Protein

MCA_05640_1

Length
896 amino acids

Gene name: RAS1

Description: Ras family GTPase RAS1

Browser: contigD:1897791-1900575+

RNA-seq: read pairs 966, FPKM 13.3, percentile rank 31.4% (100% = highest expression)

Protein function

Annotation:RAS1Ras family GTPase RAS1
EGGNOG:0PGD3RAS1Ras-like protein
SGD closest match:S000005042RAS2Ras-like protein 2

Protein alignments

%idAln lengthE-value
MIA_04218_145.27%2013e-44MIA_04218_1
A0A0J9XJ76_GEOCN46.95%2132e-47Similar to Saccharomyces cerevisiae YOR101W RAS1 GTPase involved in G-protein signaling in the adenylate cyclase activating pathway OS=Geotrichum candidum GN=BN980_GECA18s01682g PE=4 SV=1
RAS2_YEAST46.88%2247e-47Ras-like protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAS2 PE=1 SV=4
UniRef50_A3LU8547.44%2152e-44Uncharacterized protein (Fragment) n=9 Tax=Eukaryota TaxID=2759 RepID=A3LU85_PICST
A0A1E4TBI2_9ASCO45.83%2163e-45Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_132871 PE=4 SV=1
A0A060TCD6_BLAAD46.48%2136e-44ARAD1B22924p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B22924g PE=4 SV=1
A0A167EDF5_9ASCO46.51%2156e-43Ras family GTPase RAS1 OS=Sugiyamaella lignohabitans GN=RAS1 PE=4 SV=1
RAS1_CANAL48.13%2147e-42Ras-like protein 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RAS1 PE=3 SV=2
Q6C6K7_YARLI44.34%2129e-40YALI0E08756p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E08756g PE=4 SV=2
A0A1E3PPR0_9ASCO41.90%2103e-33Ras-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49355 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0855

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 896

Detailed signature matches

  1. Family IPR001806
    Small GTPase superfamily
    1. PF00071 (Ras)
  2. Family IPR020849
    Small GTPase superfamily, Ras type
    1. PS51421 (RAS)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.70...
  2. G3DSA:3.40.50...
  3. PR00449 (RASTRNSFRMNG)
  4. SM00173 (ras_sub_4)
  5. SM00174 (rho_sub_3)
  6. SM00175 (rab_sub_5)
  7. cd00876 (Ras)
  8. mobidb-lite (disord...)

Residue annotation

  1. G1 box cd00876
  2. GTP/Mg2+ binding s...
  3. GEF interaction si...
  4. Switch I region cd...
  5. G2 box cd00876
  6. effector interacti...
  7. G3 box cd00876
  8. Switch II region c...
  9. GDI interaction si...
  10. G4 box cd00876
  11. G5 box cd00876

Protein sequence

>MCA_05640_1
MVVLREYKLVVVGGGAVGKSALTIQLTQNQFCHEYDPTIEDSYRKHETLYEFEEQHTHKRFFVEPSLQKRNQNSSQDKFP
TYKVNPIPIMLDILDTAGQEEYSAMKEQYIRNGEGFLLVYAVSSYESFAEIEIIYRTICKVKDRKNTPIAIIGNKCDVQP
NERQVSYQQGLELAMKIAKSHRSDNKISNVLFMETSAKSNNNVASAFLDVVKLIRRDSSDLKKYYSELFSKFEVHPEQGI
ITTTFEDIERIELEKRESSNNDNSSKTKEQSKGIGNINEKFKYMSKSRSRSVNTSSNNNKNIDPSSNSEDTNRNNNSVNI
NNANSSNKGKNLNLNIPEKNTVVRKVKSRSSLKNSPTSPNFNIFRRTSGNWFSSPSKSKNGNEPLFETPFKSLDLKTINT
TPDQTSPTSKSFSSSNQASRDPETTVNSVPEIKEDKEIKEIKDIKEIRETVETEAKNTIAAVKSLSISHNEMNFITQPRH
SIKPKLVSHQPHSSSSSFLKTESRANMESSVIASFDFDTTNLSSYNYYGSNNVWLNARTAIDNSNSDSNSSIVANSKEDS
SANANSLNATNSKKQGSVAGPKSINSPHNISKHTSRQRRNSSTSTSNSNASYKSHISHGSNTSNVSTAPTICNDFTESTT
VNTNLSVYSKNNSPNADSHPNKAVITSIESKSAYRSFSNYKAQPLSSGTTMNGSDTYYDEDSDDYDIYEFTMDFNPSFGG
SNPSISSSQSAPVGSDSKTRGFFLSRKSKSSSYQRRMSRLSFRKHSSFLSLSTTESTGLKDTFGLSTQKQNQNSESPESI
NESTKTGVSAPALQKATTTTTTTQPQLSKKSKIALYRTFSNKLLDKCDEQDLRNITSRSGSIASMPADIAFSQEKSTQAF
DETFSTEKQVSGCKVS

GO term prediction

Biological Process

GO:0007165 signal transduction

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

GO:0016020 membrane