Protein

MIA_04259_1

Length
823 amino acids

Browser: contig05:1216272-1218744+

Protein function

EGGNOG:0PGTTPKH3serine threonine protein kinase
SGD closest match:S000005460PKH2Serine/threonine-protein kinase PKH2
CGD closest match:CAL0000187991PKH2Serine/threonine-protein kinase PKH2

Protein alignments

%idAln lengthE-value
MCA_04953_164.322%3985.10e-170MCA_04953_1
A0A167C8X5_9ASCO64.431%3432.77e-143Serine/threonine protein kinase PKH2 OS=Sugiyamaella lignohabitans GN=PKH2 PE=4 SV=1
UniRef50_A0A167C8X564.431%3437.60e-140Serine/threonine protein kinase PKH2 n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167C8X5_9ASCO
A0A1E3PGW1_9ASCO61.798%3566.15e-140Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83515 PE=4 SV=1
Q6CFM7_YARLI64.327%3421.03e-134YALI0B05566p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B05566g PE=4 SV=1
A0A060SYZ5_BLAAD65.538%3257.36e-138ARAD1C01276p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C01276g PE=4 SV=1
A0A0J9X399_GEOCN61.628%3441.63e-137Similar to Saccharomyces cerevisiae YDR490C PKH1 Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis OS=Geotrichum candidum GN=BN980_GECA01s10020g PE=4 SV=1
A0A1E4TEU0_9ASCO62.712%2953.41e-118Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31248 PE=4 SV=1
PKH2_CANAL55.263%3421.29e-110Serine/threonine-protein kinase PKH2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PKH2 PE=1 SV=2
PKH2_YEAST52.475%3035.85e-100Serine/threonine-protein kinase PKH2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PKH2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0812

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 823

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. cd05581 (STKc_PDK1)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd05581
  3. polypeptide substr...
  4. activation loop (A...

Protein sequence

>MIA_04259_1
MASQDPMPRSAQEWREHGATTFVHQKVDSQGKVHTVTIKKGVNSFNFGRTLGIGSYSTVVCASDKETRREYAIKILNKIH
IIKEKKVKYVEIEKQTLNRLGNYPGVIPLYYTFQDEQSLYFVLDFAANGELLSLIKRLGSLSEECVRYYGAQLLDAVDFM
HSRGVLHRDLKPENILLDKYMRIKVTDFGTAYLVNHERDSEGNELDTYPQTTSAKSFVGTAEYVSPELLNQKAVTKACDV
WAYGCIIYQMLAGHPPFKGDNEYQTFQKIVKLQYSYPPHFPTVLRDLIKHILILDPSRRFTSAHIKEHSFFDGQDWSRSA
IWKTAHPRLLPYRHQPRTVSNPLSRIARPGTINPNLRARANGNGPGPSAYGQSIARSKSANPRASNSTPNLLNMGASAAA
GAAAALAKTPSSISPYPTPTQQYSGKPVPVFVSNKPTPNSNSNNSSSQISSSSSSQQQTPASPASRNIPRVPVVRSTKSQ
QLSNIQVSKTTPASSSPSQPLQSPMSPSQQLQNNNNSSGSASVPKPIVAPLAPPTPPVITASVSAPSSPVTTATAAPTSA
APPPSNTPAVKLLEIPPLSNTDRELQSLLTTKDERILKISNVTMSITSANSVHQQSPEGNGSSSSGSNGKKSQDDGTAYE
EEFNGREPSRISRLFAGSRKKKRIMFVTTLGRLVVISSVEDKKVHLDIRVVAPQVVVREFAHNRKNNVGVFAIEAHNKVF
TFEDQGGSADWMTSFAKARAYVENAEAVNASKTHMTAAAAAMAAAASSALRSGTVGIGGTLGAHSQQSQSYGGRASSDLD
GIVNENTSMFLKRHEERKLRKII

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.