Protein

MIA_04218_1

Length
847 amino acids

Browser: contig05:1100585-1103156-

Protein function

EGGNOG:0PGD3RAS1Ras-like protein
SGD closest match:S000005627RAS1Ras-like protein 1

Protein alignments

%idAln lengthE-value
A0A0J9XJ76_GEOCN54.762%1685.30e-55Similar to Saccharomyces cerevisiae YOR101W RAS1 GTPase involved in G-protein signaling in the adenylate cyclase activating pathway OS=Geotrichum candidum GN=BN980_GECA18s01682g PE=4 SV=1
UniRef50_A3LU8557.927%1642.51e-50Uncharacterized protein (Fragment) n=9 Tax=Eukaryota TaxID=2759 RepID=A3LU85_PICST
A0A060TCD6_BLAAD55.758%1652.66e-51ARAD1B22924p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B22924g PE=4 SV=1
A0A1E4TBI2_9ASCO54.321%1625.95e-51Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_132871 PE=4 SV=1
RAS1_CANAL53.846%1692.72e-50Ras-like protein 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RAS1 PE=3 SV=2
A0A167EDF5_9ASCO46.119%2196.87e-50Ras family GTPase RAS1 OS=Sugiyamaella lignohabitans GN=RAS1 PE=4 SV=1
MCA_05640_145.274%2011.29e-44MCA_05640_1
RAS1_YEAST53.086%1623.82e-48Ras-like protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAS1 PE=1 SV=2
Q6C6K7_YARLI52.096%1677.11e-45YALI0E08756p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E08756g PE=4 SV=2
A0A1E3PPR0_9ASCO46.857%1751.06e-39Ras-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49355 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7878
Predicted cleavage: 18

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 847

Detailed signature matches

  1. Family IPR001806
    Small GTPase superfamily
    1. PF00071 (Ras)
  2. Family IPR020849
    Small GTPase superfamily, Ras type
    1. PS51421 (RAS)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.70...
  3. G3DSA:3.40.50...
  4. PR00449 (RASTRNSFRMNG)
  5. SM00173 (ras_sub_4)
  6. SM00174 (rho_sub_3)
  7. SM00175 (rab_sub_5)
  8. SM00176 (ran_sub_2)
  9. cd00876 (Ras)
  10. mobidb-lite (disord...)

Residue annotation

  1. G1 box cd00876
  2. GTP/Mg2+ binding s...
  3. GEF interaction si...
  4. Switch I region cd...
  5. G2 box cd00876
  6. effector interacti...
  7. G3 box cd00876
  8. Switch II region c...
  9. GDI interaction si...
  10. G4 box cd00876
  11. G5 box cd00876

Protein sequence

>MIA_04218_1
MVVSNYFHIFLLHINRFVVGGGGVGKSSLTIQLIEGTFLEEYDPTIEDSYRKQCTIDDGPDTLALPVVLEVLDTAGQDEY
NALRENYIKTGEGFLLVYDVTSRYSFEEVQKLYKQICTVKDRENTPIVLLGNKTDIAEAEPEKRQVSRAEGLIMAKKFGK
SVVFWETSARMRQHVQEAFFDLVRLIRRQNMEPAIPLNRVIGHIHTSALNVRPPSPNDHPTDLSPTSVIRKVASKASLRS
TNTVFSTARKLSNSSSFSNLYNGSNNKSNFNLANESGSINSNSSSHGNVNDGKGFSNLASAFGTGASRILSFTLGRTNNN
GPERMGAHKISPEKELRSKKSRSELFSRGRYYSQVYNQHQASPQSPTMPRKLRRQSDNVTGTNTDTKNVFFTNEPNSTCH
LYGSLLENNQRIKSNSGSGPSSSKNLKSAISHQQLSNSCSARPSISHRKSMPQLLDSKERRPRPDKKQYYVEPPLPPLPK
EAALAPGLFETPTNGPIPSTPLTLPSPLSPKAYMPVPPSPCSPTSDTHQTTPLLSLVIPTKFEQFPVTPDSPSGNGFGDC
ISRTFNKLKSRIIKSRANSAPEPDTQNEMPETFIKRRASLERGNKIHQIAESLEELHSDMSLTTQVSSNSTLSAITSASH
SASIQKQLMQKQHQKHFLVSPSSQSSLQNELQKALLSSSEPVPQLHPPQLPQLSLLPQLPLFSQLSLETSQNSCHHQSPK
HISPHKLDAPLPPLPQVTEVSTDSSPTKAINKSPDYRQKTCKIKYSKYQDRYSQQYQQYQKMLQMKEQALKKSNEMNKEM
LNREQCKKKPQQSDEPGQQDELQCYYRQPHLNSPQEPASPHGITMGY

GO term prediction

Biological Process

GO:0007165 signal transduction

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

GO:0016020 membrane