Protein

MIA_04186_1

Length
639 amino acids


Browser: contig05:1013829-1015749+

Protein function

EGGNOG:0PFV7PGUG_01950phophatase 2C family protein
SGD closest match:S000005616PTC5[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
CGD closest match:CAL0000200868PTC5Type 2C protein phosphatase

Protein alignments

%idAln lengthE-value
MCA_03481_173.549%5860.0MCA_03481_1
A0A0J9X9Y6_GEOCN61.239%5650.0Similar to Saccharomyces cerevisiae YOR090C PTC5 Mitochondrial type 2C protein phosphatase (PP2C) involved in regulation of pyruvate dehydrogenase activity OS=Geotrichum candidum GN=BN980_GECA06s03475g PE=4 SV=1
A0A167ED17_9ASCO56.562%5410.0Type 2C protein phosphatase PTC5 OS=Sugiyamaella lignohabitans GN=PTC5 PE=4 SV=1
UniRef50_A0A167ED1756.562%5410.0Type 2C protein phosphatase PTC5 n=6 Tax=Saccharomycetales TaxID=4892 RepID=A0A167ED17_9ASCO
A0A060TBI9_BLAAD57.935%5230.0ARAD1B16082p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B16082g PE=4 SV=1
Q6C9Z9_YARLI50.174%5769.50e-179YALI0D07040p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D07040g PE=4 SV=1
A0A1E3PK11_9ASCO49.474%5703.74e-170Protein serine/threonine phosphatase 2C OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83303 PE=4 SV=1
A0A1E4TFL5_9ASCO50.677%5171.85e-170Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17420 PE=4 SV=1
Q5A388_CANAL46.794%5771.01e-158Type 2C protein phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PTC5 PE=3 SV=1
PDP1_YEAST42.145%4013.73e-99[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PTC5 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9994
Predicted cleavage: 154

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 639

Detailed signature matches

    1. SM00332 (PP2C_4)
    2. PF00481 (PP2C)
    3. SSF81606 (PP2C-like)
    4. PS51746 (PPM_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00143 (PP2Cc)
  2. mobidb-lite (disord...)

Residue annotation

  1. Active site cd00143

Protein sequence

>MIA_04186_1
MLKVRAASRGSANSTIRRRLQSSSSASLPAVSAVNSGAALRRSPSPTRSPPRRQLSTSSSAPPSASVTGFRPLARWSSVA
VVATSILLAGSYLTLAPRHAAISLESSSPFSTSAPFGLPRSSSQQSNKQPITMMTPLQVSARLRELEESYFVERGKGVVR
YDVSQLPSNSPIEDDRSEKIVQVPLLTAAGDKTDTEAKAISSDWMFWGVYDGHSGWTTSAKLRDALIAYVLSELDKTYVK
STPDSIYRLVPSPTAIDEAIQNGFVRLDNDIVHKSIEKLMAHPDKAGAAEYIAPALSGSCGLLAFYDTFSHNLRVAVTGD
SRAVLGSVNERGEWTARALSVDQTGSNMEEAARIRKEHPGEESTVIRRGRVLGMLEPTRAFGDARYKWTRDIQEKMVRYF
FGRRVPADFHSPPYVTAKPVVSTTHITPKAGDFLVLGTDGLYEMLTNEEIVGLVVQWLHKKKPDYFEQVQATIKERAASK
TLWGRVFGTGSSSSSKSDSSSNSAAEATSPAPATKAPASPGTIIKADHSELAVRVRDVSPHPESQKQVFRRQPGTTPRFT
VEDENIATHLVRNALGGADIQQVSMLVSIPAPISRSYRDDLTVTVVLFGDAGEANDSGSVRVNEDGTRKNLKTHIKSKL

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.