Protein

MCA_00064_1

Length
476 amino acids

Gene name: SLT2A

Description: mitogen-activated protein kinase

Browser: contigA:159093-160524-

RNA-seq: read pairs 2595, FPKM 67.2, percentile rank 71.7% (100% = highest expression)

Protein function

Annotation:SLT2Amitogen-activated protein kinase
EGGNOG:0PFQDMPK1Mitogen-activated protein kinase
SGD closest match:S000001072SLT2Mitogen-activated protein kinase SLT2/MPK1
CGD closest match:CAL0000183747MKC1Mitogen-activated protein kinase MKC1

Protein alignments

%idAln lengthE-value
MIA_04122_187.64%3640.0MIA_04122_1
A0A161HHS8_9ASCO85.67%3630.0Mitogen-activated protein kinase OS=Sugiyamaella lignohabitans GN=SLT2 PE=3 SV=1
A0A060T360_BLAAD84.34%3640.0Mitogen-activated protein kinase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38236g PE=3 SV=1
A0A0J9XE26_GEOCN85.04%3610.0Mitogen-activated protein kinase OS=Geotrichum candidum GN=BN980_GECA12s01484g PE=3 SV=1
Q6CFX3_YARLI82.19%3650.0Mitogen-activated protein kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B02816g PE=3 SV=1
A0A1E3PHI8_9ASCO81.22%3620.0PMAP kinase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_10195 PE=3 SV=1
UniRef50_A0A0F8DI0976.40%3560.0Mitogen-activated protein kinase n=16 Tax=Fungi TaxID=4751 RepID=A0A0F8DI09_CERFI
A0A1E4TAJ3_9ASCO75.14%3540.0Mitogen-activated protein kinase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29043 PE=3 SV=1
SLT2_YEAST71.90%3630.0Mitogen-activated protein kinase SLT2/MPK1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLT2 PE=1 SV=2
MKC1_CANAL69.66%3790.0Mitogen-activated protein kinase MKC1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MKC1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0781

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 476

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR003527
    Mitogen-activated protein (MAP) kinase, conserved site
    1. PS01351 (MAPK)
  5. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. PIRSF000615 (TyrPK_...)
  5. cd07857 (STKc_MPK1)
  6. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd07857
  3. polypeptide substr...
  4. KIM docking site c...
  5. activation loop (A...

Protein sequence

>MCA_00064_1
MAQSERHTYKVSNQDFTIDRRFQITKELGHGAYGIVCAANYVDSIDAPGVAIKKVTNIFSKKILCKRALRELKLLKHFRG
HKNITCLYDMDIVNVNNFNEVYLYEELLECDMHQIIRSQQPLTDAHYQSFIYQILVGLKYIHSANVLHRDLKPGNLLVNS
DCELKICDFGLARGYSSDPDRNAGFLTEYVATRWYRAPEIMLSFQSYTKAIDVWSVGCILAELLGGKPIFKGRDYVDQLC
QILHYLGTPPEETLARIGSARAQAYVRSLPYNPKIPFETLFPKANPEALDLLEKMLAFDPADRITVQDALEHPYLKIWHD
PADEPDCPQTFDFSFEEVDDLDTMRQMILDEVLNFRQAVRQGLNEQQQQQPQQQESEKNNVVESQSQQDIQRQVDAQQAE
AMAQAQAQALAQAQAQAQAQAQAQAEAEAQAQAIAQAQAQAQAQAQAQAMAQAQAQMQAQAYQAQAQAQAMAQAQA

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004707 MAP kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.