MIA_04149_1

Protein

Length

463 amino acids

Protein function

EGGNOG:	0PGQF	FG08982.1	complex, subunit
SGD closest match:	S000006180	APM1	AP-1 complex subunit mu-1-I
CGD closest match:	CAL0000186413	APM1	Apm1p

Protein alignments

	%id	Aln length	E-value
MCA_00090_1	82.189%	466	0.0	MCA_00090_1
A0A060T0E8_BLAAD	72.017%	461	0.0	ARAD1C12518p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C12518g PE=3 SV=1
A0A167BXE1_9ASCO	70.933%	461	0.0	Apm1p OS=Sugiyamaella lignohabitans GN=APM1 PE=3 SV=1
A0A0J9X2R5_GEOCN	71.581%	468	0.0	Similar to Saccharomyces cerevisiae YPL259C APM1 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1) OS=Geotrichum candidum GN=BN980_GECA01s09393g PE=3 SV=1
Q6CEZ3_YARLI	68.365%	471	0.0	YALI0B11682p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B11682g PE=3 SV=1
A0A1E3PIE8_9ASCO	68.026%	466	0.0	Clathrin adaptor, mu subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46920 PE=3 SV=1
UniRef50_A0A0F0IQC0	66.740%	454	0.0	Adaptor complexes medium subunit family protein n=8 Tax=leotiomyceta TaxID=716546 RepID=A0A0F0IQC0_ASPPU
A0A1E4TG63_9ASCO	62.554%	462	0.0	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_110094 PE=3 SV=1
AP1M1_YEAST	53.196%	485	0.0	AP-1 complex subunit mu-1-I OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APM1 PE=1 SV=2
Q5AJY4_CANAL	51.173%	469	1.59e-175	Apm1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=APM1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2031

Protein family membership

Clathrin adaptor, mu subunit (IPR001392)

Domains and repeats

Domain
1 - 140
Longin-like domain (IPR011012)
AP complex, mu/sigma subunit (IPR022775)
156 - 460
Mu homology domain (IPR028565)

1 50 100 150 200 250 300 350 400 463

Detailed signature matches

IPR001392

Clathrin adaptor, mu subunit
1. PIRSF005992 (AP_com...)
  
  1 - 460
  
  PIRSF
  PIRSF005992 (AP_complex_mu)
2. PR00314 (CLATHRINADPT)
  
  100 - 127
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  158 - 186
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  248 - 275
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  12 - 32
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  317 - 332
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  357 - 368
  
  PRINTS
  PR00314 (CLATHRINADPT)
IPR011012

Longin-like domain
1. SSF64356 (SNARE-like)
  
  1 - 140
  
  SUPERFAMILY
  SSF64356 (SNARE-like)
IPR022775

AP complex, mu/sigma subunit
1. PF01217 (Clat_adapt...)
  
  3 - 132
  
  Pfam
  PF01217 (Clat_adaptor_s)
IPR028565

Mu homology domain
1. SSF49447 (Second do...)
  
  156 - 459
  
  SUPERFAMILY
  SSF49447 (Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor)
2. PF00928 (Adap_comp_sub)
  
  156 - 460
  
  Pfam
  PF00928 (Adap_comp_sub)
3. PS51072 (MHD)
  
  167 - 459
  
  PROSITE profiles
  PS51072 (MHD)
IPR018240

Clathrin adaptor, mu subunit, conserved site
1. PS00990 (CLAT_ADAPT...)
  
  156 - 176
  
  PROSITE patterns
  PS00990 (CLAT_ADAPTOR_M_1)
2. PS00991 (CLAT_ADAPT...)
  
  268 - 282
  
  PROSITE patterns
  PS00991 (CLAT_ADAPTOR_M_2)

no IPR

Unintegrated signatures

G3DSA:2.60.40...

149 - 326

GENE3D
G3DSA:2.60.40.1170 (G3DSA:2.60.40.1170)

407 - 454

GENE3D
G3DSA:2.60.40.1170 (G3DSA:2.60.40.1170)
G3DSA:3.30.45...

1 - 142

GENE3D
G3DSA:3.30.450.60 (G3DSA:3.30.450.60)
cd09250 (AP-1_Mu1_C...)

153 - 457

CDD
cd09250 (AP-1_Mu1_Cterm)
mobidb-lite (disord...)

380 - 406

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

heterotetramer int...

165Y

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

185T

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

187K

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

189L

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

190R

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

200K

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

210R

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

249E

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

252K

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

276E

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

283R

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

285N

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

299R

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

311R

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

313R

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

319R

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

324D

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

343S

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

348K

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

351P

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

352E

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

361K

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

367K

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

368E

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

370E

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

415K

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

416F

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

417T

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

420F

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

429R

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

430Y

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

431L

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

432K

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

442S

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

443Y

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

444P

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

445W

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

446V

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

451K

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

453G

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)

454D

heterotetramer interface
165Y, 185T, 187K, 189L, 190R, 200K, 210R, 249E, 252K, 276E, 283R, 285N, 299R, 311R, 313R, 319R, 324D, 343S, 348K, 351P, 352E, 361K, 367K, 368E, 370E, 415K, 416F, 417T, 420F, 429R, 430Y, 431L, 432K, 442S, 443Y, 444P, 445W, 446V, 451K, 453G, 454D
CDD
cd09250 (AP-1_Mu1_Cterm)
signal peptide bin...

171F

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

172L

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

173D

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

200K

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

323N

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

417T

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

419P

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

444P

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

445W

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

446V

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

447R

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

449V

signal peptide binding site
171F, 172L, 173D, 200K, 323N, 417T, 419P, 444P, 445W, 446V, 447R, 449V
CDD
cd09250 (AP-1_Mu1_Cterm)

Protein sequence

>MIA_04149_1
MASAIFFLDMKGKPLLSRNYRGDIPMSAVERFPLLLMEAEEESSVVPPCFSKEGVHYLYITHNDLYVLALSKRNANAAEI
LLFLHRIVKVLTEYFKRLTEESIRDNFVVIYELLDEMMDFGHPQTTETQILQEYITQKSHQLNVQVRPPVAVTNAVSWRS
EGLKYNKNEAFLDVVESVNMMVSPTGKVLRSEILGSIQMKCFLSGMPELRLGLNDRVIFDRQSNTTGQIINPNGSGGRSA
GGKGSIELEDVKFHQCVRLSRFESDRTISFIPPDGEFELMSYRLNTTVKPLIWVDCQIRNFSNTRIEIKARARAQFKSRS
HANDIDITIPVPEDADSPRLKVSQGTAKWKPELAAIVWHIKKLVGGKEIELSAQLNLPSVRENDDGGSSLAGGRDGHPST
YLEGGSSAQNPISVKFTIPFYTTSGIQVRYLKIIEPKLQYPSYPWVRYVTKSGDDYTIRIARY

GO term prediction

Biological Process

GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport

Molecular Function

None predicted.

Cellular Component

GO:0030131 clathrin adaptor complex

Filter view on

Entry type

Status

Per-residue features