Protein

MIA_04200_1

Length
470 amino acids

Browser: contig05:1047884-1049297+

Protein function

EGGNOG:0PFD1CIT1citrate synthase
SGD closest match:S000005284CIT1Citrate synthase, mitochondrial
CGD closest match:CAL0000197786CIT1Citrate synthase

Protein alignments

%idAln lengthE-value
MCA_04940_187.660%4700.0MCA_04940_1
A0A0J9XKN3_GEOCN85.593%4720.0Citrate synthase OS=Geotrichum candidum GN=BN980_GECA32s00604g PE=3 SV=1
A0A060T984_BLAAD83.864%4400.0Citrate synthase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C41954g PE=3 SV=1
PRPC_YARLI79.654%4620.02-methylcitrate synthase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0E02684g PE=1 SV=1
UniRef50_Q6C79379.654%4620.02-methylcitrate synthase, mitochondrial n=170 Tax=cellular organisms TaxID=131567 RepID=PRPC_YARLI
A0A1E3PRI0_9ASCO79.773%4400.0Citrate synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48693 PE=3 SV=1
A0A1D8PSH3_CANAL76.559%4650.0Citrate synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CIT1 PE=3 SV=1
CISY1_YEAST79.540%4350.0Citrate synthase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CIT1 PE=1 SV=2
A0A1E4THC0_9ASCO77.014%4220.0Citrate synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2869 PE=3 SV=1
A0A167C7C0_9ASCO85.382%3011.18e-174Citrate synthase OS=Sugiyamaella lignohabitans GN=CIT1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9755
Predicted cleavage: 32

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 470

Detailed signature matches

  1. Family IPR002020
    Citrate synthase
    1. SSF48256 (Citrate s...)
    2. PF00285 (Citrate_synt)
    3. PR00143 (CITRTSNTHASE)
  2. Family IPR010109
    Citrate synthase, eukaryotic-type
    1. TIGR01793
  3. Domain IPR016142
    Citrate synthase-like, large alpha subdomain
    1. G3DSA:1.10.58...
  4. SITE IPR019810
    Citrate synthase active site
    1. PS00480 (CITRATE_SY...)

Protein sequence

>MIA_04200_1
MASLVRNTFIRPSTLKMAAGRSASAFAARAYSTKEPTLKERFAELLPEKIEQIKKLRKDHGNTVIGEVLLDQVYGGMRGI
KALVWEGSVLDPEEGIRFRGRTIPDIQKELPKAPGGEEPLVEGLFWLLLTGEVPTESQVRALSAEFAARSELPNHVKDLI
DRCPATLHPMAQFTIAVAALESESSFAKAYERGVPKKEYWLYTYEDSIDLLAKLPNIAARIYRNVFKDGKLGSVDPTVDY
SQNFAHLLGFGENKEFIELLRLYLTIHTDHEGGNVSAHTTHLVASALSSPFLSLSAGLNGLAGPLHGRANQEVLEWLLEF
KKEVGNDITPEAIEKYLWKTLNAGRVVPGYGHAVLRKTDPRYTAQREFALKHMPDYDLFKLVSTIYEVAPKVLTKHGKTK
NPWPNVDSHSGVLLQYYGLTEESYYTVLFGVSRAFGVLPQVIIDRAVGAPIERPKSFSTEKYAELVGAKL

GO term prediction

Biological Process

GO:0006099 tricarboxylic acid cycle
GO:0006101 citrate metabolic process

Molecular Function

GO:0004108 citrate (Si)-synthase activity
GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

Cellular Component

None predicted.