Protein

MIA_04249_1

Length
237 amino acids

Browser: contig05:1191146-1191926-

Protein function

EGGNOG:0PK76PGUG_04223pyridoxamine 5'-phosphate oxidase
SGD closest match:S000000239PDX3Pyridoxamine 5'-phosphate oxidase
CGD closest match:CAL0000195497PDX3Pyridoxamine-phosphate oxidase

Protein alignments

%idAln lengthE-value
MCA_06401_175.446%2242.14e-126MCA_06401_1
A0A0J9XK01_GEOCN64.000%2254.27e-108Similar to Saccharomyces cerevisiae YBR035C PDX3 Pyridoxine (Pyridoxamine) phosphate oxidase OS=Geotrichum candidum GN=BN980_GECA20s01715g PE=3 SV=1
A0A060THL3_BLAAD63.721%2151.44e-100ARAD1D39204p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D39204g PE=4 SV=1
A0A1E3PHQ8_9ASCO62.222%2255.44e-95Pyridoxamine 5'-phosphate oxidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51537 PE=3 SV=1
PDX3_YEAST57.991%2191.48e-88Pyridoxamine 5'-phosphate oxidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PDX3 PE=1 SV=1
UniRef50_P3807557.991%2193.53e-85Pyridoxamine 5'-phosphate oxidase n=44 Tax=Ascomycota TaxID=4890 RepID=PDX3_YEAST
Q6C946_YARLI55.204%2211.87e-84YALI0D14322p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D14322g PE=3 SV=1
A0A1D8PSU2_CANAL54.393%2397.49e-83Pyridoxamine-phosphate oxidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PDX3 PE=4 SV=1
A0A1E4TC54_9ASCO51.570%2236.12e-75Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3959 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0470

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 237

Detailed signature matches

  1. Family IPR000659
    Pyridoxamine 5'-phosphate oxidase
    1. PIRSF000190 (Pyd_am...)
    2. TIGR00558
    3. MF_01629 (PdxH)
  2. Domain IPR012349
    FMN-binding split barrel
    1. SSF50475 (FMN-bindi...)
    2. G3DSA:2.30.11...
  3. Domain IPR011576
    Pyridoxamine 5'-phosphate oxidase, putative
    1. PF01243 (Putative_P...)
  4. Domain IPR019576
    Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal
    1. PF10590 (PNP_phzG_C)
  5. SITE IPR019740
    Pyridoxamine 5'-phosphate oxidase, conserved site
    1. PS01064 (PYRIDOX_OX...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil

Protein sequence

>MIA_04249_1
MADHAAFTRTEDPSKEEAVIFAPKTHQYSKFSLDKADLTQEPSDQFLKWFKEAQETPTIPIPEAVTLSTARLPSGRVSSR
VVLFKELDKDGSLVIYSNWDTSKKNSDIRSNPLAAINFFWPQLERQVRVEGPTEFLTNEESQIYFNTRPKDSRIGAWASP
QSVRVTDRQELEDRVKEQQERFKDVDIVPCPPKWGGLRIKPVEWEFWQGRPNRVHDRYSYTRETPEDSTWEVNRLGP

GO term prediction

Biological Process

GO:0008615 pyridoxine biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004733 pyridoxamine-phosphate oxidase activity
GO:0010181 FMN binding
GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors
GO:0048037 cofactor binding

Cellular Component

None predicted.