Protein

MIA_04122_1

Length
493 amino acids

Browser: contig05:823100-824582-

Protein function

EGGNOG:0PFQDMPK1Mitogen-activated protein kinase
SGD closest match:S000001072SLT2Mitogen-activated protein kinase SLT2/MPK1
CGD closest match:CAL0000183747MKC1Mitogen-activated protein kinase MKC1

Protein alignments

%idAln lengthE-value
MCA_00064_187.64%3640.0MCA_00064_1
A0A0J9XE26_GEOCN84.66%3650.0Mitogen-activated protein kinase OS=Geotrichum candidum GN=BN980_GECA12s01484g PE=3 SV=1
A0A161HHS8_9ASCO84.66%3650.0Mitogen-activated protein kinase OS=Sugiyamaella lignohabitans GN=SLT2 PE=3 SV=1
A0A060T360_BLAAD85.64%3620.0Mitogen-activated protein kinase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38236g PE=3 SV=1
Q6CFX3_YARLI84.76%3610.0Mitogen-activated protein kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B02816g PE=3 SV=1
A0A1E3PHI8_9ASCO79.78%3610.0PMAP kinase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_10195 PE=3 SV=1
UniRef50_D3J12775.62%3610.0Mitogen-activated protein kinase n=17 Tax=Fungi TaxID=4751 RepID=D3J127_ALTAL
SLT2_YEAST72.18%3630.0Mitogen-activated protein kinase SLT2/MPK1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLT2 PE=1 SV=2
A0A1E4TAJ3_9ASCO73.97%3650.0Mitogen-activated protein kinase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29043 PE=3 SV=1
MKC1_CANAL69.58%3780.0Mitogen-activated protein kinase MKC1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MKC1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0748

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 493

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR003527
    Mitogen-activated protein (MAP) kinase, conserved site
    1. PS01351 (MAPK)
  5. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. PIRSF000615 (TyrPK_...)
  5. cd07857 (STKc_MPK1)
  6. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd07857
  3. polypeptide substr...
  4. KIM docking site c...
  5. activation loop (A...

Protein sequence

>MIA_04122_1
MDLSQPERHTYRVSNQDFTIDRRFHITKELGHGAYGIVCAATYTGTPDGAPGPGVAIKKVTNIFSKKILCKRALRELKLL
NHFRGHKNITCLYDMDIVTLPNFNEVYLYEELLECDMHQIIRSQQPLTDAHYQSFIYQILAGLKYIHSANVLHRDLKPGN
LLVNSDCELKICDFGLARGFSTDPTRNAGFLTEYVATRWYRAPEIMLSFQSYTKAIDVWSVGCILAELLGGKPIFKGRDY
VDQLCQILNYLGTPPEETLARIGSQRAQEYVRKLPYTPKIPFSQLYPQANPEALDLLERMLAFDPTDRITVQEALEHPYL
RIWHDPADEPECPKEFDFSFEEVDDMEAMRQMILDEVVNFRAMVRRPPEQQQQQLHIDVQQASQQQQQPTQEMFAGQFTD
NSLAIQQQLQQQQQQLQQAQIQQYQQQQLQQQNAAAAAAAAAVAAANNKRDSIGIPSDQFRYTDLPPRPQENINDGEVID
ALERDLEFGLDGR

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004707 MAP kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.