Protein

MCA_04940_1

Length
470 amino acids

Gene name: CIT1A

Description: Citrate synthase, mitochondrial

Browser: contigC:4481151-4482797+

RNA-seq: read pairs 34738, FPKM 911.3, percentile rank 96.3% (100% = highest expression)

Protein function

Annotation:CIT1ACitrate synthase, mitochondrial
KEGG:K01647CS citrate synthase [EC:2.3.3.1]
EGGNOG:0PFD1CIT1citrate synthase
SGD closest match:S000005284CIT1Citrate synthase, mitochondrial
CGD closest match:CAL0000197786CIT1Citrate synthase

Protein alignments

%idAln lengthE-value
MIA_04200_187.66%4700.0MIA_04200_1
A0A0J9XKN3_GEOCN87.29%4720.0Citrate synthase OS=Geotrichum candidum GN=BN980_GECA32s00604g PE=3 SV=1
A0A060T984_BLAAD83.18%4460.0Citrate synthase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C41954g PE=3 SV=1
PRPC_YARLI80.74%4620.02-methylcitrate synthase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0E02684g PE=1 SV=1
UniRef50_Q6C79380.74%4620.02-methylcitrate synthase, mitochondrial n=170 Tax=cellular organisms TaxID=131567 RepID=PRPC_YARLI
A0A1E3PRI0_9ASCO78.97%4470.0Citrate synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48693 PE=3 SV=1
A0A1D8PSH3_CANAL76.13%4650.0Citrate synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CIT1 PE=3 SV=1
CISY1_YEAST78.82%4390.0Citrate synthase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CIT1 PE=1 SV=2
A0A1E4THC0_9ASCO76.54%4220.0Citrate synthase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2869 PE=3 SV=1
A0A167C7C0_9ASCO88.04%3010.0Citrate synthase OS=Sugiyamaella lignohabitans GN=CIT1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9485
Predicted cleavage: 32

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 470

Detailed signature matches

  1. Family IPR002020
    Citrate synthase
    1. SSF48256 (Citrate s...)
    2. PF00285 (Citrate_synt)
    3. PR00143 (CITRTSNTHASE)
  2. Family IPR010109
    Citrate synthase, eukaryotic-type
    1. TIGR01793
  3. Domain IPR016142
    Citrate synthase-like, large alpha subdomain
    1. G3DSA:1.10.58...
  4. Domain IPR016143
    Citrate synthase-like, small alpha subdomain
    1. G3DSA:1.10.23...
  5. SITE IPR019810
    Citrate synthase active site
    1. PS00480 (CITRATE_SY...)

Protein sequence

>MCA_04940_1
MASLIRNTFIRPSTLKMAAGRTASAVAFRSYSTKEPTLKERFAELLPEKIEQIKKLRKEHGNTVIGEVLLDQVYGGMRGI
KALVWEGSVLDAEEGIRFRGKTIPEIQQVLPKAEGGEEPLPEGLFWLLLTGEVPSDAQVKALSAEFAARAELPAHVKDLI
DRSPATLHPMAQFSIAVTALESESSFAKAYERGVNKKEYWQYTYEDSIDLIAKLPAIAARIYRNTFKDGKLGPIDPTVDY
SKNFSSLLGFGDNKEFVELIRLYLTIHSDHEGGNVSAHTTHLVGSALSSPFLSLAAGLNGLAGPLHGRANQEVLEWILEM
KSKVGSNPSAADVEKYLWDTLNAGRVVPGYGHAVLRKTDPRYTAQREFAQKHMPDYDLFHLVSTIYEVAPKVLTKHGKTK
NPWPNVDSHSGVLLQYYGLTEQSYYTVLFGVARAFGVLPQLIIDRAVGAPIERPKSFSTEKYAQLVGSKL

GO term prediction

Biological Process

GO:0006099 tricarboxylic acid cycle
GO:0006101 citrate metabolic process

Molecular Function

GO:0004108 citrate (Si)-synthase activity
GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

Cellular Component

None predicted.