Protein

MCA_00090_1

Length
464 amino acids


Gene name: APM1

Description: Mu1-like medium subunit of the AP-1 complex, clathrin adaptor protein

Browser: contigA:238636-240031+

RNA-seq: read pairs 6154, FPKM 163.5, percentile rank 85.8% (100% = highest expression)

Protein function

Annotation:APM1Mu1-like medium subunit of the AP-1 complex, clathrin adaptor protein
KEGG:K12393AP1M AP-1 complex subunit mu
EGGNOG:0PGQFFG08982.1complex, subunit
SGD closest match:S000006180APM1AP-1 complex subunit mu-1-I
CGD closest match:CAL0000186413APM1Apm1p

Protein alignments

%idAln lengthE-value
MIA_04149_182.62%4660.0MIA_04149_1
A0A167BXE1_9ASCO73.16%4620.0Apm1p OS=Sugiyamaella lignohabitans GN=APM1 PE=3 SV=1
A0A060T0E8_BLAAD71.86%4620.0ARAD1C12518p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C12518g PE=3 SV=1
A0A0J9X2R5_GEOCN72.61%4710.0Similar to Saccharomyces cerevisiae YPL259C APM1 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1) OS=Geotrichum candidum GN=BN980_GECA01s09393g PE=3 SV=1
Q6CEZ3_YARLI65.89%4720.0YALI0B11682p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B11682g PE=3 SV=1
A0A1E3PIE8_9ASCO66.95%4660.0Clathrin adaptor, mu subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46920 PE=3 SV=1
UniRef50_A0A0F0IQC067.25%4550.0Adaptor complexes medium subunit family protein n=8 Tax=leotiomyceta TaxID=716546 RepID=A0A0F0IQC0_ASPPU
A0A1E4TG63_9ASCO64.36%4630.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_110094 PE=3 SV=1
AP1M1_YEAST53.07%4882e-180AP-1 complex subunit mu-1-I OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APM1 PE=1 SV=2
Q5AJY4_CANAL56.38%4704e-177Apm1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=APM1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3393

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 464

Detailed signature matches

    1. PIRSF005992 (AP_com...)
    2. PR00314 (CLATHRINADPT)
    1. SSF64356 (SNARE-like)
    1. PF01217 (Clat_adapt...)
    1. SSF49447 (Second do...)
    2. PF00928 (Adap_comp_sub)
    3. PS51072 (MHD)
    1. PS00991 (CLAT_ADAPT...)
    2. PS00990 (CLAT_ADAPT...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd09250 (AP-1_Mu1_C...)

Residue annotation

  1. heterotetramer int...
  2. signal peptide bin...

Protein sequence

>MCA_00090_1
MASAIFFLDMKGKPLLSRNYRGDIPMSAIEKFPLLLLEAEEETSVVPPCISKDGINYLYITHNDLFVLALTRRNSNAAEI
LLFLHRIVKVLTEYFKRLTEESIRDNFVIIYELLDEMMDFGYPQTTETQILQEYITQESHALDVQVKPPVAVTNAVSWRS
EGIYYKKNEAFLDVIESVNMMVSPTGKVLSSEILGSIQMKCFLSGMPELRLGLNDRVIFDRQSNTTGQIMPTTRGGAGPG
KGPIELEDIKFHQCVRLSRFESDRTISFIPPDGEFELMSYRLNTSVKPLIWVDCRFRNFSNTRIEIQARARAQFKSRSHA
NDIDIVIPVPDDADSPRFKTSSGSVKWKPEISAVVWHMKKLVGGKEAVMTAELNLPSVRGDDDAAVTSGEVGLVGAVSNS
STGANFGSYKKPISVKFTIPFFTTSGIQVRYLKIIEPKLQYPSYPWVRYVTKSGNDYTIRIAKY

GO term prediction

Biological Process

GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport

Molecular Function

None predicted.

Cellular Component

GO:0030131 clathrin adaptor complex