MIA_04251_1

Protein

Length

1,669 amino acids

Browser: contig05:1196003-1201041-

Protein function

EGGNOG:	0PKA3		reverse transcriptase
SGD closest match:	S000007261	AI1	Putative COX1/OXI3 intron 1 protein
CGD closest match:	CAL0000176110	orf19.7274	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MCA_03180_1	39.640%	1057	0.0	MCA_03180_1
A0A167E5I2_9ASCO	35.574%	1071	0.0	Polyprotein of L1-like non-LTR retrotransposon Zorro 3 OS=Sugiyamaella lignohabitans GN=POL92 PE=4 SV=1
UniRef50_A0A167E5I2	35.574%	1071	0.0	Polyprotein of L1-like non-LTR retrotransposon Zorro 3 n=7 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167E5I2_9ASCO
A0A0J9XC44_GEOCN	28.968%	252	8.10e-22	Uncharacterized protein (Fragment) OS=Geotrichum candidum GN=BN980_GECA08s04349g PE=4 SV=1
A0A1D8PFY7_CANAL	25.926%	270	9.51e-14	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7274 PE=4 SV=1
A0A060T0U2_BLAAD	52.000%	50	7.72e-09	ARAD1C18194p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C18194g PE=4 SV=1
AI1M_YEAST	25.828%	151	2.39e-06	Putative COX1/OXI3 intron 1 protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AI1 PE=4 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0178

Protein family membership

None predicted.

Domains and repeats

Domain
584 - 820
Endonuclease/exonuclease/phosphatase (IPR005135)
1,077 - 1,347
Reverse transcriptase domain (IPR000477)

1 200 400 600 800 1000 1200 1400 1669

Detailed signature matches

IPR005135

Endonuclease/exonuclease/phosphatase
1. SSF56219 (DNase I-like)
  
  602 - 817
  
  SUPERFAMILY
  SSF56219 (DNase I-like)
2. G3DSA:3.60.10.10
  
  584 - 820
  
  GENE3D
  G3DSA:3.60.10.10 (G3DSA:3.60.10.10)
3. PF14529 (Exo_endo_p...)
  
  697 - 812
  
  Pfam
  PF14529 (Exo_endo_phos_2)
IPR000477

Reverse transcriptase domain
1. PF00078 (RVT_1)
  
  1,099 - 1,346
  
  Pfam
  PF00078 (RVT_1)
2. PS50878 (RT_POL)
  
  1,077 - 1,347
  
  PROSITE profiles
  PS50878 (RT_POL)

no IPR

Unintegrated signatures

Coil

177 - 218

COILS
Coil (Coil)

297 - 317

COILS
Coil (Coil)

865 - 885

COILS
Coil (Coil)

901 - 921

COILS
Coil (Coil)
G3DSA:1.20.12...

153 - 391

GENE3D
G3DSA:1.20.120.330 (G3DSA:1.20.120.330)
G3DSA:3.30.70...

1,147 - 1,347

GENE3D
G3DSA:3.30.70.270 (G3DSA:3.30.70.270)
SSF56672 (DNA/RNA p...)

1,039 - 1,284

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)
cd01650 (RT_nLTR_like)

1,090 - 1,347

CDD
cd01650 (RT_nLTR_like)
mobidb-lite (disord...)

96 - 136

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 23

MobiDB Lite
mobidb-lite (disorder_prediction)

52 - 75

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative NTP bindi...

1,176D

putative NTP binding site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,267D
CDD
cd01650 (RT_nLTR_like)

1,177I

putative NTP binding site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,267D
CDD
cd01650 (RT_nLTR_like)

1,178Q

putative NTP binding site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,267D
CDD
cd01650 (RT_nLTR_like)

1,179G

putative NTP binding site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,267D
CDD
cd01650 (RT_nLTR_like)

1,180A

putative NTP binding site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,267D
CDD
cd01650 (RT_nLTR_like)

1,181F

putative NTP binding site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,267D
CDD
cd01650 (RT_nLTR_like)

1,235Q

putative NTP binding site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,267D
CDD
cd01650 (RT_nLTR_like)

1,267D

putative NTP binding site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,267D
CDD
cd01650 (RT_nLTR_like)
putative active si...

1,176D

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,177I

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,178Q

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,179G

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,180A

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,181F

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,235Q

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,236G

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,265F

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,267D

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,268D

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,343L

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)

1,344G

putative active site
1,176D, 1,177I, 1,178Q, 1,179G, 1,180A, 1,181F, 1,235Q, 1,236G, 1,265F, 1,267D, 1,268D, 1,343L, 1,344G
CDD
cd01650 (RT_nLTR_like)
putative nucleic a...

1,236G

putative nucleic acid binding site
1,236G
CDD
cd01650 (RT_nLTR_like)

Protein sequence

>MIA_04251_1
MPDPPDKNNPTTPSGNDPRADINNLDNHVEQTKINDIEKTIAVGLKQKGVSHLKGHHSHDVHHVKASPKIHKDDDKIDKI
ANLDKLQKKLDHLNKHPDYEHQENDPDSQMLDTTSDPDSPTENFSSGGDTEIDANNSRDIDINMADNITITPTHEIESVN
CISETLVAKVNSLAEILVMVNNKYDNMEKNCQSLKKENELLKKESEILTAENAVLRNKFVEFSLKFDQFEGSWNTLRSEV
DNLKSKEVHSEVKKITIEQIKKDVKANHDHCVRNSQKAEELANLAITDWTQRAAENKQTVKKEINHVKEITQNLEKRIDG
IEYQVGTISTKTDLASKEITYAKQEIKSAVRKVDTLPYKLTTRPSNSNPIKLKDIMKAQKQQREEQVANAKPIYRVCIRI
PATANNIRRETIGAKIDSIAQKNVAEMVEFTTKGNLYVNINDKEFADRAAEWIPQIDPTFSLLDTEPWYKAKLLGVPEEA
TIQEVKDALYTFGEYHIVLNNEPKVIYKNHDSQTILVCFRNVSDFAKCADKLVIRYTKIKVTPYVNRPKTPEQLQRIQMK
NKKTKRLQMRNPQKNLWMTQKLKNSWNLLQKKPQLLRIPLMIYKVFQLNCHKSKSITETILDEKEPDILLLQEPYFSKYG
PINHKEWIPIYAIAQNGNAPYRAITYIRSNSDLRAVTTKIEKLTNTDMVTIMVKDFTLVNVYNQPKPSKKFPEPPALEIL
KKEVQGQYDKLIIAGDYNLHHREWETESNPDADTNEIVDWLHENDMMLITPPNRKTYRNKTTIDLVYCSVHLLHRIIFRK
IDENSLSDHAIVEWDLSFFQHQHEEEKLTSIERLNIQQANWDKFEQELSNAIKTLNVHDKALKSLDQIDSQAEILENVIK
KAMASSMEKIKLVRKSKRYWNAELRKKLEFALKAKREARLRQPTFALKKQKIQEAKEATRDFDRSLREASSEQWNKFLSD
LERNDIWRVLRYINPKGNDTIIPQIRKEDGTLTTTVEEKRHEIWKALLPEIDHGPDKYFEIDDDSRWPKLDIKEVEIALA
NTPNDKAAGDDGITGLVLKKAWKNKDYQIRFFKLLQACVNFGYHPKVWRHGIIVVIPKPKKPDYSKPRAYRPISLLKIPS
KVLEKIMQTRMTKLTDKLLPPEQYGGRKGYCATDAVLELVQRIETSREKISAILIDIQGAFDNVNRNILAETMENMGLPN
ALISWTYQFISQREASILMDRRKGPVQKISTGIPQGSPISPLLFLIYSTPMYKAIQQWGGKAFGFIDDVTITVEGTIDKN
TELLSNILAKCCEGAKSRMTKIDLGDKLGFIHFAKNIKANDQKAQLTLPNGKHLKPQKEVKLLGIILNNTLDFKSHIMSK
ITKARKAIGAIWRLGGTLRGMRGSSVRSLYIACVRPIIEYGMEIWFHKILKGEIHKLEVAQNMALRRVVGAYRTTPIAVL
QKEAGVMPYNIRLNFMIARKAIRLHLNISNTNPIKEHLLTLIENSPIAKLTSVYLEAEEDRKVVIKNLMKTRKKPVFGPV
TRELLQSQLIAILKKQAIEKWRDAYWHSKKDQWYHDITAETPCSDNLSKMTTGVVMKKDSRRTLSFITQFRTGHGNFGAW
FKKFGIQKDSYDCECGELETVRHILVECPLLEEKRKGLRRISPEMDMSTLLNSLTGLQEIARFISVWRE

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MIA_04251_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component