Protein
MIA_04129_1
Length
573 amino acids
Browser: contig05:845687-847409+
Protein function
EGGNOG: | 0PG3T | PUT2 | Delta-1-pyrroline-5-carboxylate dehydrogenase |
---|---|---|---|
SGD closest match: | S000001079 | PUT2 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial |
CGD closest match: | CAL0000194832 | PUT2 | 1-pyrroline-5-carboxylate dehydrogenase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_00072_1 | 79.41% | 573 | 0.0 | MCA_00072_1 |
A0A1E3PE92_9ASCO | 69.63% | 563 | 0.0 | Delta-1-pyrroline-5-carboxylate dehydrogenase 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48039 PE=3 SV=1 |
A0A0J9XD55_GEOCN | 69.40% | 549 | 0.0 | Similar to Saccharomyces cerevisiae YHR037W PUT2 Delta-1-pyrroline-5-carboxylate dehydrogenase OS=Geotrichum candidum GN=BN980_GECA08s04443g PE=3 SV=1 |
A0A167E4T6_9ASCO | 68.29% | 574 | 0.0 | 1-pyrroline-5-carboxylate dehydrogenase OS=Sugiyamaella lignohabitans GN=PUT2 PE=3 SV=1 |
A0A060T6A1_BLAAD | 64.22% | 573 | 0.0 | ARAD1B10098p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10098g PE=3 SV=1 |
Q6CF74_YARLI | 61.63% | 576 | 0.0 | YALI0B09647p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B09647g PE=4 SV=1 |
Q5AK46_CANAL | 60.85% | 544 | 0.0 | 1-pyrroline-5-carboxylate dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PUT2 PE=3 SV=1 |
UniRef50_G0SEX2 | 60.61% | 556 | 0.0 | Delta-1-pyrroline-5-carboxylate dehydrogenase-like protein n=1 Tax=Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) TaxID=759272 RepID=G0SEX2_CHATD |
A0A1E4TB31_9ASCO | 58.36% | 562 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32308 PE=3 SV=1 |
PUT2_YEAST | 56.56% | 564 | 0.0 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PUT2 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.8203
Predicted cleavage: 13
Protein family membership
- Delta-1-pyrroline-5-carboxylate dehydrogenase (IPR005931)
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
573
Detailed signature matches
no IPR
Unintegrated signatures
-
-
NON_CYTOPLASM... (N...)
-
SIGNAL_PEPTIDE (Sig...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
Residue annotation
-
Glutamate binding ...
-
NAD binding site c...
-
catalytic residues...
Protein sequence
>MIA_04129_1 MIRTLSSKKTLSVGTAAAAKSYSTAVPQWATFKVPQIKNEPVRAFPPGSKDRAGVIEALKKYKGTADIPAVIGGKEIFND TTFKQRSPFNHEHVVANVSSTTPAQVREAIEASNAAKRDWENAPWADRAAVFLKAADLITGKYRYDMLATTMIGQGKNAF QAEIDATCELSDFLRFNTRYAEELYAQQPTETTPGSWNRAEYRPLEGFTYAVTPFNFTAISGNLVAAPALMGNTVVWKPS DSAVLSNYLLYNIFKEAGLPDGVINFIPGDAQSVTEEVLSSPDFAALHFTGSTQVFLSLYQKIASNLASYKSYPRIVGET GGKNFHVIHNSADIENAVKSTVRGSFEFQGQKCSATSRAYIPRSIWPQFKDLLIKETEKIHAHQGDATNATGFHYFAGPV IHEPSFNKLVNVFKKAESDPALKLLIGGTADKSVGYYVKPTIYQATDPNHPYLSTEFFGPVLTVYVYEDAEFEQTLSLVD KATKYGLTGSIFARDRNAISQATYALRHSAGNFYINDKSTGAVVGQQWFGGARMSGTNDKAGSGNILTRFVSVRNIKESF VGLDDIFYPSNQQ
GO term prediction
Biological Process
GO:0008152 metabolic process
GO:0010133 proline catabolic process to glutamate
GO:0055114 oxidation-reduction process
Molecular Function
GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity
GO:0016491 oxidoreductase activity
Cellular Component
None predicted.