Protein

MCA_00100_1

Length
330 amino acids

Gene name: DIM1

Description: Dimethyladenosine transferase

Browser: contigA:274087-275080-

RNA-seq: read pairs 699, FPKM 26.1, percentile rank 48.8% (100% = highest expression)

Protein function

Annotation:DIM1Dimethyladenosine transferase
KEGG:K14191DIM1 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase [EC:2.1.1.183]
EGGNOG:0PHZADIM1dimethyladenosine transferase
SGD closest match:S000006187DIM1Dimethyladenosine transferase
CGD closest match:CAL0000196194DIM1rRNA adenine N(6)-methyltransferase

Protein alignments

%idAln lengthE-value
MIA_04158_183.66%3060.0MIA_04158_1
A0A1E3PN98_9ASCO70.09%3313e-169rRNA adenine N(6)-methyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50242 PE=3 SV=1
A0A0J9XD13_GEOCN71.85%3021e-167rRNA adenine N(6)-methyltransferase OS=Geotrichum candidum GN=BN980_GECA11s00516g PE=3 SV=1
A0A167FDW5_9ASCO69.82%3282e-166rRNA adenine N(6)-methyltransferase OS=Sugiyamaella lignohabitans GN=DIM1 PE=3 SV=1
Q5AKW7_CANAL68.86%3342e-166rRNA adenine N(6)-methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DIM1 PE=3 SV=1
UniRef50_P7869767.88%3302e-159Dimethyladenosine transferase n=97 Tax=cellular organisms TaxID=131567 RepID=DIM1_KLULA
DIM1_YARLI65.96%3323e-160Dimethyladenosine transferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DIM1 PE=3 SV=1
DIM1_YEAST64.46%3322e-156Dimethyladenosine transferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DIM1 PE=3 SV=1
A0A1E4TFQ0_9ASCO64.92%3253e-152rRNA adenine N(6)-methyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_148012 PE=3 SV=1
A0A060T0H6_BLAAD61.14%3503e-150rRNA adenine N(6)-methyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C13376g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7374
Predicted cleavage: 15

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 330

Detailed signature matches

  1. Family IPR001737
    Ribosomal RNA adenine methyltransferase KsgA/Erm
    1. PS51689 (SAM_RNA_A_...)
    2. PF00398 (RrnaAD)
  2. Family IPR011530
    Ribosomal RNA adenine dimethylase
    1. TIGR00755
  3. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
  4. Domain IPR020598
    Ribosomal RNA adenine methylase transferase, N-terminal
    1. SM00650 (rADcneu6)
  5. SITE IPR020596
    Ribosomal RNA adenine methylase transferase, conserved site
    1. PS01131 (RRNA_A_DIMETH)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd02440 (AdoMet_MTases)
  3. mobidb-lite (disord...)

Residue annotation

  1. S-adenosylmethioni...

Protein sequence

>MCA_00100_1
MGKAPKQRSSASRQPGGGIPVLENTNTAKKTSVFTMNTGIGQHILKNPLVAQGIVDKAEIKPSDTVLEVGPGTGNLTVRI
LEKARKLYAIEMDPRMASELTKRVQGHPDWEKKLQITLSDVIKLDLPYHDVCISNTPYQISSPLVFKILTMKNPPRVAIL
MFQREFALRLLARPGDTLYCRLSVNAQMWSRITHIMKVGRNNFRPPPNVESSVVRIEIKNPRPDISFEEWDGMLRICFVR
KNRTIAAGFKTPSVLEILTKNYKTLMSVQNQDNAEAVMELDDKSLTLEVKDKIEKVLTTTGLAEKRAGKCSEKDFLTLLH
AFHQVGIHFA

GO term prediction

Biological Process

GO:0000154 rRNA modification
GO:0006364 rRNA processing

Molecular Function

GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity
GO:0008649 rRNA methyltransferase activity

Cellular Component

None predicted.