Protein

MIA_04208_1

Length
977 amino acids

Browser: contig05:1076698-1079777-

Protein function

EGGNOG:0PI91FGSG_01612vacuolar protein sorting protein
SGD closest match:S000004844PEP5E3 ubiquitin-protein ligase PEP5
CGD closest match:CAL0000200561VPS11Tethering complex subunit

Protein alignments

%idAln lengthE-value
MCA_05431_172.110%9860.0MCA_05431_1
A0A0J9YH84_GEOCN63.764%9990.0Similar to Saccharomyces cerevisiae YMR231W PEP5 Component of CORVET tethering complex OS=Geotrichum candidum GN=BN980_GECA01s00725g PE=4 SV=1
A0A060T7V4_BLAAD52.594%9830.0ARAD1B23100p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B23100g PE=4 SV=1
A0A167C3E8_9ASCO53.070%9610.0Tethering complex subunit PEP5 OS=Sugiyamaella lignohabitans GN=PEP5 PE=4 SV=1
UniRef50_A0A167C3E853.070%9610.0Tethering complex subunit PEP5 n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A167C3E8_9ASCO
A0A1E3PLU6_9ASCO46.533%9950.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_69604 PE=4 SV=1
Q6C4V4_YARLI44.264%9850.0YALI0E23408p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E23408g PE=4 SV=1
A0A1E4TLA2_9ASCO34.385%9830.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_88871 PE=4 SV=1
A0A1D8PMF6_CANAL34.587%10900.0Tethering complex subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VPS11 PE=4 SV=1
PEP5_YEAST32.670%10561.13e-157E3 ubiquitin-protein ligase PEP5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEP5 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0322

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Repeat
1 100 200 300 400 500 600 700 800 900 977

Detailed signature matches

  1. Family IPR016528
    Vacuolar protein sorting-associated protein 11
    1. PIRSF007860 (Vps11)
  2. Domain IPR015943
    WD40/YVTN repeat-like-containing domain
    1. G3DSA:2.130.1...
  3. Domain IPR017986
    WD40-repeat-containing domain
    1. SSF50978 (WD40 repe...)
  4. Domain IPR011990
    Tetratricopeptide-like helical domain
    1. G3DSA:1.25.40.10
  5. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  6. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
  7. Domain IPR001841
    Zinc finger, RING-type
    1. SM00184 (ring_2)
    2. PS50089 (ZF_RING_2)
  8. Domain IPR024763
    Vacuolar protein sorting protein 11, C-terminal
    1. PF12451 (VPS11_C)
  9. Repeat IPR000547
    Clathrin, heavy chain/VPS, 7-fold repeat
    1. PS50236 (CHCR)
    2. PF00637 (Clathrin)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF57850 (RING/U-box)
  2. cd16688 (RING-H2_Vps11)
  3. mobidb-lite (disord...)

Residue annotation

  1. Zn binding site cd...

Protein sequence

>MIA_04208_1
MSITTWRYFNFFDATPIKDPSLADEHTLYSDPGLTAITPGLNTIFFATSNAVIKEFSQDLTLKQSWTAYEPTASISYLRY
LKGTSLLLSVGETSGIAPVIKLWNLEKRDKKTGFPHLHSTVSVSNGDNISPISSFDITSDHSLLAFGFADGTVILVRGDI
VHDRGARQRVVYDSNGPVTGLAFCENKAENMATLFVATVNRIFTVSTTGKNNGKPEKVLDKSRGADLGCTTFDPIKQMFV
VARSDSVSYYTTTGRGPSFVFEISKKRVFTYKQYVAMVSFGGTPSSESGVSLSNLLGSVDELFTTSRLLIVDGANQYIAY
TGQISGGIKDIFVQWNKLLVLGADGVLYQFEEKSLQARLDILTGRNLYDVAIQLGKSLNIDREIILKIEKEYGDYLYKID
DVVDALPHYIQAIDLGKTSEIILKYRESQYILQLTEYLEALHDKGLAQKEHTTLLLNSYAKLKNHIKLQEFIENDSNSSK
FDFETAIQICRQSEYYDMACELAKKMGEPQLVVQIKLKDLQDYKGALSYVHSLPVDECLRILIQNSRVLLNKFPNETTLL
LIDLFTGKYVPKLEQDATKTIQSDTKDDDDSAYIAAPVLQSYRAFVNYMSLAASEEEGKDQGSVASDAQADENSTEDPPT
YQPPRPRLIFSSFVDHPNEFVIFLEACLEAYEKFSGNEKDRTDILSTLYEMYLELSKDSPDKKEWEDKAKALATESAKSL
DPNTILLLSHLANFSEGELFSKDQEGFQTDLFRSCVAMSDVPGAIHVLKKYGDSEPELYPLALTFFTSSPSILEEAGNEF
EYVLNKIKDEKLMAPLQVVQALSVNSVATVGLVKQYLIDLIEREKSEIDTNLKLSASYRAETQTKQAEIDHLKRDPQVIQ
YTSCSACGSALDLPAVHFGCKHSFHQRCLHSADEANPSCPICLPAVEAIAAIRRGQDDTSDRYDLFKMALDESESKFKVV
TDFLGRGAMEQARYILR

GO term prediction

Biological Process

GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport

Molecular Function

GO:0005488 binding
GO:0005515 protein binding

Cellular Component

None predicted.