Protein

MIA_04158_1

Length
338 amino acids

Browser: contig05:938058-939075-

Protein function

EGGNOG:0PHZADIM1dimethyladenosine transferase
SGD closest match:S000006187DIM1Dimethyladenosine transferase
CGD closest match:CAL0000196194DIM1rRNA adenine N(6)-methyltransferase

Protein alignments

%idAln lengthE-value
MCA_00100_183.660%3060.0MCA_00100_1
A0A1E3PN98_9ASCO76.699%3091.06e-178rRNA adenine N(6)-methyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50242 PE=3 SV=1
A0A0J9XD13_GEOCN75.329%3048.53e-174rRNA adenine N(6)-methyltransferase OS=Geotrichum candidum GN=BN980_GECA11s00516g PE=3 SV=1
A0A167FDW5_9ASCO73.846%3256.54e-173rRNA adenine N(6)-methyltransferase OS=Sugiyamaella lignohabitans GN=DIM1 PE=3 SV=1
Q5AKW7_CANAL75.329%3043.89e-168rRNA adenine N(6)-methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DIM1 PE=3 SV=1
UniRef50_J7RSG272.468%3161.39e-164rRNA adenine N(6)-methyltransferase n=14 Tax=Fungi TaxID=4751 RepID=J7RSG2_KAZNA
DIM1_YEAST68.047%3383.05e-167Dimethyladenosine transferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DIM1 PE=3 SV=1
DIM1_YARLI70.550%3094.60e-164Dimethyladenosine transferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DIM1 PE=3 SV=1
A0A060T0H6_BLAAD67.492%3231.64e-159rRNA adenine N(6)-methyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C13376g PE=3 SV=1
A0A1E4TFQ0_9ASCO68.371%3131.51e-158rRNA adenine N(6)-methyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_148012 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8291
Predicted cleavage: 16

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 338

Detailed signature matches

  1. Family IPR001737
    Ribosomal RNA adenine methyltransferase KsgA/Erm
    1. PS51689 (SAM_RNA_A_...)
    2. PF00398 (RrnaAD)
  2. Family IPR011530
    Ribosomal RNA adenine dimethylase
    1. TIGR00755
  3. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
  4. Domain IPR020598
    Ribosomal RNA adenine methylase transferase, N-terminal
    1. SM00650 (rADcneu6)
  5. SITE IPR020596
    Ribosomal RNA adenine methylase transferase, conserved site
    1. PS01131 (RRNA_A_DIMETH)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd02440 (AdoMet_MTases)

Residue annotation

  1. S-adenosylmethioni...

Protein sequence

>MIA_04158_1
MGKAVKVKSNSAARQTTTAAATGIKTDMGTGAGAKKTSVFTMNTGIGQHILKNPLVAQGIVDKADIKPSDTVLEVGPGTG
NLTVRILEKARKLYAVEMDPRMASELTKRVQGHPEWQKKLEIMLGDVIKTELPQHDICISNTPYQISSPLVFKLLTMPRP
PRVAILMFQREFALRLLARPGDNLYCRLSVNTQMWARVTHIMKVGRNNFRPPPNVESSVVRIEIKNPRPDISFEEWDGLL
RICFVRKNRTISAGFKSPSVIEILAKNYKTIMSMKQSDNDAMMEDTPTDDKAIENLIKEKIETVLTTTKLGEQRAGKCTE
TDFLKLLHAFHQVDIHFA

GO term prediction

Biological Process

GO:0000154 rRNA modification
GO:0006364 rRNA processing

Molecular Function

GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity
GO:0008649 rRNA methyltransferase activity

Cellular Component

None predicted.