (PAS)

952F

heme pocket
941Y, 944I, 952F, 955L, 956L, 984Y, 986C
CDD
cd00130 (PAS)

955L

heme pocket
941Y, 944I, 952F, 955L, 956L, 984Y, 986C
CDD
cd00130 (PAS)

956L

heme pocket
941Y, 944I, 952F, 955L, 956L, 984Y, 986C
CDD
cd00130 (PAS)

984Y

heme pocket
941Y, 944I, 952F, 955L, 956L, 984Y, 986C
CDD
cd00130 (PAS)

986C

heme pocket
941Y, 944I, 952F, 955L, 956L, 984Y, 986C
CDD
cd00130 (PAS)
putative active si...

1,052S

putative active site
1,052S, 1,056W, 1,062C, 1,075R, 1,076I, 1,077H, 1,078P, 1,117L, 1,122N
CDD
cd00130 (PAS)

1,056W

putative active site
1,052S, 1,056W, 1,062C, 1,075R, 1,076I, 1,077H, 1,078P, 1,117L, 1,122N
CDD
cd00130 (PAS)

1,062C

putative active site
1,052S, 1,056W, 1,062C, 1,075R, 1,076I, 1,077H, 1,078P, 1,117L, 1,122N
CDD
cd00130 (PAS)

1,075R

putative active site
1,052S, 1,056W, 1,062C, 1,075R, 1,076I, 1,077H, 1,078P, 1,117L, 1,122N
CDD
cd00130 (PAS)

1,076I

putative active site
1,052S, 1,056W, 1,062C, 1,075R, 1,076I, 1,077H, 1,078P, 1,117L, 1,122N
CDD
cd00130 (PAS)

1,077H

putative active site
1,052S, 1,056W, 1,062C, 1,075R, 1,076I, 1,077H, 1,078P, 1,117L, 1,122N
CDD
cd00130 (PAS)

1,078P

putative active site
1,052S, 1,056W, 1,062C, 1,075R, 1,076I, 1,077H, 1,078P, 1,117L, 1,122N
CDD
cd00130 (PAS)

1,117L

putative active site
1,052S, 1,056W, 1,062C, 1,075R, 1,076I, 1,077H, 1,078P, 1,117L, 1,122N
CDD
cd00130 (PAS)

1,122N

putative active site
1,052S, 1,056W, 1,062C, 1,075R, 1,076I, 1,077H, 1,078P, 1,117L, 1,122N
CDD
cd00130 (PAS)
heme pocket cd00130

1,072Y

heme pocket
1,072Y, 1,076I, 1,084C, 1,090M, 1,091L, 1,129I, 1,131Y
CDD
cd00130 (PAS)

1,076I

heme pocket
1,072Y, 1,076I, 1,084C, 1,090M, 1,091L, 1,129I, 1,131Y
CDD
cd00130 (PAS)

1,084C

heme pocket
1,072Y, 1,076I, 1,084C, 1,090M, 1,091L, 1,129I, 1,131Y
CDD
cd00130 (PAS)

1,090M

heme pocket
1,072Y, 1,076I, 1,084C, 1,090M, 1,091L, 1,129I, 1,131Y
CDD
cd00130 (PAS)

1,091L

heme pocket
1,072Y, 1,076I, 1,084C, 1,090M, 1,091L, 1,129I, 1,131Y
CDD
cd00130 (PAS)

1,129I

heme pocket
1,072Y, 1,076I, 1,084C, 1,090M, 1,091L, 1,129I, 1,131Y
CDD
cd00130 (PAS)

1,131Y

heme pocket
1,072Y, 1,076I, 1,084C, 1,090M, 1,091L, 1,129I, 1,131Y
CDD
cd00130 (PAS)
dimer interface cd...

1,178F

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)

1,182M

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)

1,186I

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)

1,189P

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)

1,193I

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)

1,196M

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)

1,212Y

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)

1,216I

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)

1,219S

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)

1,223L

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)

1,226V

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)

1,230I

dimer interface
1,178F, 1,182M, 1,186I, 1,189P, 1,193I, 1,196M, 1,212Y, 1,216I, 1,219S, 1,223L, 1,226V, 1,230I
CDD
cd00082 (HisKA)
phosphorylation si...

1,184H

phosphorylation site
1,184H
CDD
cd00082 (HisKA)
ATP binding site c...

1,297N

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,301N

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,304K

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,335V

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,337D

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,339G

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,341G

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,342F

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,425G

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,426L

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,427G

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,428L

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,444C

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,446S

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,451G

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,452S

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)

1,454F

ATP binding site
1,297N, 1,301N, 1,304K, 1,335V, 1,337D, 1,339G, 1,341G, 1,342F, 1,425G, 1,426L, 1,427G, 1,428L, 1,444C, 1,446S, 1,451G, 1,452S, 1,454F
CDD
cd00075 (HATPase_c)
Mg2+ binding site ...

1,301N

Mg2+ binding site
1,301N
CDD
cd00075 (HATPase_c)
G-X-G motif cd00075

1,339G

G-X-G motif
1,339G, 1,341G, 1,425G, 1,427G
CDD
cd00075 (HATPase_c)

1,341G

G-X-G motif
1,339G, 1,341G, 1,425G, 1,427G
CDD
cd00075 (HATPase_c)

1,425G

G-X-G motif
1,339G, 1,341G, 1,425G, 1,427G
CDD
cd00075 (HATPase_c)

1,427G

G-X-G motif
1,339G, 1,341G, 1,425G, 1,427G
CDD
cd00075 (HATPase_c)
active site cd00156

1,689E

active site
1,689E, 1,690D, 1,736D, 1,744G, 1,775S, 1,794Y, 1,797K, 1,798P
CDD
cd00156 (REC)

1,690D

active site
1,689E, 1,690D, 1,736D, 1,744G, 1,775S, 1,794Y, 1,797K, 1,798P
CDD
cd00156 (REC)

1,736D

active site
1,689E, 1,690D, 1,736D, 1,744G, 1,775S, 1,794Y, 1,797K, 1,798P
CDD
cd00156 (REC)

1,744G

active site
1,689E, 1,690D, 1,736D, 1,744G, 1,775S, 1,794Y, 1,797K, 1,798P
CDD
cd00156 (REC)

1,775S

active site
1,689E, 1,690D, 1,736D, 1,744G, 1,775S, 1,794Y, 1,797K, 1,798P
CDD
cd00156 (REC)

1,794Y

active site
1,689E, 1,690D, 1,736D, 1,744G, 1,775S, 1,794Y, 1,797K, 1,798P
CDD
cd00156 (REC)

1,797K

active site
1,689E, 1,690D, 1,736D, 1,744G, 1,775S, 1,794Y, 1,797K, 1,798P
CDD
cd00156 (REC)

1,798P

active site
1,689E, 1,690D, 1,736D, 1,744G, 1,775S, 1,794Y, 1,797K, 1,798P
CDD
cd00156 (REC)
phosphorylation si...

1,736D

phosphorylation site
1,736D
CDD
cd00156 (REC)
intermolecular rec...

1,739M

intermolecular recognition site
1,739M, 1,740P, 1,742K, 1,743N, 1,744G
CDD
cd00156 (REC)

1,740P

intermolecular recognition site
1,739M, 1,740P, 1,742K, 1,743N, 1,744G
CDD
cd00156 (REC)

1,742K

intermolecular recognition site
1,739M, 1,740P, 1,742K, 1,743N, 1,744G
CDD
cd00156 (REC)

1,743N

intermolecular recognition site
1,739M, 1,740P, 1,742K, 1,743N, 1,744G
CDD
cd00156 (REC)

1,744G

intermolecular recognition site
1,739M, 1,740P, 1,742K, 1,743N, 1,744G
CDD
cd00156 (REC)
dimerization inter...

1,797K

dimerization interface
1,797K, 1,798P, 1,799I
CDD
cd00156 (REC)

1,798P

dimerization interface
1,797K, 1,798P, 1,799I
CDD
cd00156 (REC)

1,799I

dimerization interface
1,797K, 1,798P, 1,799I
CDD
cd00156 (REC)

Protein sequence

>MIA_04264_1
MPTPRKQESSSSQKIPLPHYQETLMNQQISASAQAMGSFTASASAAASSGVSGQTIVGKIATNNTTNAANATTSSAPNQP
SKPTIKFPPNHIPLSPDPLSPFYIPLAKSSSSKSPAGNLKVLQQPQTHPSSSFSLPALTTLPFSSGPINPIDLPSLILAL
NLESEFDSFFNTLVDILQSLFSATRVSLALPNDPADIYNAPWGLKGLWNGESDLPSPSSQSSSSSSKHSETPRHSIDTIN
ISLNTSSNNDLDDSSWDTEDIMSDIEDEDEDDSLLLISQSKPPTTALSKNTESNPTDATNPARPDPTQRVASPFNYVPLY
SSSLNSLYQEDVDLITENFTRSAASTHPQNPSMDINAAETTAAAIATQQPLASSSAPTTISSHAHTQPLQPPPHLEKPVS
LRQKLTRRLSKSKRNKPDDPLSIPKIEVGVAAATPSINLPLDSESNNLPSPPPPPPTHAATNTPTVAATNNQTPSLKKGK
HKHSSSVSSNGSTSRGGNNRGSYSQNHSQTYASSSAFTYQNFPRHSTNNRFSNLSTKSQLLPNLVVFDELQSLAWERDPL
IDSSSISKIIKCGAATLLQRKYSPNGDVLAPPKYEEKIYFDSEQTMNSPWSCSPAPSPAIHDSQENPFFKDYALSPKSTT
CRKSSESSELESAFSQGSDSDTSFSDYTKKLHDPPFLLSGIKESVSAIGCENTVSIIHIPLIVPTKVSINKFLGKMEYKN
TSPPIAVLSIMSPLIPYPGDLSEHLKQFSSHIATALVNAKAHTNLSNQIDSISFSSSLSSRPPPYHHNHHYHHHHRLSAG
STATSYSGSSSLQSPTSTISPEKSARSTRHRERLKRVGSFAFKYGYAKRLSYSSTNSATASKEDDNKDTEEEHPSHHRPS
LLSNPSSLRSLLPVRHLRKILESIPIQIYTMEPVGGNICWVSNRVTSYRGQTYEEFCANPYKSIHPKDRDDFLSLLHEAF
RTGEAFSRMVYLRRFDGAYRATIYRCYPLRDDRGVTAFWLCTLFDVHQQRKAELAAIKRAKQTAGDHKYKILAESTPIIV
FTFHRSRGIVYSNKAWFDFSGCNAEKTYGFEYVKRIHPEDRERCLIQADMLKKHTPKDEWSIKNVPPKGSYTVEARLLDK
NNQYIWHLITYTSVDAEDLEDGMWFGTCTNINDQKLNQAKLLEDKEEAQRTIESKTIFLSNMSHEIRTPLIGISGMVRFL
FDTPLTAEQLDYCHTISSSSDALLNVINDILDLSKVESGKMTLTSSWYHVRRLLEEANEFLSSMAISKSLELNYMIEDDV
PMWVKGDRFRLRQVMLNLIGNAIKFTNKGEVFTRCSVVKEDKTKPSNTVLLKFEVIDTGRGFTSEDELRMFKPFSQLRSN
HQYQDYSDGPSLSSSSSFSSSSSSSSSSSSTCSSGSSTSTAKVPFEEPKIEPILAPPTFTSPGTGLGLVISRQLIQLQGG
ELTCKSKPGKGSKFVFTCRVSLPTESDKPPVEESMQVEEEVIVSEAQPLDILIICPCEYAPLSIIHHIKKTVADPVNCQC
TVVKNDNILREYISGKKPFRRWTHVIINNSKSELVETAKLALECNRRFQWMMEIVLLVPLIQESTIIAGINGVGAVGQQK
LPPSIRVLHKPVTPTKYSLVFDPSKQREASRDLKMRNAQEVLENQKDIFKTIQRFVGDRRKDDEAGGAGRSSNGKLKTEE
GPMRVLLAEDNPVNQKVMGRFFDKAGLEYEIARDGVECTRKVFEHARGYYGLIICDLDMPRKNGFETCKEIREWERQQDA
ATGKPECPVAIVALSAYVMSDMAGQCDQVGFTRYISKPIDFGRLKDLILELLS

GO term prediction

Biological Process

GO:0000160 phosphorelay signal transduction system
GO:0007165 signal transduction
GO:0016310 phosphorylation

Molecular Function

GO:0000155 phosphorelay sensor kinase activity
GO:0005515 protein binding
GO:0016772 transferase activity, transferring phosphorus-containing groups

Cellular Component